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systeemziekten

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systeemziekten verschillen in kliniek tussen GPA en MPA MPA: minder NKO klachten, net meer longbloedingen en neuopathie klachten nooit granuloomvorming bij MPA MPA heeft minder neiging om te hervallen dan GPA longfibrose is mogelijk bij MPA maar NOOIT bij GPA items die D/ MPA minder waarschijnlijk maken c-ANCA tegen PR3 eosinofielen NKO aantasting longbloeding + nieraantasting bij MPA: wat gaan we extra bepalen voor onze DD/? antiGBM antistoffen - uitsluiten van syndroom van Goodpasture welke medicatie lokt een ANCA vasculitis mogelijks uit? (MPO ANCA vooral) PTU hydralazine minocyline longfibrose: welke systeemaandoening kan onderliggend zijn? MPA 3 fasen van EGPA 1. prodromale fase (astma, allergische rinitis) 2. eosinofiele fase (bloed, longen, GI stelsel) 3. vascultits fase (koorts, gewichtsverlies, vermoeidheid, CMP, pericarditis, neuropathie)


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