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Exam (elaborations)

reumatologie systeemziekten

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reumatologie systeemziekten Welke drie constitutionele symptomen komen vaak voor bij SLE? Koorts, vermagering en nachtzweten (ook vermoeidheid) door adenopathieën (abnormaal dikke klieren) en splenomegalie (vergrootte milt). De diagnose van SLE wordt gesteld op basis van patroonherkenning bij een typische patiënt... namelijk een jonge vrouw met constitutionele, articulaire en cutane klachten (met specifieke antistoffen en andere biochemische afwijkingen) Wat is de belangrijkste niet-medicamenteuze behandeling of preventieve maatregel bij SLE? Strikte UV-protectie + gezond leef- en bewegingspatroon Wat zijn de drie kenmerken van systeemsclerose? Aanwezigheid van auto-antistoffen, vasculaire afwijkingen en fibrose. Wat is de incidentie van systeemsclerose per jaar? 10 per 1.000.000 per jaar. Wat is de typische leeftijd voor het ontstaan van systeemsclerose? 50-55 jaar. Wat is de mortaliteit op 10 jaar voor de diffuse vorm van systeemsclerose? 30%. Wat is de vasculaire kliniek bij systeemsclerose? - raynaudfenomeen - trofische letsels thv vingertoppen - teleangiëctasieën


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