NURS 334 UPDATED FINAL EXAM ALL
QUESTIONS AND ANSWERS SURE A+
✔✔Drug Trial Phase 0 - ✔✔drug testing occurs in animals and small groups of humans
✔✔Drug Trial Phase 1 - ✔✔few doses are given to a certain number of healthy
volunteers to determine safe dosages, routes of administration, absorption, metabolism,
excretion, and toxicity
✔✔Drug Trial Phase 2 - ✔✔few doses are given to a certain number of subjects with the
disease or symptom for which the drug is being studied, and responses are compared
with those of healthy subjects
✔✔Drug Trial Phase 3 - ✔✔drug is given to different populations and different dosages
and by using the drug in combination with other drugs. In double-blind, placebo-
controlled designs, half of the subjects receive the new drug and half receive a placebo,
with neither subjects nor researchers knowing who receives which formulation
✔✔placebo - ✔✔an inactive substance similar in appearance to the actual drug
✔✔Drug Trial Phase 4 - ✔✔the FDA allows the drug to be marketed and requires
manufacturers to continue postmarketing monitoring and electronic report submission of
the drug's safety and effectiveness
, ✔✔BLACK BOX WARNINGS (BBWs) - ✔✔These are about drugs that can cause
serious adverse effects and the warning appears on the label, package insert, and any
marketing literature
✔✔QSEN competencies - ✔✔Patient-Centered Care
Teamwork and Collaboration
Evidence-Based Practice
Quality Improvement
Safety
Informatics
✔✔cells common characteristics - ✔✔1.exchange materials with their immediate
environment
2. Obtain energy from nutrients
3.Synthesize hormones, neurotransmitters, enzymes, 4.structural proteins, and other
complex molecules
5.Reproduce
6. Communicate with one another via various biologic chemicals, such as
neurotransmitters and hormones
✔✔Protoplasm - ✔✔constitutes the internal environment of body cells, is composed of
water, electrolytes (potassium, magnesium, phosphate, sulfate, bicarbonate), proteins,
lipids, and carbohydrates
✔✔nucleus - ✔✔regulates the types and amounts of proteins, enzymes, and other
substances to be produced
✔✔cytoplasm - ✔✔surrounds the nucleus
✔✔endoplasmic reticulum (ER) - ✔✔contains ribosomes, which synthesize proteins,
including enzymes that synthesize glycogen, triglycerides, and steroids and those that
metabolize drugs and other chemicals
✔✔cell membrane - ✔✔A cell structure that controls which substances can enter or
leave the cell.
✔✔Golgi complex - ✔✔a cell organelle that helps make and package materials to be
transported out of the cell
✔✔carbohydrates - ✔✔in the cell membrane occur mainly in combination with proteins
(glycoproteins) or lipids (glycolipids).
✔✔Pharmacokinetics - ✔✔involves drug movement through the body (i.e., "what the
body does to the drug") to reach sites of action, metabolism, and excretion
QUESTIONS AND ANSWERS SURE A+
✔✔Drug Trial Phase 0 - ✔✔drug testing occurs in animals and small groups of humans
✔✔Drug Trial Phase 1 - ✔✔few doses are given to a certain number of healthy
volunteers to determine safe dosages, routes of administration, absorption, metabolism,
excretion, and toxicity
✔✔Drug Trial Phase 2 - ✔✔few doses are given to a certain number of subjects with the
disease or symptom for which the drug is being studied, and responses are compared
with those of healthy subjects
✔✔Drug Trial Phase 3 - ✔✔drug is given to different populations and different dosages
and by using the drug in combination with other drugs. In double-blind, placebo-
controlled designs, half of the subjects receive the new drug and half receive a placebo,
with neither subjects nor researchers knowing who receives which formulation
✔✔placebo - ✔✔an inactive substance similar in appearance to the actual drug
✔✔Drug Trial Phase 4 - ✔✔the FDA allows the drug to be marketed and requires
manufacturers to continue postmarketing monitoring and electronic report submission of
the drug's safety and effectiveness
, ✔✔BLACK BOX WARNINGS (BBWs) - ✔✔These are about drugs that can cause
serious adverse effects and the warning appears on the label, package insert, and any
marketing literature
✔✔QSEN competencies - ✔✔Patient-Centered Care
Teamwork and Collaboration
Evidence-Based Practice
Quality Improvement
Safety
Informatics
✔✔cells common characteristics - ✔✔1.exchange materials with their immediate
environment
2. Obtain energy from nutrients
3.Synthesize hormones, neurotransmitters, enzymes, 4.structural proteins, and other
complex molecules
5.Reproduce
6. Communicate with one another via various biologic chemicals, such as
neurotransmitters and hormones
✔✔Protoplasm - ✔✔constitutes the internal environment of body cells, is composed of
water, electrolytes (potassium, magnesium, phosphate, sulfate, bicarbonate), proteins,
lipids, and carbohydrates
✔✔nucleus - ✔✔regulates the types and amounts of proteins, enzymes, and other
substances to be produced
✔✔cytoplasm - ✔✔surrounds the nucleus
✔✔endoplasmic reticulum (ER) - ✔✔contains ribosomes, which synthesize proteins,
including enzymes that synthesize glycogen, triglycerides, and steroids and those that
metabolize drugs and other chemicals
✔✔cell membrane - ✔✔A cell structure that controls which substances can enter or
leave the cell.
✔✔Golgi complex - ✔✔a cell organelle that helps make and package materials to be
transported out of the cell
✔✔carbohydrates - ✔✔in the cell membrane occur mainly in combination with proteins
(glycoproteins) or lipids (glycolipids).
✔✔Pharmacokinetics - ✔✔involves drug movement through the body (i.e., "what the
body does to the drug") to reach sites of action, metabolism, and excretion
