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1. The process of DNA replication requires that each of (c) template
the parental DNA strands be used as a ____________ to
produce a duplicate of the opposing strand.
(a) catalyst
(b) competitor
(c) template
(d) copy
2. DNA replication is considered semiconservative be- (c) each daughter DNA
cause __________________________________. molecule consists of one
(a) after many rounds of DNA replication, the original strand from the parent
DNA double helix is still intact. DNA molecule and one
(b) each daughter DNA molecule consists of two new new strand
strands copied form the parent
(c) each daughter DNA molecule consists of one strand
from the parent DNA molecule and one new strand.
3. The classic experiment conducted by Meselson and semiconservative
Stahl demonstrated that DNA replication is accom-
plished by employing a ______________ mechanism.
4. Initiator proteins bind to replication origins and dis- (b) the reaction can occur
rupt hydrogen bonds between the two DNA strands at room temperature
being copied. Which of the factors below does not
contribute to the relative ease of strand separation by
initiator proteins?
(a) replication origins are rich in A-T base pairs
(b) the reaction can occur at room temperature
(c) they only separate a few base pairs at a time
(d) once opened, other portions of the DNA replication
machinery bind to the origin
, Intro to Molecular Cell Biology Test Bank Chapter 6
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5. If the genome of the bacterium E. coli requires about (d) Fruit fly DNA contains
20 minutes to replicate itself, how can the genome of more origins of replication
a fruit fly be replicated in only 3 minutes? than E coli DNA
(a) The fruit fly genome is smaller than E coli
(b) Eukaryotic DNA polymerase synthesizes DNA at a
much faster rate than prokaryotic
(c) The nuclear membrane keeps the fruit fly DNA con-
centrated in one place in the cell, which increases the
rate of polymerization
(d) Fruit fly DNA contains more origins of replication
than E coli DNA.
6. True or false? False. This is accomplished
When DNA is being replicated inside a cell, local heat- by initiated proteins bind-
ing occurs, allowing the two strands to separate. ing at the origin of replica-
tion.
7. True or false? They are rich in A-T base
DNA replication origins are typically rich in G-C base pairs which makes it easier
pairs. for them to separate the
strands because they are
only held together by two
hydrogen bonds
8. True or false? true
Meselson and Stahl ruled out the dispersive model for
DNA replication.
9. True or false? True
DNA replication is a bidirectional process that is ini-
tiated at multiple locations among chromosomes in
eukaryotic cells.