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ISSA Final Exam Study Guide | Certified Personal Trainer Exam Prep & Practice Questions 2026

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Prepare for the ISSA Certified Personal Trainer (CPT) Final Exam with this comprehensive study guide, designed to strengthen knowledge retention and improve exam performance through structured review and practice questions. This guide covers core ISSA certification domains, including exercise science, anatomy and physiology, biomechanics, kinesiology, nutrition, weight management, client assessment, fitness testing, program design, resistance training, cardiovascular conditioning, flexibility training, recovery strategies, special populations, behavior change, and professional ethics.

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📚 ISSA ISSA Final Exam Study Guide
SECTION 1: Anatomy & Physiology
(Questions 1–30)
1. Which three levels of organization make up the basic structure of the
human body?

Answer: Chemicals, cells, and tissues

2. What are the two major processes that make up metabolism?

Answer: Catabolism and anabolism

3. What does BMR stand for?

Answer: Basal Metabolic Rate

4. During a 30-minute jog, which energy system supplies most of the
body's energy?

Answer: Oxidative (aerobic) system

5. What is homeostasis?

Answer: The body's ability to maintain a stable internal environment

6. True or False: Approximately 98% of the human body is composed of
oxygen, carbon, hydrogen, nitrogen, calcium, and phosphorus.

Answer: True

7. Which organelle is known as the powerhouse of the cell?

Answer: Mitochondria

8. True or False: The heart, arteries, and veins belong to the circulatory
system.

Answer: True

, 9. True or False: The ATP-CP system is aerobic.

Answer: False

10. How long can non-oxidative glycolysis supply ATP?

Answer: Up to 2 minutes

11. What is the primary fuel source during endurance exercise?

Answer: Fatty acids

12. What are the primary functions of hormones?

Answer: Regulate protein synthesis, enzyme activity, and nutrient transport

13. What is the primary purpose of digestion?

Answer: Break down food and eliminate waste

14. What are the major functions of the respiratory system?

Answer: Supply oxygen, remove carbon dioxide, regulate pH

15. How many bones are in the adult skeleton?

Answer: 206

16. True or False: The axial skeleton contains 80 bones.

Answer: True

17. Which joint allows movement primarily in one plane?

Answer: Hinge joint

18. True or False: Tendons connect bone to bone.

Answer: False

19. What structures connect muscle to bone?

Answer: Tendons

20. What are the two attachment points of a muscle?

Answer: Origin and insertion

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