NR507 ADVANCED PATHOPHYSIOLOGY WEEK 8 EXAM CHAMBERLAIN UNIVERSITY
NR507 ADVANCED PATHOPHYSIOLOGY WEEK
8 EXAM CHAMBERLAIN UNIVERSITY EXAM
QUESTIONS AND ANSWERS WITH RATIONALE
2026
Topics: Gastrointestinal, Hepatic, Pancreatic, Biliary,
Nutritional, and Multisystem Disorders
Focus: Clinical reasoning and pathophysiology.
Questions 1–10
1. A patient with cirrhosis develops ascites. The primary mechanism is:
A. Increased plasma oncotic pressure
B. Portal hypertension and hypoalbuminemia
C. Increased erythropoietin
D. Hypercalcemia
Answer: B
Rationale: Portal hypertension increases hydrostatic pressure while decreased albumin lowers
oncotic pressure.
2. Which laboratory finding is most suggestive of acute hepatocellular injury?
A. Elevated ALT and AST
B. Elevated troponin
C. Elevated BNP
D. Elevated amylase only
Answer: A
, NR507 ADVANCED PATHOPHYSIOLOGY WEEK 8 EXAM CHAMBERLAIN UNIVERSITY
3. Hepatic encephalopathy is primarily caused by accumulation of:
A. Bilirubin
B. Ammonia
C. Glucose
D. Potassium
Answer: B
4. A patient with advanced cirrhosis develops esophageal varices because of:
A. Increased bile production
B. Portal hypertension
C. Hyperglycemia
D. Pancreatitis
Answer: B
5. Which finding is most characteristic of obstructive jaundice?
A. Elevated unconjugated bilirubin only
B. Dark urine and pale stools
C. Increased erythropoiesis
D. Hypernatremia
Answer: B
6. Acute pancreatitis most commonly results from:
A. Gallstones and alcohol use
B. Asthma
C. Hypothyroidism
D. Parkinson disease
Answer: A
7. The primary pathophysiologic event in acute pancreatitis is:
NR507 ADVANCED PATHOPHYSIOLOGY WEEK
8 EXAM CHAMBERLAIN UNIVERSITY EXAM
QUESTIONS AND ANSWERS WITH RATIONALE
2026
Topics: Gastrointestinal, Hepatic, Pancreatic, Biliary,
Nutritional, and Multisystem Disorders
Focus: Clinical reasoning and pathophysiology.
Questions 1–10
1. A patient with cirrhosis develops ascites. The primary mechanism is:
A. Increased plasma oncotic pressure
B. Portal hypertension and hypoalbuminemia
C. Increased erythropoietin
D. Hypercalcemia
Answer: B
Rationale: Portal hypertension increases hydrostatic pressure while decreased albumin lowers
oncotic pressure.
2. Which laboratory finding is most suggestive of acute hepatocellular injury?
A. Elevated ALT and AST
B. Elevated troponin
C. Elevated BNP
D. Elevated amylase only
Answer: A
, NR507 ADVANCED PATHOPHYSIOLOGY WEEK 8 EXAM CHAMBERLAIN UNIVERSITY
3. Hepatic encephalopathy is primarily caused by accumulation of:
A. Bilirubin
B. Ammonia
C. Glucose
D. Potassium
Answer: B
4. A patient with advanced cirrhosis develops esophageal varices because of:
A. Increased bile production
B. Portal hypertension
C. Hyperglycemia
D. Pancreatitis
Answer: B
5. Which finding is most characteristic of obstructive jaundice?
A. Elevated unconjugated bilirubin only
B. Dark urine and pale stools
C. Increased erythropoiesis
D. Hypernatremia
Answer: B
6. Acute pancreatitis most commonly results from:
A. Gallstones and alcohol use
B. Asthma
C. Hypothyroidism
D. Parkinson disease
Answer: A
7. The primary pathophysiologic event in acute pancreatitis is: