ATI Pharmacology Proctored Exam 2026–2027 | Nursing
Pharmacology & Medication Administration | Latest
Comprehensive Practice Questions with Verified Correct
Answers & Explainations | ATI RN Exam Prep Study Guide |
A+ Graded Success Bundle
THIS EXAM INCLUDES:
✅ Comprehensive ATI Pharmacology Proctored Exam study guide aligned with current nursing pharmacology
concepts
✅ Extensive collection of ATI-style practice questions covering major pharmacology topics tested in nursing
programs
✅ Verified correct answers with detailed rationales to strengthen understanding and clinical judgment
✅ Review of pharmacokinetics, pharmacodynamics, medication administration principles, and medication
safety standards
✅ In-depth coverage of cardiovascular, respiratory, endocrine, neurological, gastrointestinal, psychiatric, and
anti-infective medications
✅ Essential nursing considerations for medication administration, monitoring, contraindications, adverse
effects, and patient education
,ATI Nursing Pharmacology & Medication
Administration
Question 1
A nurse is caring for a client who is to receive treatment for opioid use
disorder. Which of the following medications should the nurse expect to
administer?
A. Bupropion
B. Disulfiram
C. Modafinil
D. Methadone
Explanation: The nurse should expect to administer methadone for
treatment of opioid use disorder. Methadone can be administered for
withdrawal and to assist with maintenance and suppressive therapy.
Question 2
A nurse is caring for a client on a medical-surgical unit with Crohn's disease
exacerbation who has a central venous access device (CVAD) and is
receiving TPN. The TPN bag completed 1 hour ago, and the CVAD is
difficult to flush. The nurse should first address the client's ________ followed
by the client's ________.
A. Pain, Bowel sounds
B. Vitals, Albumin level
,C. Glucose, CVAD
D. Pain, CVAD
Explanation: When analyzing cues, the nurse should identify that the client
is developing hypoglycemia and experiencing a CVAD complication.
Glucose assessment and CVAD patency are priorities.
Question 3
A nurse is preparing to administer hydrochlorothiazide (HCTZ) to a client.
Which of the following actions should the nurse take prior to administering
the medication?
A. Ask the client to drink 8 oz of water
B. Review the client's most recent Hgb level
C. Obtain the client's blood pressure
D. Determine if the client is allergic to NSAIDs
Explanation: HCTZ is a thiazide diuretic administered to promote urine
output and reduce blood pressure and edema. The nurse should obtain the
client's blood pressure prior to administration of the medication.
Question 4
A nurse is planning care for a client who is receiving mannitol via
continuous IV infusion. Which of the following adverse effects should the
nurse monitor the client for?
, A. Weight loss
B. Increased intraocular pressure
C. Auditory hallucinations
D. Bibasilar crackles
Explanation: Mannitol, an osmotic diuretic, can precipitate heart failure
and pulmonary edema. Therefore, the nurse should recognize lung crackles
as an indicator of a potential complication and stop the infusion.
Question 5
A nurse is caring for a client who is taking nitroglycerin for angina and
reports feeling faint when standing up. Which of the following actions
should the nurse take?
A. Inform the client that feeling faint is caused by rapid constriction of
blood vessels in the legs
B. Assist the client into bed, elevate the lower extremities, and check
their blood pressure
C. Request a prescription for dobutamine from the client's provider
D. Check the client's blood pressure while they're still standing
Explanation: The nurse should first assist the client into bed to prevent
injuries from a fall. The nurse should elevate the client's legs on pillows to
enhance venous return from the lower extremities. The nurse should then
check the client's blood pressure.
Pharmacology & Medication Administration | Latest
Comprehensive Practice Questions with Verified Correct
Answers & Explainations | ATI RN Exam Prep Study Guide |
A+ Graded Success Bundle
THIS EXAM INCLUDES:
✅ Comprehensive ATI Pharmacology Proctored Exam study guide aligned with current nursing pharmacology
concepts
✅ Extensive collection of ATI-style practice questions covering major pharmacology topics tested in nursing
programs
✅ Verified correct answers with detailed rationales to strengthen understanding and clinical judgment
✅ Review of pharmacokinetics, pharmacodynamics, medication administration principles, and medication
safety standards
✅ In-depth coverage of cardiovascular, respiratory, endocrine, neurological, gastrointestinal, psychiatric, and
anti-infective medications
✅ Essential nursing considerations for medication administration, monitoring, contraindications, adverse
effects, and patient education
,ATI Nursing Pharmacology & Medication
Administration
Question 1
A nurse is caring for a client who is to receive treatment for opioid use
disorder. Which of the following medications should the nurse expect to
administer?
A. Bupropion
B. Disulfiram
C. Modafinil
D. Methadone
Explanation: The nurse should expect to administer methadone for
treatment of opioid use disorder. Methadone can be administered for
withdrawal and to assist with maintenance and suppressive therapy.
Question 2
A nurse is caring for a client on a medical-surgical unit with Crohn's disease
exacerbation who has a central venous access device (CVAD) and is
receiving TPN. The TPN bag completed 1 hour ago, and the CVAD is
difficult to flush. The nurse should first address the client's ________ followed
by the client's ________.
A. Pain, Bowel sounds
B. Vitals, Albumin level
,C. Glucose, CVAD
D. Pain, CVAD
Explanation: When analyzing cues, the nurse should identify that the client
is developing hypoglycemia and experiencing a CVAD complication.
Glucose assessment and CVAD patency are priorities.
Question 3
A nurse is preparing to administer hydrochlorothiazide (HCTZ) to a client.
Which of the following actions should the nurse take prior to administering
the medication?
A. Ask the client to drink 8 oz of water
B. Review the client's most recent Hgb level
C. Obtain the client's blood pressure
D. Determine if the client is allergic to NSAIDs
Explanation: HCTZ is a thiazide diuretic administered to promote urine
output and reduce blood pressure and edema. The nurse should obtain the
client's blood pressure prior to administration of the medication.
Question 4
A nurse is planning care for a client who is receiving mannitol via
continuous IV infusion. Which of the following adverse effects should the
nurse monitor the client for?
, A. Weight loss
B. Increased intraocular pressure
C. Auditory hallucinations
D. Bibasilar crackles
Explanation: Mannitol, an osmotic diuretic, can precipitate heart failure
and pulmonary edema. Therefore, the nurse should recognize lung crackles
as an indicator of a potential complication and stop the infusion.
Question 5
A nurse is caring for a client who is taking nitroglycerin for angina and
reports feeling faint when standing up. Which of the following actions
should the nurse take?
A. Inform the client that feeling faint is caused by rapid constriction of
blood vessels in the legs
B. Assist the client into bed, elevate the lower extremities, and check
their blood pressure
C. Request a prescription for dobutamine from the client's provider
D. Check the client's blood pressure while they're still standing
Explanation: The nurse should first assist the client into bed to prevent
injuries from a fall. The nurse should elevate the client's legs on pillows to
enhance venous return from the lower extremities. The nurse should then
check the client's blood pressure.
