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ANCC IQ Domain 1 Exam Questions with Correct Answers 2026 | Scientific Foundation Certification Prep

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Pass your ANCC IQ Domain 1: Scientific Foundation exam with this 2026 question bank featuring verified correct answers. Covers neurobiology, psychopharmacology (tardive dyskinesia, NMS, lamotrigine, disulfiram, trazodone, citalopram), pathophysiology (anemia, Type 2 diabetes, diabetic neuropathy, chronic stress, IL-6, troponin, RAAS, cystic fibrosis ΔF508), neurodevelopment (prefrontal cortex, Asperger's), endocrinology (cortisol, HPA axis), psychological theories, and cellular mechanisms. Ideal for PMHNP-BC and FNP-BC candidates.

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, ANCC IQ DOMAIN 1 EXAM QUESTIONS WITH
CORRECT ANSWERS 2026

As a PMHNP, you are aware of antipsychotic medication side effects. Which of the following side
effects of antipsychotic medications has an insidious, delayed-onset typically 1 to 2 years after
initiation of the medication?

a. Dry mouth

b. Tardive dyskinesia

c. Sedation

d. Weight gain - CORRECT ANSWER -B



In evaluating a 4-year-old, one would expect which of the following delays in Asperger's
Disorder?

a. Language development

b. Cognitive development

c. Motor skills coordination

d. Social skills development - CORRECT ANSWER -D



Which area of the brain has been implicated to modulate pain and can help explain how
transcranial magnetic stimulation can help decrease pain?

a. Prefrontal cortex

b. Insula cortex

c. Dorsolateral prefrontal cortex

d. Anterior cingulate cortex - CORRECT ANSWER -A



Which of the following antidepressants is associated with dose-related cardiovascular adverse
effects which require adherence to maximum recommended dosing, unless higher doses are
deemed appropriate despite risks?

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