RACP exam questions Exam questions and
verified answers (complete solutions) GRADE A
Save
Terms in this set (167)
.Treatment of oestrogen-receptor G1 (cells that cease cell divison)
positive breast cancer with tamoxifen
causes cells to accumulate in which
cell cycle phase?
A. G0
B. G1
C. G2
D. M
E. S
A 68 y/o man with RA for 15yrs has C. Osteophytes
the following bone densitometry Osteophytes, compression fracture, aortic calcif,
results on DEXA ank spond = falsely raise bone score
lumbar spine T +1.3 Z +2
femoral T -2.4 Z -1.7
What is the most likely explanation
for discrepancy between fem neck
and lumbar spine?
A. Metastatic bone disease
B. Osteonecrosis of hip
C. osteophyte in lumbar spine
D. pagets in lumbar spine
E. synovitis in hip
,What drug of addiction stimulates A. alcohol (stim GABA-A, inhibits glut)
GABA-A receptors?
A. alcohol cocaine - stops dopamine removal
B. cocaine , 5HT agonist
C. heroin heroin - opioid agonist
D. methamphetamine metham - dop and norad agonist
E. nicotine nicotine - nicotine receptors on dop
Decrease in which factor will cause R CADET turn right
shift in oxygen dissociation curve? = increased CO2, acid, DPG, exercise, temp
A 23DPG
B. CO2 so D = decreased pH aka more acid
C. Hb
D. pH
E. temp
In evaluating pt with suspected E
kidney disease, the use of urine Preferentially detects albumin. Less sensitive to
dipstick may fail to detect significant globulins/heavy or light chains
quantities of which?
A. albumin
B. erythrocytes
C. leucocytes
D. nitrites
E. non albumin protein
The in vitro gamma IFN release assay A. detects exposure
Quantiferon Gold is commonly used Highly specific, but low sens
in pts with suspected myco TB. What Can't diff active vs latent
is the main role of Quant Gold test? Need at least 8w post-exposure
A. detect exposure to MTB
B. determine extent of MTB
C. determine response of MTB to rx
D. predict active MTB
E. rule out MTB
,Initiation of inflammation in acute B. IL 1 beta. (canakinumab targets)
gout is critically dependent on which
cytokine? IFN gamma: TB, granulomas
A. IFN gamma IL13: allergic airways
B. IL1B IL 17: PsA, RA, AS
C. IL13 TNF: PsA, RA, UC, Crohn's
D. IL17
E. TNF
OSA is assoc. with increased B: hypoxia/hypercapnia = sympathetic surge (+
prevalence of systemic HTN. What is reduced vagal tone)
the predominant mechanism for this?
A. increased CO E - hypercapnia = vasodil
B. increased sympathetic tone
C. resetting of renal pressure
natriuresis
D: upregulation of carotid
chemoreceptor sensitivity
E: vasoconstriction secondary to
intermittent hypercapnia
Which 1 of the following is a minor C
citerion for acute rheumatic fever?
A. carditis Major: carditis, polyarthritis, chorea, erythema
B. polyarthritis marginatum, subcut nodules
C. prolonged PR interval Minor: fever, polyarthralgia, ESR/CRP, prolonged
D. proteinuria PR (unless carditis is major)
E. subcutaneous nodules + supporting evidence of GAS
2 maj, or 1 maj, 2 minor
, In a RCT the time from recruitment to D. Relative risk ?? vs Hazard ratio
1st cardiovascular event is measured.
What is the best term to express the
result?
A. Hazard ratio
B. incidence rate
C. odds ratio
D. RR
E. risk difference
What is the function of BCL2 protein? D. antiapoptoptic
A. Activates cell death
B. activates cell survival
C. activates effector caspases
D. inhibits cell apoptotic proteins
E. inhibits cell survival proteins
By which mechanism does E. beta adrenoreceptor agonist
dobutamine predominantly increase
CO?
A. Activation of cell surface dop Rs
B. inhibition of alpha-
adrenoreceptors
C. reduction in breakdown of cAMP
D. relaxation of vasc smooth muscle
E. stimulation of beta
adrenoreceptors
NMDA receptors are activated by B. NMDA is a glutamate receptor activated when
which of the following? glycine and glutamate bind to it
A. dopamine Ie. NMDA R antag = used in dementia (dementia =
B. glutamate low glutamate/excitatory)
C. melatonin
D. noradrenaline
E. serotonin
verified answers (complete solutions) GRADE A
Save
Terms in this set (167)
.Treatment of oestrogen-receptor G1 (cells that cease cell divison)
positive breast cancer with tamoxifen
causes cells to accumulate in which
cell cycle phase?
A. G0
B. G1
C. G2
D. M
E. S
A 68 y/o man with RA for 15yrs has C. Osteophytes
the following bone densitometry Osteophytes, compression fracture, aortic calcif,
results on DEXA ank spond = falsely raise bone score
lumbar spine T +1.3 Z +2
femoral T -2.4 Z -1.7
What is the most likely explanation
for discrepancy between fem neck
and lumbar spine?
A. Metastatic bone disease
B. Osteonecrosis of hip
C. osteophyte in lumbar spine
D. pagets in lumbar spine
E. synovitis in hip
,What drug of addiction stimulates A. alcohol (stim GABA-A, inhibits glut)
GABA-A receptors?
A. alcohol cocaine - stops dopamine removal
B. cocaine , 5HT agonist
C. heroin heroin - opioid agonist
D. methamphetamine metham - dop and norad agonist
E. nicotine nicotine - nicotine receptors on dop
Decrease in which factor will cause R CADET turn right
shift in oxygen dissociation curve? = increased CO2, acid, DPG, exercise, temp
A 23DPG
B. CO2 so D = decreased pH aka more acid
C. Hb
D. pH
E. temp
In evaluating pt with suspected E
kidney disease, the use of urine Preferentially detects albumin. Less sensitive to
dipstick may fail to detect significant globulins/heavy or light chains
quantities of which?
A. albumin
B. erythrocytes
C. leucocytes
D. nitrites
E. non albumin protein
The in vitro gamma IFN release assay A. detects exposure
Quantiferon Gold is commonly used Highly specific, but low sens
in pts with suspected myco TB. What Can't diff active vs latent
is the main role of Quant Gold test? Need at least 8w post-exposure
A. detect exposure to MTB
B. determine extent of MTB
C. determine response of MTB to rx
D. predict active MTB
E. rule out MTB
,Initiation of inflammation in acute B. IL 1 beta. (canakinumab targets)
gout is critically dependent on which
cytokine? IFN gamma: TB, granulomas
A. IFN gamma IL13: allergic airways
B. IL1B IL 17: PsA, RA, AS
C. IL13 TNF: PsA, RA, UC, Crohn's
D. IL17
E. TNF
OSA is assoc. with increased B: hypoxia/hypercapnia = sympathetic surge (+
prevalence of systemic HTN. What is reduced vagal tone)
the predominant mechanism for this?
A. increased CO E - hypercapnia = vasodil
B. increased sympathetic tone
C. resetting of renal pressure
natriuresis
D: upregulation of carotid
chemoreceptor sensitivity
E: vasoconstriction secondary to
intermittent hypercapnia
Which 1 of the following is a minor C
citerion for acute rheumatic fever?
A. carditis Major: carditis, polyarthritis, chorea, erythema
B. polyarthritis marginatum, subcut nodules
C. prolonged PR interval Minor: fever, polyarthralgia, ESR/CRP, prolonged
D. proteinuria PR (unless carditis is major)
E. subcutaneous nodules + supporting evidence of GAS
2 maj, or 1 maj, 2 minor
, In a RCT the time from recruitment to D. Relative risk ?? vs Hazard ratio
1st cardiovascular event is measured.
What is the best term to express the
result?
A. Hazard ratio
B. incidence rate
C. odds ratio
D. RR
E. risk difference
What is the function of BCL2 protein? D. antiapoptoptic
A. Activates cell death
B. activates cell survival
C. activates effector caspases
D. inhibits cell apoptotic proteins
E. inhibits cell survival proteins
By which mechanism does E. beta adrenoreceptor agonist
dobutamine predominantly increase
CO?
A. Activation of cell surface dop Rs
B. inhibition of alpha-
adrenoreceptors
C. reduction in breakdown of cAMP
D. relaxation of vasc smooth muscle
E. stimulation of beta
adrenoreceptors
NMDA receptors are activated by B. NMDA is a glutamate receptor activated when
which of the following? glycine and glutamate bind to it
A. dopamine Ie. NMDA R antag = used in dementia (dementia =
B. glutamate low glutamate/excitatory)
C. melatonin
D. noradrenaline
E. serotonin
