Protein Turnover and
degradation
Lecture 20
By: Dr. Maria Fazal-Ul-Haq
, Protein Turnover and degradation
* Protein turnover is a balance between protein resynthesis and protein
degradation.
* Protein synthesis is done by translation that is dynamic process that
involves the interaction of enzymes, tRNA, ribosomes and rRNAs,
translation factors and mRNA.
* Faulty or damaged proteins are recognized and degraded within cells,
by eliminating the mistakes made during protein synthesis.
* Proteins are constantly being degraded and resynthesized.
5/22/2026 Dr. Maria Fazal-Ul-Haq 2
degradation
Lecture 20
By: Dr. Maria Fazal-Ul-Haq
, Protein Turnover and degradation
* Protein turnover is a balance between protein resynthesis and protein
degradation.
* Protein synthesis is done by translation that is dynamic process that
involves the interaction of enzymes, tRNA, ribosomes and rRNAs,
translation factors and mRNA.
* Faulty or damaged proteins are recognized and degraded within cells,
by eliminating the mistakes made during protein synthesis.
* Proteins are constantly being degraded and resynthesized.
5/22/2026 Dr. Maria Fazal-Ul-Haq 2