ASCP HEMATOLOGY EXAM STUDY SHEET
2026 UPDATED QUESTIONS AND
SOLUTIONS
◉ Target cells are commonly seen in what condition(s)?
Answer: liver disease, Hb C, thalassemia, other hemoglobinopathies
◉ Helmet cells are seen in what condition(s)?
Answer: hemolytic processes
◉ Another name for helmet cells is?
Answer: keratocyte
◉ Teardrop drop cells are seen in what condition(s)?
Answer: extramedullary hematopoiesis, thalassemias, pernicious
anemia
◉ Schistocytes are seen in what condition(s)?
Answer: DIC, hemolytic processes
◉ Howell-Jolly bodies are composed of?
,Answer: DNA
◉ What condition(s) are howell-jolly bodies seen in?
Answer: disturbed erythropoiesis, hemolytic anemias, megaloblastic
anemia, post-splenectomy
◉ The inclusions seen in basophilic stippling are composed of?
Answer: RNA
◉ What condition(s) is basophilic stippling seen in?
Answer: thalassemia, lead poisoning
◉ What stains are utilized to see basophilic stippling?
Answer: wright, new methyene blue
◉ Pappenheimer bodies are composed of?
Answer: iron
◉ What stains are utilized to see pappenheimer bodies?
Answer: wright, prussian blue
◉ What conditions are pappenhemier bodies seen in?
, Answer: sideroblastic anemia, hemoglobinopathies
◉ What are heinz bodies composed of?
Answer: denatured precipitated hemoglobin
◉ What stain can you NOT see heinz bodies? What stain is used
instead?
Answer: Wright, supravital stain (brilliant cresyl blue/new
methylene blue)
◉ What conditions are heinz bodies seen in?
Answer: G6PD deficiency, thalassemia, unstable hemoglobins
◉ What are cabot rings composed of?
Answer: remnants of the mitotic spindle
◉ What conditions are cabot rings seen in?
Answer: megaloblastic anemia
◉ How does the value for hemoglobin compare to the value for the
hematocrit?
Answer: Hgb X 3 = Hct +/-3%
2026 UPDATED QUESTIONS AND
SOLUTIONS
◉ Target cells are commonly seen in what condition(s)?
Answer: liver disease, Hb C, thalassemia, other hemoglobinopathies
◉ Helmet cells are seen in what condition(s)?
Answer: hemolytic processes
◉ Another name for helmet cells is?
Answer: keratocyte
◉ Teardrop drop cells are seen in what condition(s)?
Answer: extramedullary hematopoiesis, thalassemias, pernicious
anemia
◉ Schistocytes are seen in what condition(s)?
Answer: DIC, hemolytic processes
◉ Howell-Jolly bodies are composed of?
,Answer: DNA
◉ What condition(s) are howell-jolly bodies seen in?
Answer: disturbed erythropoiesis, hemolytic anemias, megaloblastic
anemia, post-splenectomy
◉ The inclusions seen in basophilic stippling are composed of?
Answer: RNA
◉ What condition(s) is basophilic stippling seen in?
Answer: thalassemia, lead poisoning
◉ What stains are utilized to see basophilic stippling?
Answer: wright, new methyene blue
◉ Pappenheimer bodies are composed of?
Answer: iron
◉ What stains are utilized to see pappenheimer bodies?
Answer: wright, prussian blue
◉ What conditions are pappenhemier bodies seen in?
, Answer: sideroblastic anemia, hemoglobinopathies
◉ What are heinz bodies composed of?
Answer: denatured precipitated hemoglobin
◉ What stain can you NOT see heinz bodies? What stain is used
instead?
Answer: Wright, supravital stain (brilliant cresyl blue/new
methylene blue)
◉ What conditions are heinz bodies seen in?
Answer: G6PD deficiency, thalassemia, unstable hemoglobins
◉ What are cabot rings composed of?
Answer: remnants of the mitotic spindle
◉ What conditions are cabot rings seen in?
Answer: megaloblastic anemia
◉ How does the value for hemoglobin compare to the value for the
hematocrit?
Answer: Hgb X 3 = Hct +/-3%
