Pioglitazone (Actos)
Give this one a try later!
Glitazone
Decrease insulin resistance by activating insulin-responsive genes (usually
add on to metformin or sulfonylurea)
CI: HF, bladder cancer, undiagnosed edema/SOB
AE: HF, fractures, ovulation (teach BC)
BBW: d/c or use decreased dosage in patients with HF
Metoprolol (Lopressor)
Give this one a try later!
, 2nd line tx HTN
Selective B-adrenergic blocker (B1)
Selectively inhibits B1 (heart)
Preferred agent in lung dz (less likely to cause bronchospasm)
CI: bradycardia, cardiogenic shock
AE: fatigue, insomnia, MASK HYPOGLYCEMIC S/S, decreased libido
BBW: don't stop abruptly due to angina and possible MI
Interactions: amiodarone enhance bradycardia, hypoglycemia enhanced
with diabetic meds
-LoL
Low HR
Low BP
Neg chronotropic: lower rate—-> decreases resistance
Neg inotropic: less force —-> decreases workload
Neg dromotropic: less beats —-> decreases CO
BBBB
Bradycardia
Breathing problems (Not Metoprolol d/t selectivity)
Bad for HF patients
New edema, crackles in the lungs, rapid weight gain
Blood sugar masking
Aliskiren (Tekturna)
Give this one a try later!
Direct Renin Inhibitor
Binds to renin inhibiting the process of conversion of angiotensinogen to
angiotensin I
Influences entire RAAS
CI: pregnancy
AE: Diarrhea with high doses, (& similar effects to ACE-Is/ARBs)
BBW: fetal injury and death
Interactions: drugs that increase k (hyperkalemia), high fat meals (decrease
absorption- teaching), grapefruit juice
, Regular insulin (Humulin R)
Give this one a try later!
Short duration: short acting
Onset: 30-60 min
Peak: 1-5 hr
Duration: 6-10 hr
Administration: given before meals to control postprandial rise; provide
basal glycemic control via an Insulin pump
Folic acid
Give this one a try later!
Necessary for formation of coenzymes in metabolic systems (purine and
pyrimidine synthesis), required for nucleoprotein synthesis and
maintenance erythropoiesis, stimulates WBC and PLT production in folate
deficiency anemia
Prophylactic use in pregnancy, folic acid deficiency
Oral preferred (0.4, 0.8, 1 mg tablets), start 1-5 mg daily, maintenance 400
mcg daily
AE: flushing, malaise, skin rash
above 60
Give this one a try later!
goal HDL level
Give this one a try later!
Glitazone
Decrease insulin resistance by activating insulin-responsive genes (usually
add on to metformin or sulfonylurea)
CI: HF, bladder cancer, undiagnosed edema/SOB
AE: HF, fractures, ovulation (teach BC)
BBW: d/c or use decreased dosage in patients with HF
Metoprolol (Lopressor)
Give this one a try later!
, 2nd line tx HTN
Selective B-adrenergic blocker (B1)
Selectively inhibits B1 (heart)
Preferred agent in lung dz (less likely to cause bronchospasm)
CI: bradycardia, cardiogenic shock
AE: fatigue, insomnia, MASK HYPOGLYCEMIC S/S, decreased libido
BBW: don't stop abruptly due to angina and possible MI
Interactions: amiodarone enhance bradycardia, hypoglycemia enhanced
with diabetic meds
-LoL
Low HR
Low BP
Neg chronotropic: lower rate—-> decreases resistance
Neg inotropic: less force —-> decreases workload
Neg dromotropic: less beats —-> decreases CO
BBBB
Bradycardia
Breathing problems (Not Metoprolol d/t selectivity)
Bad for HF patients
New edema, crackles in the lungs, rapid weight gain
Blood sugar masking
Aliskiren (Tekturna)
Give this one a try later!
Direct Renin Inhibitor
Binds to renin inhibiting the process of conversion of angiotensinogen to
angiotensin I
Influences entire RAAS
CI: pregnancy
AE: Diarrhea with high doses, (& similar effects to ACE-Is/ARBs)
BBW: fetal injury and death
Interactions: drugs that increase k (hyperkalemia), high fat meals (decrease
absorption- teaching), grapefruit juice
, Regular insulin (Humulin R)
Give this one a try later!
Short duration: short acting
Onset: 30-60 min
Peak: 1-5 hr
Duration: 6-10 hr
Administration: given before meals to control postprandial rise; provide
basal glycemic control via an Insulin pump
Folic acid
Give this one a try later!
Necessary for formation of coenzymes in metabolic systems (purine and
pyrimidine synthesis), required for nucleoprotein synthesis and
maintenance erythropoiesis, stimulates WBC and PLT production in folate
deficiency anemia
Prophylactic use in pregnancy, folic acid deficiency
Oral preferred (0.4, 0.8, 1 mg tablets), start 1-5 mg daily, maintenance 400
mcg daily
AE: flushing, malaise, skin rash
above 60
Give this one a try later!
goal HDL level
