Cardiovascular Pharmacology Master Guide
ACE Inhibitors, ARBs, Beta Blockers, Loop Diuretics, Spironolactone,
Digoxin, and Nitrates
This is a high-yield RN/NCLEX-style pharmacology review focused on:
Generic drug names
Mechanism of action (MOA)
Therapeutic response
Must-know adverse effects
Nursing monitoring
Patient teaching
1. ACE InHIBITORS (Angiotensin-Converting Enzyme Inhibitors)
Common Generic Drugs
lisinopril
enalapril
captopril
ramipril
benazepril
MOA
ACE inhibitors block the conversion of angiotensin I to angiotensin II.
This causes:
, vasodilation
decreased blood pressure
decreased aldosterone secretion
decreased sodium and water retention
reduced cardiac workload
Key NCLEX Phrase
“Prevents vasoconstriction and fluid retention.”
Therapeutic Response
Used for:
hypertension
heart failure
diabetic nephropathy
post-MI protection
kidney protection in diabetes
Expected findings:
lower BP
decreased edema
improved cardiac output
decreased proteinuria
, Must-Know Adverse Effects
HIGH YIELD
dry persistent cough
hyperkalemia
hypotension
dizziness
angioedema (EMERGENCY)
acute kidney injury
Why cough occurs
ACE inhibitors increase bradykinin levels.
Monitoring
BP
potassium
BUN/Creatinine
renal function
signs of angioedema
Patient Teaching
Change positions slowly
Avoid potassium supplements/salt substitutes
ACE Inhibitors, ARBs, Beta Blockers, Loop Diuretics, Spironolactone,
Digoxin, and Nitrates
This is a high-yield RN/NCLEX-style pharmacology review focused on:
Generic drug names
Mechanism of action (MOA)
Therapeutic response
Must-know adverse effects
Nursing monitoring
Patient teaching
1. ACE InHIBITORS (Angiotensin-Converting Enzyme Inhibitors)
Common Generic Drugs
lisinopril
enalapril
captopril
ramipril
benazepril
MOA
ACE inhibitors block the conversion of angiotensin I to angiotensin II.
This causes:
, vasodilation
decreased blood pressure
decreased aldosterone secretion
decreased sodium and water retention
reduced cardiac workload
Key NCLEX Phrase
“Prevents vasoconstriction and fluid retention.”
Therapeutic Response
Used for:
hypertension
heart failure
diabetic nephropathy
post-MI protection
kidney protection in diabetes
Expected findings:
lower BP
decreased edema
improved cardiac output
decreased proteinuria
, Must-Know Adverse Effects
HIGH YIELD
dry persistent cough
hyperkalemia
hypotension
dizziness
angioedema (EMERGENCY)
acute kidney injury
Why cough occurs
ACE inhibitors increase bradykinin levels.
Monitoring
BP
potassium
BUN/Creatinine
renal function
signs of angioedema
Patient Teaching
Change positions slowly
Avoid potassium supplements/salt substitutes