Pharmacology HESI V2 Exam Newest 2026
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A client is prescribed phenobarbital ANS: A
sodium (Luminal) for a seizure Medication with long half-lives remain at their
disorder. The medication has a long therapeutic levels between doses for long periods
half-life of 4 days. Based on this half- of time. Therefore, this medication can be
life, the medication will most likely administered once a day.
be prescribed
A. once a day.
B. twice a day.
C. three times a day.
D. four times a day.
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A nurse educator is reviewing ANS: C, E
medication dosages and factors that Liver failure decreases metabolism and thus
influence medication metabolism increase the concentration of medication. This may
with a group of nurses. Medication require decreasing the dosage of medication.
dosages may need to be decreased When two medications are metabolized in the
for which of the following reasons? same way, they may compete for metabolism,
(Select all that apply.) thereby increasing the concentration of one or
A. Increased renal excretion both medications.
B. Increased medication-
metabolizing enzymes Increased renal excretion may decrease
C. Liver failure concentration of the medication, requiring
D. Peripheral vascular disease increased dosage. Increased medication-
E. Concurrent use of medication metabolizing enzymes can decrease the
metabolized by the same pathway concentration of the medication. The dose might
need increased. Peripheral vascular disease may
impair distribution, and more of the medication
may be needed.
A nurse s preparing to administer ANS:B, D, E
eye drops to a client. Which of the The medication should be dropped into the center
following are appropriate nursing of the conjunctival sac to promote better
interventions related to this distribution of the medication. The client should
procedure? (Select all that apply.) close the eye gently to allow improved distribution
A. Using medical aseptic technique of the medication.
B. Asking the client to look up at the
ceiling Surgical aseptic technique is used to administer
C. Having the client lie in a side-lying eye drops. The client should be sitting or in a
position supine position to facilitate proper administration
D. Dropping medication into the of eye drops.
center of the client's conjunctival sac
E. Instructing the client to close the
eye gently
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A nurse is completing discharge ANS: C
teaching to a client who has a new Transdermal medication should be applied to a
prescription for a transdermal hairless area of skin to promote absorption of
medication. Which of the following medication.
statements by the client indicates
understanding of the teaching? The skin should be washed with soap and water
A. "I will clean the site with an and dried thoroughly before applying a
alcohol swab prior to applying the transdermal patch. Application sites should be
patch." rotated on a daily basis to prevent skin irritation.
B. "I will rotate the application site
weekly."
C. "I will apply the patch to an area
of skin with no hair."
D. "I will place the new patch on the
site of the old patch."
A nurse is reviewing a client's health ANS: A
record and notes a new prescription To verify trough levels of a medication, a blood
by the provider to verify the trough specimen is obtained immediately before the next
level of the client's medication. dose of medication.
Which of the following actions
should the nurse take?
A. Have a blood specimen obtained
immediately prior to the next dose of
medication.
B. Verify that the client has been on
the medication for 24 hr before
ordering a blood specimen.
C. Ask the client to provide a urine
specimen after the next dose of
medication.
D. Begin administering the
medication, and obtain a blood
specimen.
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A nurse is preparing a client's ANS: A, C, D
medication. Which of the following Determining medication dosage and identifying a
are legal responsibilities of the diagnosis is the role/responsibility of the provider.
nurse? (Select all that apply.) The nurse should be informed about a client's
A. Maintaining skill competency diagnosis.
B. Determining the dosage
C. Monitoring for adverse effects
D. Safeguarding medications
E. Identifying the client's diagnosis
A nurse is reviewing a client's health ANS: C
record and notes a new prescription A routine prescription identifies a medication that is
by the provider for lisinopril (Zestril) given on a regular schedule. This medication is
10 mg PO every day. The nurse administered every day until discontinued.
should recognize this as which of the
following types of prescription? A single prescription is to be given once at a
A. Single prescription specified time or as soon as possible. A stat
B. Stat prescription prescription is only given once, and it is given
C. Routine prescription immediately. A standing prescription is written for
D. Standing prescription specific circumstances or a specific unit.
A nurse is reviewing a new ANS: D
prescription for ondansetron The time and frequency of medication
(Zofran) 4 mg PO PRN nausea and administration is not included and should be
vomiting for a client who has clarified with the provider.
hyperemesis gravidarum. The nurse
should clarify which of the following
parts of the prescription with the
provider?
A. Name
B. Dosage
C. Route
D. Time
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