1
100 Barkley-Style Practice Questions with Answers and
Evidence-Based Rationales for the AANP Family Nurse
Practitioner (FNP) Certification Examination
AANP FNP Certification Practice Questions (100 Questions)
Health Promotion & Screening (Questions 1–10)
1. According to USPSTF guidelines, at what age should average-risk
adults begin colorectal cancer screening?
A. 40
B. 45
C. 50
D. 55
: Answer : B
Rationale: USPSTF recommends starting screening at age 45 for
average-risk individuals. Options C and D are outdated; A is too early
unless higher risk.
2. A 55-year-old woman with no chronic conditions asks about the
pneumococcal vaccine. Which statement is correct?
A. Only PPSV23 is indicated after age 65.
B. She should receive a single dose of PCV13 now.
C. Both PCV13 and PPSV23 are recommended.
D. No pneumococcal vaccine is needed until age 65.
: Answer : D
Rationale: For immunocompetent adults <65, routine pneumococcal
vaccination begins at age 65 with PCV13 followed by PPSV23. She does
not need it now unless she has a high-risk condition.
pg. 1
,2
3. A 32-year-old woman is due for her first Pap smear. She received
the HPV vaccine at age 16. What is the recommended screening
interval for cervical cancer in average-risk women?
A. Annually
B. Every 3 years with cytology alone
C. Every 5 years with HPV testing alone
D. Every 5 years with co-testing (Pap + HPV) or every 3 years with Pap
alone
: Answer : D
Rationale: For ages 30–65, USPSTF recommends screening every 3 years
with Pap alone or every 5 years with co-testing. Option D reflects that; B
is for ages 21–29, but the patient is 32. The question is unclear, but D is
best for her age.
4. The U.S. Preventive Services Task Force recommends one-time
abdominal aortic aneurysm screening for men aged 65–75 who have
ever smoked. This is an example of:
A. Primary prevention
B. Secondary prevention
C. Tertiary prevention
D. Quaternary prevention
: Answer : B
Rationale: Screening for a disease before symptoms occur is secondary
prevention. Primary is preventing disease (e.g., immunizations), tertiary
is reducing complications.
5. A 70-year-old female patient asks about breast cancer screening.
She has no family history. What is the USPSTF recommendation?
A. Annual mammography starting at 40
B. Mammography every 2 years from age 50 to 74
C. MRI annually
D. No screening after 70
pg. 2
, 3
: Answer : B
Rationale: USPSTF recommends biennial mammography for women
aged 50–74; decision to start earlier is individual. Option A is not
USPSTF; MRI is for high-risk.
6. An 11-year-old girl presents for a well visit. Which vaccines are
recommended at this age?
A. Tdap, HPV, meningococcal conjugate
B. MMR, varicella, hepatitis A
C. Only influenza annually
D. Pneumococcal polysaccharide
: Answer : A
Rationale: At 11–12 years, routine immunizations include Tdap booster,
HPV series, and meningococcal conjugate vaccine (MenACWY).
7. A 45-year-old man with hypertension asks about aspirin for primary
prevention of cardiovascular disease. According to current guidelines,
aspirin should be:
A. Routinely recommended for all men over 40
B. Considered only if 10-year ASCVD risk ≥10% and no increased
bleeding risk
C. Never used for primary prevention
D. Given only if he has diabetes
: Answer : B
Rationale: The USPSTF recommends low-dose aspirin for primary
prevention in adults 40-59 years with ≥10% 10-year ASCVD risk, after
shared decision-making. It's not routine for all.
8. A mother brings her 4-month-old infant for well-child care. Which
vaccine should the infant receive today?
A. MMR
B. Varicella
pg. 3
100 Barkley-Style Practice Questions with Answers and
Evidence-Based Rationales for the AANP Family Nurse
Practitioner (FNP) Certification Examination
AANP FNP Certification Practice Questions (100 Questions)
Health Promotion & Screening (Questions 1–10)
1. According to USPSTF guidelines, at what age should average-risk
adults begin colorectal cancer screening?
A. 40
B. 45
C. 50
D. 55
: Answer : B
Rationale: USPSTF recommends starting screening at age 45 for
average-risk individuals. Options C and D are outdated; A is too early
unless higher risk.
2. A 55-year-old woman with no chronic conditions asks about the
pneumococcal vaccine. Which statement is correct?
A. Only PPSV23 is indicated after age 65.
B. She should receive a single dose of PCV13 now.
C. Both PCV13 and PPSV23 are recommended.
D. No pneumococcal vaccine is needed until age 65.
: Answer : D
Rationale: For immunocompetent adults <65, routine pneumococcal
vaccination begins at age 65 with PCV13 followed by PPSV23. She does
not need it now unless she has a high-risk condition.
pg. 1
,2
3. A 32-year-old woman is due for her first Pap smear. She received
the HPV vaccine at age 16. What is the recommended screening
interval for cervical cancer in average-risk women?
A. Annually
B. Every 3 years with cytology alone
C. Every 5 years with HPV testing alone
D. Every 5 years with co-testing (Pap + HPV) or every 3 years with Pap
alone
: Answer : D
Rationale: For ages 30–65, USPSTF recommends screening every 3 years
with Pap alone or every 5 years with co-testing. Option D reflects that; B
is for ages 21–29, but the patient is 32. The question is unclear, but D is
best for her age.
4. The U.S. Preventive Services Task Force recommends one-time
abdominal aortic aneurysm screening for men aged 65–75 who have
ever smoked. This is an example of:
A. Primary prevention
B. Secondary prevention
C. Tertiary prevention
D. Quaternary prevention
: Answer : B
Rationale: Screening for a disease before symptoms occur is secondary
prevention. Primary is preventing disease (e.g., immunizations), tertiary
is reducing complications.
5. A 70-year-old female patient asks about breast cancer screening.
She has no family history. What is the USPSTF recommendation?
A. Annual mammography starting at 40
B. Mammography every 2 years from age 50 to 74
C. MRI annually
D. No screening after 70
pg. 2
, 3
: Answer : B
Rationale: USPSTF recommends biennial mammography for women
aged 50–74; decision to start earlier is individual. Option A is not
USPSTF; MRI is for high-risk.
6. An 11-year-old girl presents for a well visit. Which vaccines are
recommended at this age?
A. Tdap, HPV, meningococcal conjugate
B. MMR, varicella, hepatitis A
C. Only influenza annually
D. Pneumococcal polysaccharide
: Answer : A
Rationale: At 11–12 years, routine immunizations include Tdap booster,
HPV series, and meningococcal conjugate vaccine (MenACWY).
7. A 45-year-old man with hypertension asks about aspirin for primary
prevention of cardiovascular disease. According to current guidelines,
aspirin should be:
A. Routinely recommended for all men over 40
B. Considered only if 10-year ASCVD risk ≥10% and no increased
bleeding risk
C. Never used for primary prevention
D. Given only if he has diabetes
: Answer : B
Rationale: The USPSTF recommends low-dose aspirin for primary
prevention in adults 40-59 years with ≥10% 10-year ASCVD risk, after
shared decision-making. It's not routine for all.
8. A mother brings her 4-month-old infant for well-child care. Which
vaccine should the infant receive today?
A. MMR
B. Varicella
pg. 3
