ONCC Practice Tests (OCN -
Oncologic Emergencies 2025-2026)
Questions and Correct Answers
Which of the following cancers is associated with the development of disseminated
intravascular coagulation?
a) Mucin-secreting adenocarcinoma of the breast
b) Nonhyperdiploid variant multiple myeloma
c) Primary peritoneal carcinoma
d) Acral lentiginous melanoma - correct answer a: Mucin-secreting adenocarcinoma of the
breast
Answer: The incidence of disseminated intravascular coagulation is associated mostly with
mucin-secreting adenocarcinomas of the prostate, lung, and breast.
Reference: Kaplan, M. (Ed.). (2013). Understanding and managing oncologic emergencies: A
resource for nurses (2nd ed.). Pittsburgh, PA: Oncology Nursing Society, p. 69.
Which of the following is released into the bloodstream in the event of tumor lysis syndrome?
A. Uric acid
B. Sodium
C. Magnesium
D. Calcium - correct answer A: Uric acid
Answer: Tumor lysis syndrome is a massive, sudden release of cellular contents in to the
bloodstream resulting in elevated uric acid levels.
, Reference: Kaplan, M. (Ed.). (2013). Understanding and managing oncologic emergencies: A
resource for nurses (2nd ed.). Pittsburgh, PA: Oncology Nursing Society, p. 440.
Which of the following classes of medication will most significantly increase the risk for the
development of a cytokine-release syndrome reaction?
A. Monoclonal antibodies
B. Taxanes
C. Platinum compounds
D. Anthracyclines - correct answer A: Monoclonal antibodies
Answer: Monoclonal antibodies can cause cytokine-release syndrome.
Reference: Newton, S., Hickey, M., & Marrs, J. (2017). Mosby's oncology nursing advisor: A
comprehensive guide to clinical practice (2nd ed.). St. Louis, MO: Elsevier Mosby, p. 243.
When a suspected extravasation occurs during the administration of a vesicant, the nurse must
first:
A. stop the administration of medication and fluids.
B. remove the peripheral IV or central venous access device.
C. aspirate the remaining vesicant from the IV tubing.
D. notify the healthcare provider. - correct answer A : stop the administration of medication
and fluids.
Answer: The first step the nurse should take when an extravasation occurs is stopping the
infusion.
Reference: Newton, S., Hickey, M., & Marrs, J. (2017). Mosby's oncology nursing advisor: A
comprehensive guide to clinical practice (2nd ed.). St. Louis, MO: Elsevier Mosby, p. 217.
Oncologic Emergencies 2025-2026)
Questions and Correct Answers
Which of the following cancers is associated with the development of disseminated
intravascular coagulation?
a) Mucin-secreting adenocarcinoma of the breast
b) Nonhyperdiploid variant multiple myeloma
c) Primary peritoneal carcinoma
d) Acral lentiginous melanoma - correct answer a: Mucin-secreting adenocarcinoma of the
breast
Answer: The incidence of disseminated intravascular coagulation is associated mostly with
mucin-secreting adenocarcinomas of the prostate, lung, and breast.
Reference: Kaplan, M. (Ed.). (2013). Understanding and managing oncologic emergencies: A
resource for nurses (2nd ed.). Pittsburgh, PA: Oncology Nursing Society, p. 69.
Which of the following is released into the bloodstream in the event of tumor lysis syndrome?
A. Uric acid
B. Sodium
C. Magnesium
D. Calcium - correct answer A: Uric acid
Answer: Tumor lysis syndrome is a massive, sudden release of cellular contents in to the
bloodstream resulting in elevated uric acid levels.
, Reference: Kaplan, M. (Ed.). (2013). Understanding and managing oncologic emergencies: A
resource for nurses (2nd ed.). Pittsburgh, PA: Oncology Nursing Society, p. 440.
Which of the following classes of medication will most significantly increase the risk for the
development of a cytokine-release syndrome reaction?
A. Monoclonal antibodies
B. Taxanes
C. Platinum compounds
D. Anthracyclines - correct answer A: Monoclonal antibodies
Answer: Monoclonal antibodies can cause cytokine-release syndrome.
Reference: Newton, S., Hickey, M., & Marrs, J. (2017). Mosby's oncology nursing advisor: A
comprehensive guide to clinical practice (2nd ed.). St. Louis, MO: Elsevier Mosby, p. 243.
When a suspected extravasation occurs during the administration of a vesicant, the nurse must
first:
A. stop the administration of medication and fluids.
B. remove the peripheral IV or central venous access device.
C. aspirate the remaining vesicant from the IV tubing.
D. notify the healthcare provider. - correct answer A : stop the administration of medication
and fluids.
Answer: The first step the nurse should take when an extravasation occurs is stopping the
infusion.
Reference: Newton, S., Hickey, M., & Marrs, J. (2017). Mosby's oncology nursing advisor: A
comprehensive guide to clinical practice (2nd ed.). St. Louis, MO: Elsevier Mosby, p. 217.
