What drug class do furosemide and loop diuretics
bumetanide fall under?
what is the pharmacological action of loop - block reabsorption of sodium, chloride, and water in the loop
diuretics? of Henle
Which diuretic class still works well in kidney loop diuretics
impairment?
What are the therapeutic uses associated - reduce edema from HF, cirrhosis, and renal failure
with loop diuretics? - can be used to temporarily treat hypertension from FVE
What are the drug interactions associated - hypokalemia risk: may cause dysrhythmias with digoxin and
with loop diuretics? cardiac glycosides (heart failure meds)
- caution with meds that are nephrotoxic or ototoxic like opioids
and amino-glycoside antibiotics
- may counteract insulin and cause hyperglycemia due to
increased blood concentration
What are the food interactions associated - hawthorn= hypotension
with loop diuretics? - ginseng and high sodium reduce effectiveness
What side effects are associated with loop - hypokalemia and other electrolyte imbalances
diuretics? - dehydration
- hypotension
- hypovolemia
What adverse effects are associated with - ototoxicity: tinitus, vertigo, nausea
loop diuretics? - hyperglycemia
- hyperuricemia
- increased LDL and decreased HDL
What are some nursing interventions for loop - obtain baseline data: vitals, i's&o's, amount and placement of
diuretics? edema, lung sounds, skin turgor, mucus membrane
assessment
- daily weights at same time each day
- monitor electrolyte levels
- monitor BP and HR/pulses before administration
What are some safety considerations for loop tell provider if any of these symptoms develop: dry mouth,
diuretics? increased thirst, muscle cramps, n/v,
symptoms of orthostatic hypotension such as dizziness,
lightheadedness, and syncope may occur
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, 5/22/26, 7:38 PM NUR 354 exam 2 Flashcards | Quizlet
What should you educate patients on if they - change positions slowly
are receiving loop diuretics? - tell provider if signs of dehydration or electrolyte imbalance
occur
How should you evaluate for loop diuretic daily weights, i's&o's, electrolyte levels, kidney function
effectiveness? monitoring (serum creatinine and serum BUN)
What drug class is hydrochlorothiazide in? thiazide diuretic
What is the pharmacological action of blocks sodium, chloride, and water reabsorption in the kidney
thiazide diuretics? tubule which encourages potassium and water excretion
What are the therapeutic uses of thiazide - first choice for treating HTN quickly
diuretics? - edema from HF, liver and kidney disease
- reduces urine production in diabetes insipidus
- good for osteoporosis because it promotes calcium
reabsorption
True or false: thiazide diuretics are equally as false: thiazide diuretics are less effective than loop diuretics
effective as loop diuretics
What are the drug interactions associated - use w/ other HTN meds will add to effects on BP
with thiazide diuretics? - may reduce efficacy of anticoagulants and insulin
- use with NSAIDs increases risk for nephrotoxicity
- hypokalemia= high risk for digoxin toxicity
- carbamazepine and thiazide diuretics increase each-other's
toxicity
What are the food interactions associated - ginko biloba may cause paradoxical interaction and cause
with thiazide diuretics? HTN
- hawthorn may cause hypotension when used with thiazide
diuretics
What are the side effects associated with - hypokalemia and hyponatremia along with other electrolyte
thiazide diuretics? imbalances
- increased risk for gout attacks
- dehydration
What are the adverse effects associated with - pregnancy: decreased placental perfusion
thiazide diuretics? - NOT SAFE FOR USE WITH RENAL IMPAIRMENT
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