NRNP 6531 Final Exam 2025–2026 Actual Questions
and 100% Correct Answers NEW!!!
• 1. Which of the following is a potential acquired cause of thrombophilia?
o Answer: Antiphospholipid antibodies
• 2. Phalen's test (90° wrist flexion for 60 seconds) reproduces symptoms of:
o Answer: Carpal tunnel syndrome
• 3. Which patient would benefit most from screening for type 2 diabetes?
o Answer: An obese female with recurrent vaginitis
• 4. A 72-year-old female patient reports a 6-month history of gradually progressive swollen and painful
distal interphalangeal (DIP) joints of one hand. She has no systemic symptoms, but the erythrocyte
sedimentation rate (ESR), anti-nuclear antibody (ANA), and rheumatoid factor (RF) are all minimally
elevated. What is the most likely diagnosis?
o Answer: Osteoarthritis
• 5. A 32-year-old male patient complains of urinary frequency and burning on urination for 3 days.
Urinalysis reveals bacteriuria. He denies any past history of urinary tract infection. The initial treatment
should be:
o Answer: Trimethoprim-sulfamethoxazole for 3 days
• 6. A thymectomy is usually recommended in the early treatment of which disease?
o Answer: Myasthenia Gravis
• 7. The diagnosis of human papillomavirus (HPV) infection in males is usually made by:
o Answer: Clinical appearance (examination of the lesion)
• 8. The most effective intervention(s) to prevent stroke is/are:
o Answer: Smoking cessation and treatment of hypertension
• 9. What is the most common cause of Cushing's syndrome?
o Answer: Administration of a glucocorticoid or ACTH
• 10. Which of the following medications may predispose the patient to hypoglycemia?
o Answer: Beta-adrenergic blockers
• 11. Diagnostic radiological studies are indicated for low back pain:
o Answer: When there is a suspicion of a space-occupying lesion, fracture, cauda equina, or infection.
• 12. After treating a patient for Helicobacter pylori infection, what test do you order to see if it has been
cured?
o Answer: Urea breath test
• 13. Which appropriate test for the initial assessment of Alzheimer's disease provides performance ratings
on 10 complex, higher-order activities?
o Answer: FAQ (Functional Activities Questionnaire)
• 14. Major depression occurs most often in which of the following conditions?
o Answer: Stroke
• 15. Which of the following statements about multiple sclerosis (MS) is correct?
o Answer: MS is a chronic, treatable illness with an unknown cause and a variable course.
• 16. Diagnostic evaluation of hypothyroidism reveals:
o Answer: Elevated TSH and decreased $T_4$
• 17. Risk factors for prostate cancer include all of the following except:
o Answer: Benign prostatic hypertrophy (BPH)
• 18. What information should patients with diabetes and their families receive about hypoglycemia?
o Answer: Hypoglycemia is serious, dangerous, and can be fatal if not treated quickly.
1/7
, • 19. Which history is commonly found in a patient with glomerulonephritis?
o Answer: Beta-hemolytic streptococcal infection (URI or skin infection)
• 20. Which of the following is characteristic of a manic episode?
o Answer: Grandiose delusions (with a 1-week period of expansive, elevated, or irritable mood)
• 21. Central obesity, "moon" face, and a dorsocervical fat pad are associated with:
o Answer: Cushing's syndrome
• 22. Which of the following is the most common cause of low back pain?
o Answer: Lumbar disc disease
• 23. A middle-aged female presents complaining of recent weight loss. The physical exam reveals an
enlarged, painless cervical lymph node. The differential diagnosis includes:
o Answer: Infection (among other etiologies like malignancy)
• 24. An 81-year-old female is diagnosed with type 2 diabetes. When considering drug therapy for this
patient, the nurse practitioner is most concerned with which side effect?
o Answer: Hypoglycemia
• 25. A patient has an HIV infection and is having problems with massive diarrhea. You suspect the cause
is:
o Answer: Cryptosporidiosis
Questions 26 – 50
• 26. Which of the following is the most common causative organism of non-gonococcal urethritis?
o Answer: Chlamydia trachomatis
• 27. The most common symptoms of a transient ischemic attack (TIA) include:
o Answer: Lower limb weakness, slurred speech, partial vision loss, gait changes
• 28. Diagnostic evaluation for urinary calculi includes: (A) Urinalysis and culture, (B) Non-contrast CT, (C)
Serum calcium, (D) All of the above.
o Answer: D. All of the above
• 29. What is the first symptom seen in the majority of patients with Parkinson's disease?
o Answer: Resting tremor
• 30. A 21-year-old female presents to the office complaining of urinary frequency and burning. The nurse
practitioner suspects a urinary tract infection when the urinalysis reveals:
o Answer: >10 white blood cells per high-powered field
• 31. A 26-year-old female presents with elbow pain described as aching and burning. There is point
tenderness along the lateral aspect of the elbow and painful passive flexion and extension. She reports
playing tennis almost daily. Diagnosis:
o Answer: Lateral epicondylitis
• 32. Maria, age 17, was raped when she was 13 years old. She is now experiencing sleeping problems,
flashbacks, and depression. Initial diagnosis:
o Answer: PTSD
• 33. An elderly man is started on lisinopril and hydrochlorothiazide. Three days later, he presents with an
edematous, erythematous, tender left great toe. The likely precipitant of this pain is:
o Answer: Hydrochlorothiazide (inducing gout)
• 34. Which of the following is a contraindication for metformin therapy?
o Answer: Creatinine > 1.5 mg/dL (or severely impaired renal function)
• 35. A positive drawer sign supports a diagnosis of:
o Answer: Cruciate ligament injury
• 36. Steve, age 69, has GERD. When teaching him how to reduce lower esophageal sphincter pressure,
which substances do you recommend he avoid?
o Answer: Peppermint
• 37. The nurse practitioner diagnoses epididymitis in a 24-year-old sexually active male. The drug of choice
is:
o Answer: Oral doxycycline plus IM ceftriaxone
• 38. Diagnostic confirmation of acute leukemia is based on:
2/7
and 100% Correct Answers NEW!!!
• 1. Which of the following is a potential acquired cause of thrombophilia?
o Answer: Antiphospholipid antibodies
• 2. Phalen's test (90° wrist flexion for 60 seconds) reproduces symptoms of:
o Answer: Carpal tunnel syndrome
• 3. Which patient would benefit most from screening for type 2 diabetes?
o Answer: An obese female with recurrent vaginitis
• 4. A 72-year-old female patient reports a 6-month history of gradually progressive swollen and painful
distal interphalangeal (DIP) joints of one hand. She has no systemic symptoms, but the erythrocyte
sedimentation rate (ESR), anti-nuclear antibody (ANA), and rheumatoid factor (RF) are all minimally
elevated. What is the most likely diagnosis?
o Answer: Osteoarthritis
• 5. A 32-year-old male patient complains of urinary frequency and burning on urination for 3 days.
Urinalysis reveals bacteriuria. He denies any past history of urinary tract infection. The initial treatment
should be:
o Answer: Trimethoprim-sulfamethoxazole for 3 days
• 6. A thymectomy is usually recommended in the early treatment of which disease?
o Answer: Myasthenia Gravis
• 7. The diagnosis of human papillomavirus (HPV) infection in males is usually made by:
o Answer: Clinical appearance (examination of the lesion)
• 8. The most effective intervention(s) to prevent stroke is/are:
o Answer: Smoking cessation and treatment of hypertension
• 9. What is the most common cause of Cushing's syndrome?
o Answer: Administration of a glucocorticoid or ACTH
• 10. Which of the following medications may predispose the patient to hypoglycemia?
o Answer: Beta-adrenergic blockers
• 11. Diagnostic radiological studies are indicated for low back pain:
o Answer: When there is a suspicion of a space-occupying lesion, fracture, cauda equina, or infection.
• 12. After treating a patient for Helicobacter pylori infection, what test do you order to see if it has been
cured?
o Answer: Urea breath test
• 13. Which appropriate test for the initial assessment of Alzheimer's disease provides performance ratings
on 10 complex, higher-order activities?
o Answer: FAQ (Functional Activities Questionnaire)
• 14. Major depression occurs most often in which of the following conditions?
o Answer: Stroke
• 15. Which of the following statements about multiple sclerosis (MS) is correct?
o Answer: MS is a chronic, treatable illness with an unknown cause and a variable course.
• 16. Diagnostic evaluation of hypothyroidism reveals:
o Answer: Elevated TSH and decreased $T_4$
• 17. Risk factors for prostate cancer include all of the following except:
o Answer: Benign prostatic hypertrophy (BPH)
• 18. What information should patients with diabetes and their families receive about hypoglycemia?
o Answer: Hypoglycemia is serious, dangerous, and can be fatal if not treated quickly.
1/7
, • 19. Which history is commonly found in a patient with glomerulonephritis?
o Answer: Beta-hemolytic streptococcal infection (URI or skin infection)
• 20. Which of the following is characteristic of a manic episode?
o Answer: Grandiose delusions (with a 1-week period of expansive, elevated, or irritable mood)
• 21. Central obesity, "moon" face, and a dorsocervical fat pad are associated with:
o Answer: Cushing's syndrome
• 22. Which of the following is the most common cause of low back pain?
o Answer: Lumbar disc disease
• 23. A middle-aged female presents complaining of recent weight loss. The physical exam reveals an
enlarged, painless cervical lymph node. The differential diagnosis includes:
o Answer: Infection (among other etiologies like malignancy)
• 24. An 81-year-old female is diagnosed with type 2 diabetes. When considering drug therapy for this
patient, the nurse practitioner is most concerned with which side effect?
o Answer: Hypoglycemia
• 25. A patient has an HIV infection and is having problems with massive diarrhea. You suspect the cause
is:
o Answer: Cryptosporidiosis
Questions 26 – 50
• 26. Which of the following is the most common causative organism of non-gonococcal urethritis?
o Answer: Chlamydia trachomatis
• 27. The most common symptoms of a transient ischemic attack (TIA) include:
o Answer: Lower limb weakness, slurred speech, partial vision loss, gait changes
• 28. Diagnostic evaluation for urinary calculi includes: (A) Urinalysis and culture, (B) Non-contrast CT, (C)
Serum calcium, (D) All of the above.
o Answer: D. All of the above
• 29. What is the first symptom seen in the majority of patients with Parkinson's disease?
o Answer: Resting tremor
• 30. A 21-year-old female presents to the office complaining of urinary frequency and burning. The nurse
practitioner suspects a urinary tract infection when the urinalysis reveals:
o Answer: >10 white blood cells per high-powered field
• 31. A 26-year-old female presents with elbow pain described as aching and burning. There is point
tenderness along the lateral aspect of the elbow and painful passive flexion and extension. She reports
playing tennis almost daily. Diagnosis:
o Answer: Lateral epicondylitis
• 32. Maria, age 17, was raped when she was 13 years old. She is now experiencing sleeping problems,
flashbacks, and depression. Initial diagnosis:
o Answer: PTSD
• 33. An elderly man is started on lisinopril and hydrochlorothiazide. Three days later, he presents with an
edematous, erythematous, tender left great toe. The likely precipitant of this pain is:
o Answer: Hydrochlorothiazide (inducing gout)
• 34. Which of the following is a contraindication for metformin therapy?
o Answer: Creatinine > 1.5 mg/dL (or severely impaired renal function)
• 35. A positive drawer sign supports a diagnosis of:
o Answer: Cruciate ligament injury
• 36. Steve, age 69, has GERD. When teaching him how to reduce lower esophageal sphincter pressure,
which substances do you recommend he avoid?
o Answer: Peppermint
• 37. The nurse practitioner diagnoses epididymitis in a 24-year-old sexually active male. The drug of choice
is:
o Answer: Oral doxycycline plus IM ceftriaxone
• 38. Diagnostic confirmation of acute leukemia is based on:
2/7
