D115 COMPREHENSIVE EXAM Advanced
Pathophysiology for the Advanced
Practice Nurse (Latest )
Questions and Verified Answers 100%
Correct (Grade A)- WGU
The primary defect in osteoarthritis is- correct answer The primary defect in
osteoarthritis is Local areas of damage and loss of articular cartilage, new bone
formation of joint margins, and thickening of joint capsule
A person has gout. Which typical clinical manifestation may be found upon
assessment?- correct answer Tophi
Feedback: Clinical manifestations of gout include: Pain in the great toe (usually, but not
always): Worse at night Increase in serum urate concentration: Hyperuricemia
Recurrent attacks of monoarticular arthritis: Inflammation of a single joint Deposits of
monosodium urate monohydrate (tophi) in and around the joints Renal disease,
involving glomerular, tubular, and interstitial tissues and blood vessels Formation of
renal stones
,Allergic contact dermatitis is associated with :- correct answer delayed
hypersensitivity - Allergic contact dermatitis is a common form of T-cell mediated or
delayed hypersensitivity (type IV).
The FNP is seeing an older adult female patient who complains of a tender area on her
torso that extends from her spine around and under her breast to the sternum on the
left side. She states the pain has been present for 2 days, and today she has developed
clusters of "blisters". What is the diagnostic test that the FNP would perform?- correct
answer Polymerase chain reaction (PCR)
Feedback: PCR can be used to detect VZV DNA rapidly and sensitively, and is now
widely available.
In regards to the case above, what would be your suspected diagnosis?- correct
answer Herpes zoster typically presents with a history of tenderness followed by
eruptions and vesicles that follow a dermatome on one side of the body.
, Which risk factor is associated with gout?- correct answer Ingestion of salicylate-
containing medications
Feedback: Gout is associated with use of some medications including salicylates,
diuretics, pyrazinamide, and alcohol.
A child with Down's syndrome has had frequent respiratory tract infections since birth.
What should the APRN tell the parent is the underlying cause of this illness?- correct
answer Gastroesophageal reflux disease causes aspiration of thin fluids.
Feedback: Gastroesophageal reflux is commonly seen in children with Down syndrome
and can be severe enough to result in aspiration of stomach contents, causing
respiratory symptoms such as persistent coughing, wheezing, and pneumonia
The FNP understands that a female patient with a complete or partial absence of the
second sex chromosome may also display which of the following physical signs?-
correct answer Ovarian failure
Feedback: Turner's syndrome occurs in approximately 1 in 2500 live births. It is
diagnosed by complete or partial absence of the second sex chromosome (45, X).
Patients may also demonstrate congenital lymphedema of hands and feet, webbed
Pathophysiology for the Advanced
Practice Nurse (Latest )
Questions and Verified Answers 100%
Correct (Grade A)- WGU
The primary defect in osteoarthritis is- correct answer The primary defect in
osteoarthritis is Local areas of damage and loss of articular cartilage, new bone
formation of joint margins, and thickening of joint capsule
A person has gout. Which typical clinical manifestation may be found upon
assessment?- correct answer Tophi
Feedback: Clinical manifestations of gout include: Pain in the great toe (usually, but not
always): Worse at night Increase in serum urate concentration: Hyperuricemia
Recurrent attacks of monoarticular arthritis: Inflammation of a single joint Deposits of
monosodium urate monohydrate (tophi) in and around the joints Renal disease,
involving glomerular, tubular, and interstitial tissues and blood vessels Formation of
renal stones
,Allergic contact dermatitis is associated with :- correct answer delayed
hypersensitivity - Allergic contact dermatitis is a common form of T-cell mediated or
delayed hypersensitivity (type IV).
The FNP is seeing an older adult female patient who complains of a tender area on her
torso that extends from her spine around and under her breast to the sternum on the
left side. She states the pain has been present for 2 days, and today she has developed
clusters of "blisters". What is the diagnostic test that the FNP would perform?- correct
answer Polymerase chain reaction (PCR)
Feedback: PCR can be used to detect VZV DNA rapidly and sensitively, and is now
widely available.
In regards to the case above, what would be your suspected diagnosis?- correct
answer Herpes zoster typically presents with a history of tenderness followed by
eruptions and vesicles that follow a dermatome on one side of the body.
, Which risk factor is associated with gout?- correct answer Ingestion of salicylate-
containing medications
Feedback: Gout is associated with use of some medications including salicylates,
diuretics, pyrazinamide, and alcohol.
A child with Down's syndrome has had frequent respiratory tract infections since birth.
What should the APRN tell the parent is the underlying cause of this illness?- correct
answer Gastroesophageal reflux disease causes aspiration of thin fluids.
Feedback: Gastroesophageal reflux is commonly seen in children with Down syndrome
and can be severe enough to result in aspiration of stomach contents, causing
respiratory symptoms such as persistent coughing, wheezing, and pneumonia
The FNP understands that a female patient with a complete or partial absence of the
second sex chromosome may also display which of the following physical signs?-
correct answer Ovarian failure
Feedback: Turner's syndrome occurs in approximately 1 in 2500 live births. It is
diagnosed by complete or partial absence of the second sex chromosome (45, X).
Patients may also demonstrate congenital lymphedema of hands and feet, webbed
