1|Page
APEA PATHOPHYSIOLOGY EXAM REVIEW BANK
(MASTER 1 & 2) | {LATEST 2026/ 2027 UPDATE}
COMPLETE ACTUAL AND AUTHENTIC EXAM |
BRAND NEW!
APEA Pathophysiology - MASTER 2
The pediatric orthopedic condition described as osteonecrosis of the
capital femoral epiphysis due to interrupted vascular supply that results
in ischemia and alteration in cartilage growth is:
toxic synovitis.
Legg-Calve-Perthes disease.
spondyloepiphyseal dysplasia.
juvenile rheumatoid arthritis. ......ANSWER......Legg-Calve-Perthes
disease.
A 54-year-old woman reports left wrist stiffness at rest and with
movement. An X-ray of the left wrist identifies joint space narrowing,
bony erosion in the joint, and reduced bone density surrounding the
joint. What is the probable diagnosis?
Bursitis
Osteoarthritis
Systemic lupus
Rheumatoid arthritis ......ANSWER......Rheumatoid arthritis
pg. 1
,2|Page
A lateral deviation of the spinal column that may cause rotation or
deformity in the vertebrae is termed:
scoliosis.
osteoporosis.
Legg Calve Perthes disease.
Osgood Schlatter disease. ......ANSWER......scoliosis.
Synovial fluid does NOT:
reduce the friction between articular cartilage of synovial joints during
movement.
provide nutrition to the avascular articular cartilage.
regenerate bone epiphyses.
aid in shock absorption. ......ANSWER......regenerate bone epiphyses.
The most common site of curvature in a patient with scoliosis is:
the left cervical spine.
the right lumbar spine.
the left lumbar spine.
the right thoracic spine. ......ANSWER......the right thoracic spine.
The pathologic hallmark of juvenile rheumatoid arthritis is:
inflamed synovial tissue.
pg. 2
,3|Page
osteophyte development.
subchondral sclerosis.
popliteal cyst rupture. ......ANSWER......inflamed synovial tissue.
The skeletal disorder characterized by loss of total bone mass and
increased bone fragility is termed:
rickets.
osteomalacia.
osteopenia.
osteoporosis. ......ANSWER......osteoporosis.
A 50-year-old woman reports morning joint stiffness that lasts less than
1 hour and resumes after activity. During physical examination, the NP
detects crepitus. This symptom indicates:
rheumatoid arthritis.
bursitis.
tendonitis.
osteoarthritis. ......ANSWER......osteoarthritis.
Which one of the following diseases is associated with neuromuscular
scoliosis?
Fibromyalgia
Spinal stenosis
pg. 3
, 4|Page
Cerebral palsy
Multiple sclerosis ......ANSWER......Cerebral palsy
Osteomalacia is caused by a deficiency in:
iron.
vitamin D.
phosphate.
vitamin C. ......ANSWER......vitamin D
A pathologic alteration in the musculotendinous origins of the extensor
carpi radialis brevis muscle and longus tendons as a result of overuse is:
lateral epicondylitis.
synovitis of the elbow.
cubital tunnel syndrome.
bursitis. ......ANSWER......lateral epicondylitis.
The major clinical manifestation of rheumatoid arthritis is:
joint swelling.
deep tendon hyporeflexia.
decreased range of motion.
ecchymosis in the affected site. ......ANSWER......joint swelling
pg. 4
APEA PATHOPHYSIOLOGY EXAM REVIEW BANK
(MASTER 1 & 2) | {LATEST 2026/ 2027 UPDATE}
COMPLETE ACTUAL AND AUTHENTIC EXAM |
BRAND NEW!
APEA Pathophysiology - MASTER 2
The pediatric orthopedic condition described as osteonecrosis of the
capital femoral epiphysis due to interrupted vascular supply that results
in ischemia and alteration in cartilage growth is:
toxic synovitis.
Legg-Calve-Perthes disease.
spondyloepiphyseal dysplasia.
juvenile rheumatoid arthritis. ......ANSWER......Legg-Calve-Perthes
disease.
A 54-year-old woman reports left wrist stiffness at rest and with
movement. An X-ray of the left wrist identifies joint space narrowing,
bony erosion in the joint, and reduced bone density surrounding the
joint. What is the probable diagnosis?
Bursitis
Osteoarthritis
Systemic lupus
Rheumatoid arthritis ......ANSWER......Rheumatoid arthritis
pg. 1
,2|Page
A lateral deviation of the spinal column that may cause rotation or
deformity in the vertebrae is termed:
scoliosis.
osteoporosis.
Legg Calve Perthes disease.
Osgood Schlatter disease. ......ANSWER......scoliosis.
Synovial fluid does NOT:
reduce the friction between articular cartilage of synovial joints during
movement.
provide nutrition to the avascular articular cartilage.
regenerate bone epiphyses.
aid in shock absorption. ......ANSWER......regenerate bone epiphyses.
The most common site of curvature in a patient with scoliosis is:
the left cervical spine.
the right lumbar spine.
the left lumbar spine.
the right thoracic spine. ......ANSWER......the right thoracic spine.
The pathologic hallmark of juvenile rheumatoid arthritis is:
inflamed synovial tissue.
pg. 2
,3|Page
osteophyte development.
subchondral sclerosis.
popliteal cyst rupture. ......ANSWER......inflamed synovial tissue.
The skeletal disorder characterized by loss of total bone mass and
increased bone fragility is termed:
rickets.
osteomalacia.
osteopenia.
osteoporosis. ......ANSWER......osteoporosis.
A 50-year-old woman reports morning joint stiffness that lasts less than
1 hour and resumes after activity. During physical examination, the NP
detects crepitus. This symptom indicates:
rheumatoid arthritis.
bursitis.
tendonitis.
osteoarthritis. ......ANSWER......osteoarthritis.
Which one of the following diseases is associated with neuromuscular
scoliosis?
Fibromyalgia
Spinal stenosis
pg. 3
, 4|Page
Cerebral palsy
Multiple sclerosis ......ANSWER......Cerebral palsy
Osteomalacia is caused by a deficiency in:
iron.
vitamin D.
phosphate.
vitamin C. ......ANSWER......vitamin D
A pathologic alteration in the musculotendinous origins of the extensor
carpi radialis brevis muscle and longus tendons as a result of overuse is:
lateral epicondylitis.
synovitis of the elbow.
cubital tunnel syndrome.
bursitis. ......ANSWER......lateral epicondylitis.
The major clinical manifestation of rheumatoid arthritis is:
joint swelling.
deep tendon hyporeflexia.
decreased range of motion.
ecchymosis in the affected site. ......ANSWER......joint swelling
pg. 4
