MSN 672 MODULE 3 QUIZ QUESTIONS
COMPLETE SOLUTIONS FINAL STUDY
GUIDE REVIEW SET 2026 GRADED A+
⩥ Highest EPS risk antipsychotic class.
Answer: High-potency first-generation antipsychotics (FGAs) Haldol &
Prolixin (fluphenazine). It is reversible.
⩥ Lowest EPS risk antipsychotics.
Answer: Clozapine and quetiapine (fast D2 dissociation).
⩥ Cause of tardive dyskinesia.
Answer: Chronic D2 blockade → dopamine supersensitivity.
⩥ Treatment for tardive dyskinesia.
Answer: It is irreversible. VMAT2 inhibitors (valbenazine,
deutetrabenazine), amantadine, switch to clozapine.
⩥ Black Box Warning for antipsychotics.
Answer: ↑ Mortality in elderly patients with dementia-related psychosis.
⩥ Features of Neuroleptic Malignant Syndrome (NMS).
, Answer: Rigidity, hyperthermia, AMS, autonomic instability, ↑ CK. It is
life threatening.
⩥ Treatment of NMS.
Answer: Stop drug, ICU care, dantrolene, bromocriptine.
⩥ Key metabolic labs before starting antipsychotics.
Answer: CBC, CMP, A1C, lipids, weight/BMI, vitals, ECG.
⩥ SGAs with most metabolic risk.
Answer: Olanzapine, clozapine.
⩥ Antipsychotics causing most prolactin elevation.
Answer: Risperidone and paliperidone.
⩥ TCAs lethal in overdose.
Answer: Cardiac sodium channel blockade → fatal arrhythmias.
⩥ SSRI mechanism of action.
Answer: Block SERT, ↑ serotonin in cleft.
⩥ Why SSRIs take weeks to work.
COMPLETE SOLUTIONS FINAL STUDY
GUIDE REVIEW SET 2026 GRADED A+
⩥ Highest EPS risk antipsychotic class.
Answer: High-potency first-generation antipsychotics (FGAs) Haldol &
Prolixin (fluphenazine). It is reversible.
⩥ Lowest EPS risk antipsychotics.
Answer: Clozapine and quetiapine (fast D2 dissociation).
⩥ Cause of tardive dyskinesia.
Answer: Chronic D2 blockade → dopamine supersensitivity.
⩥ Treatment for tardive dyskinesia.
Answer: It is irreversible. VMAT2 inhibitors (valbenazine,
deutetrabenazine), amantadine, switch to clozapine.
⩥ Black Box Warning for antipsychotics.
Answer: ↑ Mortality in elderly patients with dementia-related psychosis.
⩥ Features of Neuroleptic Malignant Syndrome (NMS).
, Answer: Rigidity, hyperthermia, AMS, autonomic instability, ↑ CK. It is
life threatening.
⩥ Treatment of NMS.
Answer: Stop drug, ICU care, dantrolene, bromocriptine.
⩥ Key metabolic labs before starting antipsychotics.
Answer: CBC, CMP, A1C, lipids, weight/BMI, vitals, ECG.
⩥ SGAs with most metabolic risk.
Answer: Olanzapine, clozapine.
⩥ Antipsychotics causing most prolactin elevation.
Answer: Risperidone and paliperidone.
⩥ TCAs lethal in overdose.
Answer: Cardiac sodium channel blockade → fatal arrhythmias.
⩥ SSRI mechanism of action.
Answer: Block SERT, ↑ serotonin in cleft.
⩥ Why SSRIs take weeks to work.