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HESI A2 Cardiovascular System Study Guide 2026 | Anatomy & Physiology Practice Questions and Answers

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Strengthen your understanding of the Cardiovascular System for the HESI A2 Anatomy and Physiology section with this focused study guide designed for nursing school applicants. This resource includes detailed review notes, practice questions with answer explanations, and essential concepts covering heart anatomy, blood circulation, cardiac physiology, arteries, veins, blood flow, and major cardiovascular functions commonly tested on the HESI A2 exam. Ideal for nursing entrance exam preparation, this guide helps students improve comprehension, retain key anatomy concepts, and boost confidence for exam success.

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Hesi A2
Course
Hesi A2

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HESI A2 Cardiovascular
System Study Guide 2026 |
Anatomy & Physiology
Practice Questions and
Answers
|Graded A+ | Guaranteed
success|




Updated 2026 Questions and Answers
100% Verified Exam Prep and Comprehensive
Rationales
Included

, What vessel carries oxygenated blood? Pulmonary Vein


What valve prevents the backflow of blood from the right right atrioventricular valve (tricuspid valve)
ventricle into the right atrium?


Autorhythmicity is the responsibility of Cardiac pacemaker cells


The right and left atria depolarize and contract following SA node
the arrival of the action potential from the


High pressured blood in the ventricles force what to Semilunar valves
open?


How much blood is pumped from each ventricle during 70 mL
the ventricular ejection phase?


Which hormone decreases cardiac output by decreasing atrial natriuretic peptide
blood volume and preload?


What is the function of the valves in the heart? prevent backflow of blood through the heart


What vessel(s) deliver oxygenated blood to the left pulmonary veins
atrium?


During what part of the action potential will calcium ions Plateau Phase
enter the contractile cell?


The P wave on an electrocardiogram (ECG) represents Atria
the depolarization of cells in the:


What decreases heart rate? Acetylcholine


Walls of the heart Epicardium=Outer Layer
Myocardium=Middle Layer
Endocardium= Inner Layer


Pulmonary Blood Circuit Right ventricle to Lungs to Left Ventricle


Systemic Blood Circuit Left Ventricle to Body to Right Atrium


Full Blood Flow Vena Cava to Right Atrium to Right Ventricle to Pulmonary Artery to Lungs to
Pulmonary Veins to Left Atrium to Left Ventricle to Aorta to Body


Blood Supply to the Heart Left Coronary Artery supplies blood to left heart wall
Right Coronary Artery supplies blood to right heart wall


Heart conduction system SA Node to AV Node to Bundle of Heart to Bundle Branches to Purkinje Fibers

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