pass 2025/2026
Amitriptyline (RX) brand - correct answer ✔Elavil,
Amitriptyline (RX) indications - correct answer ✔1. Depression
Amitriptyline (RX) dosage forms - correct answer ✔Oral Tablet: 10 mg, 25 mg, 50 mg, 75 mg, 100 mg,
150 mg
Amitriptyline (RX) dosing - correct answer ✔1. Depression: 25-50 mg po daily divided into 1-2 daily
doses, titrate to max 300 mg/d
Amitriptyline (RX) MoA - correct answer ✔-tricyclic antidepressant that blocks presynaptic reuptake of
serotonin and norepinephrine with subsequent downregulation of adrenergic receptor
Amitriptyline (RX) renal adjustment? - correct answer ✔no
Amitriptyline (RX) contraindications - correct answer ✔-Hypersensitivity
-concurrent MAOI or MAOI use in last 14 d
-use during acute recovery period after MI
-coadministration of cisapride
Amitriptyline (RX) adr - correct answer ✔C:Sedation
LC:Blurred vision, confusion, constipation, dizziness, sexual dysfunction, somnolence, urinary retention,
weight gain, xerostomia
RBS:Cardiac dysrhythmia, hepatotoxicity, seizures, suicidal thoughts
, Amitriptyline (RX) kcp - correct answer ✔-Avoid activities requiring mental alertness, alcohol, and other
CNS depressants.
-Symptomatic improvement may not be seen for a few weeks.
-Avoid sudden discontinuation of drug.
Amitriptyline (RX) bbw - correct answer ✔Suicidality in young adults, adolescents, and children
Gabapentin (RX) brand - correct answer ✔Neurontin, Gralise
Gabapentin (RX) indications - correct answer ✔1. Partial seizure, adjunct
2. Postherpetic neuralgia
Gabapentin (RX) dosage forms - correct answer ✔-Oral Capsule: 100 mg, 300 mg, 400 mg
-Oral Tablet: 600 mg, 800 mg
-Oral Solution: 250 mg/5 mL
-Oral Tablet, Extended Release: 300 mg, 600 mg
Gabapentin (RX) dosing - correct answer ✔1. Partial seizure, adjunct: Immediate release
initial, 300 mg po tid, may titrate to 1800 mg/d in 3 divided doses (max 2400-3600 mg/d)
2. Postherpetic neuralgia: Immediate release,300 mg po on day 1, 300 mg bid on day 2, 300 mg tid on
day 3, may titrate dose to 1800-3600 mg/d in 3 divided doses; ER, 300 mg on day 1, 600 mg on day 2,
900 mg days 3-6, 1200 mg days 7-10, 1500 mg days 11-14, and 1800 mg po daily thereafter
Gabapentin (RX) MoA - correct answer ✔-cyclohexane compound that is structurally related to GABA;
its mechanism of action is not known.