Page 1 of 62
AANP FNP CERTIFICATION EXAM AND
STUDY GUIDE 2026- 250+ QUESTIONS AND
ANSWERS (VERIFIED ANSWERS)
AANP EXAM QUESTIONS LATEST UPDATE
1. A 65-year-old woman presents for a follow-up examination after a new patient
visit. She has not seen a healthcare provider for several years. She is a
smoker and her hypertension is now adequately controlled with medication.
Her mother died at age 40 from a heart attack. The fasting lipid profile shows
cholesterol = 240 mg/dL, HDL = 30, and LDL = 200. In addition to starting
Therapeutic Lifestyle Changes, the nurse practitioner should start the patient
on:
1. bile acid sequestrant.
2. a statin drug.
3. a cholesterol absorption inhibitor.
4. low-dose aspirin. - ANSWER-A statin drug
2. The most commonly prescribed medication for mild systemic lupus
erythematosus (SLE) is:
1
,Page 2 of 62
1. azathioprine (AZA).
2. belimumab (Benlysta).
3. ibuprofen (Advil).
4. cyclophosphamide (Cytoxan). - ANSWER-ibuprofen (advil)
The most common sign of cervical cancer is:
1. postcoital bleeding.
2. strong odor from vaginal discharge.
3. itching in the vaginal area.
4. molluscum contagiosum. - ANSWER-postcoital bleeding
The nurse practitioner prescribes amitriptyline (Elavil) for a patient with
neuropathic pain secondary to diabetes mellitus. On follow-up, the patient
complains of urine retention and dry mouth. The practitioner would:
1. discontinue amitriptyline and begin ibuprofen (Motrin).
2. refer to physical therapy.
3. start methocarbamol (Robaxin).
4. discontinue amitriptyline and begin gabapentin (Neurontin). - ANSWER-
discontinue amitriptyline and begin gabapentin (neurontin)
2
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A 17-year-old male with rheumatoid arthritis is being treated with an NSAID and
omeprazole (Prilosec). The patient complains of headache, abdominal pain, and
gas. These symptoms are most likely:
1. associated with the omeprazole.
2. related to the underlying condition.
3. the result of the NSAID.
4. caused by viral gastroenteritis. - ANSWER-associated with the omeprazole
The medication of choice for the initial treatment of juvenile rheumatoid arthritis
is:
1. acetaminophen.
2. prednisone.
3. aspirin.
4. ibuprofen. - ANSWER-ibuprofen
A 12-year-old with sickle cell anemia has recently experienced a sickle cell crisis
and presents for a follow-up examination after a recent hospitalization. It is most
important to continue monitoring growth, development, and:
1. white blood cell levels.
2. fecal occult blood test.
3. hemoglobin levels.
3
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4. urine dipsticks. - ANSWER-hemoglobin levels
A 90-year-old female is brought to the clinic by her neighbor. She states that
everything is fine, but the nurse practitioner notes that she has poor hygiene and
bruises on her trunk. The neighbor is concerned that the patient often has no
money to buy food, despite income from social security and a coal miner's
pension. The nurse practitioner suspects abuse. Which of the following is the
nurse practitioner obligated to do next?
1. Report the case to the proper authorities.
2. Tell the neighbor to check on the woman daily and report back.
3. Document the data and report the information to risk management.
4. Call the patient's family and inquire about the concerns. - ANSWER-report the
case to proper authorities
In most cases, the first manifestation of Alzheimer's disease is:
1. impaired judgment.
2. decrease in short-term memory.
3. disorientation in time and place.
4. decrease in long-term memory. - ANSWER-decrease in short-term memory
The optimal treatment for latent tuberculosis is:
1. rifampin (Rifadin) for 5 months.
2. isoniazid (Nydrazid) for 9 months.
4
AANP FNP CERTIFICATION EXAM AND
STUDY GUIDE 2026- 250+ QUESTIONS AND
ANSWERS (VERIFIED ANSWERS)
AANP EXAM QUESTIONS LATEST UPDATE
1. A 65-year-old woman presents for a follow-up examination after a new patient
visit. She has not seen a healthcare provider for several years. She is a
smoker and her hypertension is now adequately controlled with medication.
Her mother died at age 40 from a heart attack. The fasting lipid profile shows
cholesterol = 240 mg/dL, HDL = 30, and LDL = 200. In addition to starting
Therapeutic Lifestyle Changes, the nurse practitioner should start the patient
on:
1. bile acid sequestrant.
2. a statin drug.
3. a cholesterol absorption inhibitor.
4. low-dose aspirin. - ANSWER-A statin drug
2. The most commonly prescribed medication for mild systemic lupus
erythematosus (SLE) is:
1
,Page 2 of 62
1. azathioprine (AZA).
2. belimumab (Benlysta).
3. ibuprofen (Advil).
4. cyclophosphamide (Cytoxan). - ANSWER-ibuprofen (advil)
The most common sign of cervical cancer is:
1. postcoital bleeding.
2. strong odor from vaginal discharge.
3. itching in the vaginal area.
4. molluscum contagiosum. - ANSWER-postcoital bleeding
The nurse practitioner prescribes amitriptyline (Elavil) for a patient with
neuropathic pain secondary to diabetes mellitus. On follow-up, the patient
complains of urine retention and dry mouth. The practitioner would:
1. discontinue amitriptyline and begin ibuprofen (Motrin).
2. refer to physical therapy.
3. start methocarbamol (Robaxin).
4. discontinue amitriptyline and begin gabapentin (Neurontin). - ANSWER-
discontinue amitriptyline and begin gabapentin (neurontin)
2
,Page 3 of 62
A 17-year-old male with rheumatoid arthritis is being treated with an NSAID and
omeprazole (Prilosec). The patient complains of headache, abdominal pain, and
gas. These symptoms are most likely:
1. associated with the omeprazole.
2. related to the underlying condition.
3. the result of the NSAID.
4. caused by viral gastroenteritis. - ANSWER-associated with the omeprazole
The medication of choice for the initial treatment of juvenile rheumatoid arthritis
is:
1. acetaminophen.
2. prednisone.
3. aspirin.
4. ibuprofen. - ANSWER-ibuprofen
A 12-year-old with sickle cell anemia has recently experienced a sickle cell crisis
and presents for a follow-up examination after a recent hospitalization. It is most
important to continue monitoring growth, development, and:
1. white blood cell levels.
2. fecal occult blood test.
3. hemoglobin levels.
3
, Page 4 of 62
4. urine dipsticks. - ANSWER-hemoglobin levels
A 90-year-old female is brought to the clinic by her neighbor. She states that
everything is fine, but the nurse practitioner notes that she has poor hygiene and
bruises on her trunk. The neighbor is concerned that the patient often has no
money to buy food, despite income from social security and a coal miner's
pension. The nurse practitioner suspects abuse. Which of the following is the
nurse practitioner obligated to do next?
1. Report the case to the proper authorities.
2. Tell the neighbor to check on the woman daily and report back.
3. Document the data and report the information to risk management.
4. Call the patient's family and inquire about the concerns. - ANSWER-report the
case to proper authorities
In most cases, the first manifestation of Alzheimer's disease is:
1. impaired judgment.
2. decrease in short-term memory.
3. disorientation in time and place.
4. decrease in long-term memory. - ANSWER-decrease in short-term memory
The optimal treatment for latent tuberculosis is:
1. rifampin (Rifadin) for 5 months.
2. isoniazid (Nydrazid) for 9 months.
4
