Questions and Answers 2026 Update
know very well which drugs cause weight gain and
hypoglycemia - Correct Answers ✅Both: Sulfonyreas, basal
insulin
Weight gain only: Thiazolidinediones (TZD),
DM drug that cause GI disturbances - Correct Answers
✅Metformin
Root ending with class of med:
Sulfonylureas
Thiazolidinediones
GLP-1 Agonists
DPP4 Inhibitors
SGLT-2 inhibitors - Correct Answers ✅Sulfonylureas = "-
ides"
Thiazolidinediones = "-zones"
GLP-1 Agonists = "-tides"
DPP4 Inhibitors = "-liptins"
SGLT-2 inhibitors = "-flozins"
MOA for insulin (understand it, don't just memorize),
absorption and duration factors - Correct Answers ✅signals
liver to convert glucose to glycogen (storage) and prevents
glycogen breakdown when BG high
, Advanced pharm exam 3- Diabetes
Questions and Answers 2026 Update
•Absorption factors: type/concentration, blood flow to area,
injection site (abdomen pref)
•Peak duration factors: injection site, duration of DM, renal
function, smoking status, etc.
insulin needs to be renaly dosed in kidney dysfunction -
Correct Answers ✅
insulin disadvantages - Correct Answers ✅*Weight Gain
*HYPOglycemia
rapid-acting insulins - Correct Answers ✅Novolog (insulin
aspart), Humalog (insulin lispro)
-dosed with meals
-onset 10-20 minutes
short-acting insulin - Correct Answers ✅Regular (Humulin
R, Novolin R) -dosed with meals -onset 30-60 min
concept of U-100 insulin vs U-500 - Correct Answers ✅U-
100 less concentrated, U-500 nost concentrated (lower
volume for higher impact)
Intemediate acting insulin - Correct Answers ✅NPH 70/30
-twice daily dosing