Questions & Answers New Update
1. Rotigotine - >>>>>> Neupro patch: do not heat/ use during MRI
2. HLA b1502 - >>>>>> Test in Asians. Rash for carbamazepine (tegretol), phenytoin (Dilantin), fos
phenytoin (cerebyx)
3. Trastuzumab - >>>>>> Herceptin, her/Neu- ado-trastuzunab (kadcyla), lapatinib (tykerb) pertuzumab
(perjeta)
4. Hla- b 5701 - >>>>>> Don't give abacavir (ziagen), epzicom, trizivir
5. Not cross reactive a/ opioid allergy - >>>>>> Fentanyl, meperidine (Demerol), methadone
(dolophine), tramadol (ultram), tapentadol (nucynta)
6. Inducers - >>>>>> Ps porcs (phenytoin, smoking, phenobarbital, oxcarbazepine, rifampin,
carbamazepine, St. John's wort)
7. Inhibitors - >>>>>> Gpacman (grapefruit, pi's, azoles, cimetidine/cyclosporine, macrolides-
erytho/clarithro, amiodarone, non dihydro (dilt, verapamil))
8. If on amiodarone, decrease these drugs by 30-50% - >>>>>> Digoxin, warfarin, quinidine,
procainanide, statins
9. Statins with high risk of inhibition - >>>>>> Las (lova, atorva, simva)
10. Entecavir - >>>>>> Baraclude. Empty stomach for hep B that fail lamivudime and adefovir- se:
peripheral edema, nephrotoxic
,11. Ribavirin - >>>>>> Copegus. W/ food bid for hep c, hepatotoxic, hemolytic anemia, preg x, psych
disorders, ci: renal disfxn
12. Glipizide - >>>>>> Glucotrol 30 min before break & dinner
13. Glimeprimide - >>>>>> Amaryl 1-2 mg qd w/ 1st meal
14. Glyburide - >>>>>> Diabeta, + metformin = glucovance, do not use w/ renal failure 2.5-5mg qd
15. Rosiglitazone - >>>>>> Avandia 4-8mg qd (tzd, exacerbate hf, liver damage, increases hdl, decreases
tg/total cholesterol) similar: pioglitazone (actos)
16. Repaglinide - >>>>>> Prandin 0.5-2mg TID 15-30 min before a meal, hypoglycemia- do not take with
su's
17. Nateglinide - >>>>>> Starlix injection- 15-30 min before meals
18. Acarbose - >>>>>> Precose- w/ 1st bite of meal and water
19. Miglitol - >>>>>> Glyset w/ 1st bite of meal and water
20. Linagliptan - >>>>>> Tradjenta- 5 mg qd in morning with or without food, no renal adjustment
21. Saxagliptin - >>>>>> OnglyZa 2.5-5mg qd
22. Canaglifozin - >>>>>> Invokana 100mg qd before first meal of day for DM. Se: female genital mycotic
infxn, increased urination, hyperkalemia, can increase dig levels, ci: renal dx
, 23. Exenatide - >>>>>> Byetta 30-60 min before am & pm meals, medguide, pancreatitis, thyroid c-cell
carcinoma xr= bydureon
24. Liraglutide - >>>>>> Victoza QD thyroid c-cell carcinoma, more weight loss, less pancreatitis
25. Pramlintide - >>>>>> Symlin - injection, skip if no meals, weight loss
26. Insulin aspart - >>>>>> Novolog rapid
27. Insulin glulisine - >>>>>> Apidra rapid
28. Insulin lispro - >>>>>> Humalog rapid
29. Detemir - >>>>>> Levemir long acting
30. Insulin glargine - >>>>>> Lantus long acting
31. Ibandronate - >>>>>> Boniva 150 monthly
32. Zolendrenic acid - >>>>>> Reclast iv - pretreat w/nsaids
33. Teriparatide - >>>>>> Forteo SC daily: osteosarcoma, kidney stones, orthostatic hypotension,
hypocalcemia- must take ca starting 2 weeks before time- fridge after each dose, sit while giving
34. Lotensin - >>>>>> Benazepril
35. Indapamide - >>>>>> Lozol 1.25-5mg- thiazide diuretic
36. Aerobid - >>>>>> Budesonide inhaler