CSL Donor Floor Questions & Answers | Plasma
Center Training Exam Study Guide | Donor Floor
Technician Certification Prep 2026
• This study guide contains 200 practice questions designed to prepare you for the
CSL Plasma Donor Floor Technician Certification Exam — read each question
carefully, review the EXPERT RATIONALE for every correct answer, and revisit any
topic where you feel uncertain.
• Features include bolded questions and correct answers, A–E multiple choice
format, clear EXPERT RATIONALE, and full topic coverage including donor
screening, venipuncture, adverse reactions, equipment, compliance, and safety
protocols.
QUESTION 1: What is the maximum whole blood volume that can be collected
from a donor weighing less than 175 lbs during a plasmapheresis procedure?
A) 690 mL
B) 750 mL
C) 800 mL
D) 690 mL based on donor weight calculation
E) 500 mL
Correct Answer: D) 690 mL based on donor weight calculation
EXPERT RATIONALE: CSL Behring protocol requires that the extracorporeal volume
and total blood draw be calculated based on donor body weight. Donors under 175
lbs have a lower allowable draw volume to protect donor safety.
QUESTION 2: What is the minimum acceptable total protein level for a donor
to be eligible to donate plasma?
A) 5.0 g/dL
B) 5.5 g/dL
C) 5.8 g/dL
,D) 6.0 g/dL
E) 6.5 g/dL
Correct Answer: D) 6.0 g/dL
EXPERT RATIONALE: CSL requires a minimum total protein of 6.0 g/dL to ensure
the donor has adequate protein levels to safely donate plasma without risk of
protein depletion.
QUESTION 3: How often must a donor's total protein be tested at a CSL
plasma center?
A) Every donation
B) Once a year
C) Every 6 months
D) Every 4 months
E) Every 2 months
Correct Answer: D) Every 4 months
EXPERT RATIONALE: Per CSL SOP, total protein must be checked at least every four
months to monitor ongoing donor health and eligibility for continued plasma
donation.
QUESTION 4: What is the minimum hematocrit level required for a female
donor to be eligible to donate?
A) 34%
B) 35%
C) 36%
D) 38%
E) 40%
, Correct Answer: D) 38%
EXPERT RATIONALE: CSL Behring requires female donors to have a minimum
hematocrit of 38% to ensure they are not anemic and can safely undergo
plasmapheresis without adverse effects.
QUESTION 5: What is the minimum hematocrit level required for a male donor
to donate plasma?
A) 36%
B) 37%
C) 38%
D) 39%
E) 40%
Correct Answer: D) 39%
EXPERT RATIONALE: Male donors must have a minimum hematocrit of 39% per
CSL protocol. This higher threshold compared to females accounts for physiological
differences in red blood cell volume.
QUESTION 6: What should a Donor Floor Technician do FIRST when a donor
reports feeling dizzy during donation?
A) Stop the machine and call a nurse
B) Elevate the donor's legs immediately
C) Offer the donor juice or snacks
D) Clamp the line, notify the nurse, and stay with the donor
E) Complete the donation and then assess
Correct Answer: D) Clamp the line, notify the nurse, and stay with the donor
, EXPERT RATIONALE: Donor safety is the top priority. Clamping the line stops
further blood loss, notifying the nurse ensures medical oversight, and staying with
the donor prevents injury if they lose consciousness.
QUESTION 7: Which of the following is a contraindication for plasma donation
at CSL?
A) Seasonal allergies
B) Use of antacids
C) Pregnancy
D) History of mild asthma well-controlled
E) Use of vitamins
Correct Answer: C) Pregnancy
EXPERT RATIONALE: Pregnant women are permanently deferred from donating
plasma at CSL centers. Pregnancy poses significant risk to both the mother and
fetus due to volume shifts and protein loss.
QUESTION 8: What angle should the needle be inserted at during
venipuncture for plasmapheresis?
A) 5–10 degrees
B) 20–30 degrees
C) 15–35 degrees
D) 45 degrees
E) 10–15 degrees
Correct Answer: C) 15–35 degrees
Center Training Exam Study Guide | Donor Floor
Technician Certification Prep 2026
• This study guide contains 200 practice questions designed to prepare you for the
CSL Plasma Donor Floor Technician Certification Exam — read each question
carefully, review the EXPERT RATIONALE for every correct answer, and revisit any
topic where you feel uncertain.
• Features include bolded questions and correct answers, A–E multiple choice
format, clear EXPERT RATIONALE, and full topic coverage including donor
screening, venipuncture, adverse reactions, equipment, compliance, and safety
protocols.
QUESTION 1: What is the maximum whole blood volume that can be collected
from a donor weighing less than 175 lbs during a plasmapheresis procedure?
A) 690 mL
B) 750 mL
C) 800 mL
D) 690 mL based on donor weight calculation
E) 500 mL
Correct Answer: D) 690 mL based on donor weight calculation
EXPERT RATIONALE: CSL Behring protocol requires that the extracorporeal volume
and total blood draw be calculated based on donor body weight. Donors under 175
lbs have a lower allowable draw volume to protect donor safety.
QUESTION 2: What is the minimum acceptable total protein level for a donor
to be eligible to donate plasma?
A) 5.0 g/dL
B) 5.5 g/dL
C) 5.8 g/dL
,D) 6.0 g/dL
E) 6.5 g/dL
Correct Answer: D) 6.0 g/dL
EXPERT RATIONALE: CSL requires a minimum total protein of 6.0 g/dL to ensure
the donor has adequate protein levels to safely donate plasma without risk of
protein depletion.
QUESTION 3: How often must a donor's total protein be tested at a CSL
plasma center?
A) Every donation
B) Once a year
C) Every 6 months
D) Every 4 months
E) Every 2 months
Correct Answer: D) Every 4 months
EXPERT RATIONALE: Per CSL SOP, total protein must be checked at least every four
months to monitor ongoing donor health and eligibility for continued plasma
donation.
QUESTION 4: What is the minimum hematocrit level required for a female
donor to be eligible to donate?
A) 34%
B) 35%
C) 36%
D) 38%
E) 40%
, Correct Answer: D) 38%
EXPERT RATIONALE: CSL Behring requires female donors to have a minimum
hematocrit of 38% to ensure they are not anemic and can safely undergo
plasmapheresis without adverse effects.
QUESTION 5: What is the minimum hematocrit level required for a male donor
to donate plasma?
A) 36%
B) 37%
C) 38%
D) 39%
E) 40%
Correct Answer: D) 39%
EXPERT RATIONALE: Male donors must have a minimum hematocrit of 39% per
CSL protocol. This higher threshold compared to females accounts for physiological
differences in red blood cell volume.
QUESTION 6: What should a Donor Floor Technician do FIRST when a donor
reports feeling dizzy during donation?
A) Stop the machine and call a nurse
B) Elevate the donor's legs immediately
C) Offer the donor juice or snacks
D) Clamp the line, notify the nurse, and stay with the donor
E) Complete the donation and then assess
Correct Answer: D) Clamp the line, notify the nurse, and stay with the donor
, EXPERT RATIONALE: Donor safety is the top priority. Clamping the line stops
further blood loss, notifying the nurse ensures medical oversight, and staying with
the donor prevents injury if they lose consciousness.
QUESTION 7: Which of the following is a contraindication for plasma donation
at CSL?
A) Seasonal allergies
B) Use of antacids
C) Pregnancy
D) History of mild asthma well-controlled
E) Use of vitamins
Correct Answer: C) Pregnancy
EXPERT RATIONALE: Pregnant women are permanently deferred from donating
plasma at CSL centers. Pregnancy poses significant risk to both the mother and
fetus due to volume shifts and protein loss.
QUESTION 8: What angle should the needle be inserted at during
venipuncture for plasmapheresis?
A) 5–10 degrees
B) 20–30 degrees
C) 15–35 degrees
D) 45 degrees
E) 10–15 degrees
Correct Answer: C) 15–35 degrees
