ADVANCED PHARMACOLOGY FOR
PRESCRIBERS STUDY SHEET 2026 EXAM
QUESTIONS AND ANSWERS EXPERT
VERIFIED
◉Isotretinoin - Monitor. Answer: Prescribed only by dermatologists.
Baseline CBC, both baseline, and monthly liver function tests
throughout the treatment, baseline, and monthly pregnancy test
throughout the treatment serum lipid profile.
An ophthalmological examination is required if visual difficulties
occur, with a second examination 6 to 7 weeks after discontinuation
of the medication.
◉Isotretinoin - ADR. Answer: Cheilitis (inflammation of the lips)
occur in 90% of pts. Dry skin, pruritus, skin fragility in 80%
Conjunctivitis in 40%
,Drying of mucous membranes in 30%
Visual disturbances 25%
Hypertriglyceridemia in 45%
Elevation of glucose and exacerbation of DM, Increased HGB/HCT,
ESR, HA, lethargy, fatigue, pseudotumor cerebri
Depression (d/c tx if occurs)
Hepatitis (d/c tx if occurs)
◉Benzoyl peroxide - type of drug. Answer: topical ATB
◉Benzoyl Peroxide - MOA. Answer: Produces free oxygen radicals
that oxidizes P. acnes protein
Comedolytic and anti-inflammatory
◉Benzoyl peroxide - Indication. Answer: topical agent for acne
vulgaris
,◉Benzoyl peroxide - ADR. Answer: Localized skin irritation
Increased risk for secondary infection
Tolerance with prolonged use (reversible)
Pts w/ liver failure or children more at risk for systemic absorption
◉Clobetasol - type of drug. Answer: topical corticosteroid - high
potency
◉Clobetasol - MOA. Answer: Anti-inflammatory that inhibits the
formation, release, and activity of endogenous mediators of
inflammation (kinins, histamine, liposomal enzymes,
prostaglandins).
Inhibit the migration of macrophages and leukocytes into area by
reversing vascular dilation and permeability.
Antimitotic effect on epidermal cells
Pregnancy Cat C
, ◉Clobetasol - Indication. Answer: Inflammatory skin diseases
Psoriasis
CI: monotherapy for bacterial infections, rosacea, acne vulgaris. High
potency CI in groin, face, axilla application and children.
◉Clobetasol - Monitor. Answer: Adrenal function in children for high
potency or occlusion being used
Adrenal function in adults using >50g/week of high potency
Growth in children using mid-high potency
◉Clobetasol - ADR. Answer: Localized skin irritation
Increased risk for secondary infection
Tolerance with prolonged use (reversible)
Pts w/ liver failure or children more at risk for systemic absorption
PRESCRIBERS STUDY SHEET 2026 EXAM
QUESTIONS AND ANSWERS EXPERT
VERIFIED
◉Isotretinoin - Monitor. Answer: Prescribed only by dermatologists.
Baseline CBC, both baseline, and monthly liver function tests
throughout the treatment, baseline, and monthly pregnancy test
throughout the treatment serum lipid profile.
An ophthalmological examination is required if visual difficulties
occur, with a second examination 6 to 7 weeks after discontinuation
of the medication.
◉Isotretinoin - ADR. Answer: Cheilitis (inflammation of the lips)
occur in 90% of pts. Dry skin, pruritus, skin fragility in 80%
Conjunctivitis in 40%
,Drying of mucous membranes in 30%
Visual disturbances 25%
Hypertriglyceridemia in 45%
Elevation of glucose and exacerbation of DM, Increased HGB/HCT,
ESR, HA, lethargy, fatigue, pseudotumor cerebri
Depression (d/c tx if occurs)
Hepatitis (d/c tx if occurs)
◉Benzoyl peroxide - type of drug. Answer: topical ATB
◉Benzoyl Peroxide - MOA. Answer: Produces free oxygen radicals
that oxidizes P. acnes protein
Comedolytic and anti-inflammatory
◉Benzoyl peroxide - Indication. Answer: topical agent for acne
vulgaris
,◉Benzoyl peroxide - ADR. Answer: Localized skin irritation
Increased risk for secondary infection
Tolerance with prolonged use (reversible)
Pts w/ liver failure or children more at risk for systemic absorption
◉Clobetasol - type of drug. Answer: topical corticosteroid - high
potency
◉Clobetasol - MOA. Answer: Anti-inflammatory that inhibits the
formation, release, and activity of endogenous mediators of
inflammation (kinins, histamine, liposomal enzymes,
prostaglandins).
Inhibit the migration of macrophages and leukocytes into area by
reversing vascular dilation and permeability.
Antimitotic effect on epidermal cells
Pregnancy Cat C
, ◉Clobetasol - Indication. Answer: Inflammatory skin diseases
Psoriasis
CI: monotherapy for bacterial infections, rosacea, acne vulgaris. High
potency CI in groin, face, axilla application and children.
◉Clobetasol - Monitor. Answer: Adrenal function in children for high
potency or occlusion being used
Adrenal function in adults using >50g/week of high potency
Growth in children using mid-high potency
◉Clobetasol - ADR. Answer: Localized skin irritation
Increased risk for secondary infection
Tolerance with prolonged use (reversible)
Pts w/ liver failure or children more at risk for systemic absorption
