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Dermatologie Samenvatting | Klinisch eindexamen | UA | 2025/26

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Samenvatting Dermatologie Klinisch eindexamen Geneeskunde Universiteit Antwerpen. De samenvatting behandelt de 13 hoofdstukken van de U-ask me lijst: psoriasis, pityriasis rosea, eczeem, bacteriële/virale/mycologische infecties, urticaria, medicamenteuze erupties, vaatpathologie, dermatologische oncologie, acné, haar- en nagelpathologie, vasculitis, pigmentstoornissen en bulleuze aandoeningen.

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U ASK ME
DERMATOLOGIE




KLINISCH EINDEXAMEN
2025-2026

,INHOUDSTAFEL
1. Psoriasis............................................................................................................................................................... 2
2. Pityriasis rosea van Gilbert .................................................................................................................................. 5
3. Eczeem ................................................................................................................................................................ 6
4. Bacteriële, virale en mycologische infecties ..................................................................................................... 11
5. Urticaria, prurigo en pruritus ............................................................................................................................ 27
6. Medicamenteuze erupties, purpura, erythema exsudativum multifome ......................................................... 31
7. Vaatpathologie - Ulcera .................................................................................................................................... 37
8. Dermatologische oncologie............................................................................................................................... 40
9. Acné .................................................................................................................................................................. 46
10. Haar- en nagelpathologie ................................................................................................................................ 49
11. Vasculitis, auto-immune en interne aandoeningen ........................................................................................ 53
12. Pigmentstoornissen......................................................................................................................................... 67
13. Bulleuze aandoeningen ................................................................................................................................... 70
14. Belangrijke aanvullingen ................................................................................................................................. 72




1

,1. PSORIASIS
DEFINITIE

- Chronisch
- Niet infectieus
- Inflammatoir
- NIET besmettelijk

ETHIOPATHOGENESE

 Genetische inflammatoire epidermale celproliferatie (continue renovatie bovenste huidlaag)

UITLOKKENDE FACTOREN

- Infectie
o Streptococcus pyogenes voor psoriasis guttata (= druppelvorm)
- Medicatie (!)
o Betablokkers
o Antimalariamedicatie (Plaquenil)
o Lithium
- Stress (fysiek en mentaal)

KLINIEK

- Plaque psoriasis
o = scherp afgelijnde, rode plaques met dikke witte schilfering
 eczeem: niet goed afgelijnd
- Symmetrisch (!)
o Knieën en ellebogen (strekzijde) ( eczeem in plooien!)
o Lage rug
o Schedelhuid
 Symmetrisch = oorzaak van binnenuit (bv. medicatie)  assymetrisch = oorzaak van buitenaf

ANDERE KLINISCHE VORMEN

- Guttata vorm (afb LB)
o = druppelvorm
- Inversa
o In lichaamsplooien
o 3 plaatsen: bilspleet , liezen, navel
▪ DD: candida in liesplooi
- Palmoplantair
o Beperkt tot handen en voeten (afb RB)
- Pustuleus (LO en RO)
- Psoriasis erythrodermie
o Rood van kop tot teen (afb)
▪ Kan ook door eczeem




2

, - Nagelaantasting
o Onycholyse
▪ = loslating van nagelplaat van nagelbed → witte kleur
▪ Kan ook door candida, te smalle schoenen
o Pitting = vingerhoedsnagel
▪ Enkel bij psoriasis te zien !!
o Olievlekfenomeen
▪ Bruin/geel verkleuring van de nagel
o Subunguale hyperkeratose




BEHANDELING

FASE 1: LOKAAL

- Keratolytica
o Vermindert schilfering
- Topische corticoïden
o Anti-inflammatoir
o Zalf > crème
- Vitamine D analogen
o Anti-schilfering
o Calcipotriol (enkel nog in combinatieproducten)
▪ Betamethason
+ calpotriol = dovobet®
o Tacalcitol




 Mogen in gezicht
o Hydrocortisone acetaat
o Clobetazone butyraat
o Triamcinolone acetonide
o Mometasone fuoraat
o Hydrocortisone butyraat




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