WBI11 01 Biology Unit 1: Molecules, Diet, Transport and Health exam

Molecules, Transport and Health - Questions by Topic


Ql.

Many studies have linked the development of atherosclerosis with cardiovascular disease (CVD).

(a) The photograph shows a section through an artery with a plaque (atheroma) from a patient
with atherosclerosis.




*(c) Cholesterol is transported in the blood as lipoproteins LDL and HDL.

In one study, the relationship between total blood cholesterol and the risk of death from CVD
was investigated.
plaque
The results are shown in the graph.



Key

··o.. Northern- urope
--+-- United States
-sv- Southern-Europe,
inland
•••·· Southern-Europe,
Q Ogphoto/i5t.ock mediterranean


Calculate the percentage increase in the thickness of the artery wall where the plaque is located.

Take your measurements along the line labelled X-Y. 3.5 4 4.5 5 5.5 6 6.5 7.5 8 8.5
Total cholesterol/mmoldm-1
(3)
Graph 1
Answer .................................................................... %
In another study, the effect of the size of LDL and the ratio of total blood cholesterol to HDL on
(b) Explain how atherosclerosis can result in damage to the heart muscle. the relative risk of CVD was investigated.

(4) The results are shown in the graph.




Edexce/ (/AL) Biology A-level PhysicsAndMathsTutor.com Edexce/ (/AL) Biology A-level 2 PhysicsAndMathsTutor.com

, Ratio of total blood
cholesterol to HDL
4 Key
0 ,_
c; -
<6
0 3 (Total for question = 13 marks)
."
'1! ,_ -
0>6
· -
O i -
a:
-


0
·- - ,_ -




Small Large
Size of LDLmolecule

Graph 2

Assess the contribution of lipoproteins to the risk of developing CVD. Use the information in the
graph to support your answer.

(6)




Edexce/ (/AL) Biology A-level 3 PhysicsAndMathsTutor.com Edexce/ (/AL) Biology A-level 4 PhysicsAndMathsTutor.com