NSG 318 EXAM 3 INTRODUCTION TO
PHARMACOLOGY EXAM QUESTIONS AND
CORRECT ANSWERS (VERIFIED ANSWERS) Q&A
2026 |INSTANT DOWNLOAD PDF
1. Which term describes the movement of a drug from its site
of administration into the bloodstream?
A. Distribution
B. Metabolism
C. Absorption
D. Excretion
Answer: C. Absorption
Rationale: Absorption is the process by which a drug enters
systemic circulation.
2. What is the primary organ responsible for drug
metabolism?
A. Kidney
B. Liver
C. Heart
D. Lungs
Answer: B. Liver
Rationale: The liver contains enzymes that chemically alter
drugs.
,3. Which route of administration avoids first-pass
metabolism?
A. Oral
B. Sublingual
C. Rectal
D. Enteral
Answer: B. Sublingual
Rationale: Sublingual drugs enter directly into circulation,
bypassing the liver initially.
4. The therapeutic index of a drug refers to:
A. Drug absorption rate
B. Drug safety margin
C. Drug half-life
D. Drug potency
Answer: B. Drug safety margin
Rationale: It compares effective dose to toxic dose.
5. What is a drug’s half-life?
A. Time to peak effect
B. Time to eliminate all drug
C. Time for half the drug to be eliminated
D. Time to onset
,Answer: C. Time for half the drug to be eliminated
Rationale: Half-life determines dosing frequency.
6. Pharmacodynamics refers to:
A. Drug movement in the body
B. Drug effects on the body
C. Drug metabolism
D. Drug excretion
Answer: B. Drug effects on the body
Rationale: It studies how drugs produce effects.
7. A drug that produces the same effect as a natural substance
is a:
A. Antagonist
B. Agonist
C. Partial agonist
D. Inhibitor
Answer: B. Agonist
Rationale: Agonists activate receptors.
8. A drug that blocks receptor activity is called:
A. Agonist
B. Antagonist
C. Enzyme
, D. Catalyst
Answer: B. Antagonist
Rationale: Antagonists prevent receptor activation.
9. Which factor affects drug absorption?
A. Blood flow
B. pH
C. Surface area
D. All of the above
Answer: D. All of the above
Rationale: All influence drug absorption rate.
10. Bioavailability refers to:
A. Drug metabolism
B. Drug concentration in tissues
C. Amount of drug reaching circulation
D. Drug excretion rate
Answer: C. Amount of drug reaching circulation
Rationale: It measures drug availability in blood.
11. Distribution of drugs is influenced by:
A. Protein binding
B. Blood flow
C. Tissue permeability
PHARMACOLOGY EXAM QUESTIONS AND
CORRECT ANSWERS (VERIFIED ANSWERS) Q&A
2026 |INSTANT DOWNLOAD PDF
1. Which term describes the movement of a drug from its site
of administration into the bloodstream?
A. Distribution
B. Metabolism
C. Absorption
D. Excretion
Answer: C. Absorption
Rationale: Absorption is the process by which a drug enters
systemic circulation.
2. What is the primary organ responsible for drug
metabolism?
A. Kidney
B. Liver
C. Heart
D. Lungs
Answer: B. Liver
Rationale: The liver contains enzymes that chemically alter
drugs.
,3. Which route of administration avoids first-pass
metabolism?
A. Oral
B. Sublingual
C. Rectal
D. Enteral
Answer: B. Sublingual
Rationale: Sublingual drugs enter directly into circulation,
bypassing the liver initially.
4. The therapeutic index of a drug refers to:
A. Drug absorption rate
B. Drug safety margin
C. Drug half-life
D. Drug potency
Answer: B. Drug safety margin
Rationale: It compares effective dose to toxic dose.
5. What is a drug’s half-life?
A. Time to peak effect
B. Time to eliminate all drug
C. Time for half the drug to be eliminated
D. Time to onset
,Answer: C. Time for half the drug to be eliminated
Rationale: Half-life determines dosing frequency.
6. Pharmacodynamics refers to:
A. Drug movement in the body
B. Drug effects on the body
C. Drug metabolism
D. Drug excretion
Answer: B. Drug effects on the body
Rationale: It studies how drugs produce effects.
7. A drug that produces the same effect as a natural substance
is a:
A. Antagonist
B. Agonist
C. Partial agonist
D. Inhibitor
Answer: B. Agonist
Rationale: Agonists activate receptors.
8. A drug that blocks receptor activity is called:
A. Agonist
B. Antagonist
C. Enzyme
, D. Catalyst
Answer: B. Antagonist
Rationale: Antagonists prevent receptor activation.
9. Which factor affects drug absorption?
A. Blood flow
B. pH
C. Surface area
D. All of the above
Answer: D. All of the above
Rationale: All influence drug absorption rate.
10. Bioavailability refers to:
A. Drug metabolism
B. Drug concentration in tissues
C. Amount of drug reaching circulation
D. Drug excretion rate
Answer: C. Amount of drug reaching circulation
Rationale: It measures drug availability in blood.
11. Distribution of drugs is influenced by:
A. Protein binding
B. Blood flow
C. Tissue permeability
