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CHEM 280 Midterm Exam 2026 | 200 Practice Questions with Answers & Explanations | Latest Update

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CHEM 280 Midterm Exam 2026 | 200 Practice Questions with Answers & Explanations | Latest Update

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Chem 280 Midterm – General Chemistry (Allied Health /
Nursing) Complete 200-Practice-Question Bank with Verified
Answers & Explanations

BLOCK 1: MATTER, MEASUREMENT, AND UNITS (Questions 1–30)



Q1. Chemistry is the study of:

A) Living organisms only

B) Matter and its transformations

C) Mathematical principles

D) The Earth’s geological composition



Answer: B

Explanation: Chemistry studies the composition, structure, properties, and changes of matter – the
material that makes up the universe.



Q2. Which of the following is an example of a qualitative observation?

A) The water temperature is 25°C.

B) The solution turned blue.

C) The mass is 10.5 g.

D) The volume is 50.0 mL.



Answer: B

Explanation: Qualitative observations describe properties without numbers (color, odor, state).
Quantitative observations involve measurements with numbers and units.



Q3. The SI base unit of length is the:

A) Centimeter

B) Meter

,C) Kilometer

D) Inch



Answer: B

Explanation: The meter (m) is the SI base unit of length. Other units are derived or metric but not base
SI.



Q4. The SI base unit of mass is the:

A) Gram

B) Pound

C) Kilogram

D) Ounce



Answer: C

Explanation: The kilogram (kg) is the SI base unit of mass. The gram is a derived unit (1 kg = 1000 g).



Q5. The SI base unit of time is the:

A) Minute

B) Hour

C) Second

D) Day



Answer: C

Explanation: The second (s) is the SI base unit of time.



Q6. Which prefix represents \(10^{-3}\)?

A) Milli

B) Centi

C) Micro

,D) Kilo



Answer: A

Explanation: milli‑ = \(10^{-3}\) (0.001). Centi = \(10^{-2}\), micro = \(10^{-6}\), kilo = \(10^{3}\).



Q7. How many significant figures are in 0.003040?

A) 7

B) 5

C) 4

D) 3



Answer: C

Explanation: Leading zeros are not significant. The digits “3040” – the zero after 4 is significant because
it’s after a non‑zero digit and decimal is present. So 4 significant figures.



Q8. Convert 1.25 L to mL.

A) 0.00125 mL

B) 125 mL

C) 1250 mL

D) 12.5 mL



Answer: C

Explanation: 1 L = 1000 mL; 1.25 × 1000 = 1250 mL.



Q9. Convert 25°C to Kelvin.

A) 298 K

B) 248 K

C) 273 K

D) 300 K

, Answer: A

Explanation: K = °C + 273.15 ≈ 25 + 273 = 298 K.



Q10. A graduated cylinder contains 50.0 mL of water. A rock added raises the level to 65.2 mL. The
rock’s volume is:

A) 15.2 mL

B) 50.0 mL

C) 65.2 mL

D) 115.2 mL



Answer: A

Explanation: Volume of rock = final volume – initial volume = 65.2 – 50.0 = 15.2 mL.



Q11. Density is defined as:

A) Mass × Volume

B) Volume / Mass

C) Mass / Volume

D) Mass + Volume



Answer: C

Explanation: Density = mass / volume (g/mL or g/cm³).



Q12. What is the density of a substance with mass 25.0 g and volume 5.0 mL?

A) 0.20 g/mL

B) 5.0 g/mL

C) 125 g/mL

D) 2.0 g/mL

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