PMHNP 2 ACTUAL EXAM QUESTIONS
AND COMPLETE STUDY GUIDE 2026
▶ A male patient informs an adult psychiatric and mental health nurse practitioner that
he has not slept in three days, has poor concentration, and denies fatigue. The patient's
diagnosis is:
A. attention-deficit hyperactivity disorder.
B. bipolar disorder.
C. panic disorder.
D. primary insomnia. Answer: B. bipolar disorder.
▶ During patient education about sertraline (Zoloft), an adult psychiatric and mental
health nurse practitioner focuses upon the potential side effect of:
A. agranulocytosis.
B. hypernatremia.
C. sexual dysfunction.
D. weight loss. Answer: C. sexual dysfunction
▶ The neurochemical pathophysiology of Tourette disorder involves:
A. decreased levels of gamma-aminobutyric acid and increased levels of glutamate in
the brain.
B. deficits in the prefrontal cortex-mediated executive functions of the brain.
C. imbalances in dopaminergic, serotonergic, and noradrenergic systems in multiple
regions of the brain.
D. overstimulation of noradrenergic activity located in the locus coeruleus of the brain.
Answer: C. imbalances in dopaminergic, serotonergic, and noradrenergic systems in
multiple regions of the brain.
▶ Before implementing evidence-based practice changes, an adult psychiatric and
mental health nurse practitioner's initial action is to:
A. brainstorm with stakeholders and draft a detailed problem list.
B. compare data with internal and external benchmarks, and coordinate ongoing
education.
C. facilitate a collaborative multidisciplinary group to synthesize evidence and compare
key themes.
D. identify potential barriers and facilitators that reflect patients' values and
expectations. Answer: D. identify potential barriers and facilitators that reflect patients'
values and expectations.
▶ 17. Symptoms of anxiety and panic are associated with a low level of which
neurotransmitter?
A. Cortisol
AND COMPLETE STUDY GUIDE 2026
▶ A male patient informs an adult psychiatric and mental health nurse practitioner that
he has not slept in three days, has poor concentration, and denies fatigue. The patient's
diagnosis is:
A. attention-deficit hyperactivity disorder.
B. bipolar disorder.
C. panic disorder.
D. primary insomnia. Answer: B. bipolar disorder.
▶ During patient education about sertraline (Zoloft), an adult psychiatric and mental
health nurse practitioner focuses upon the potential side effect of:
A. agranulocytosis.
B. hypernatremia.
C. sexual dysfunction.
D. weight loss. Answer: C. sexual dysfunction
▶ The neurochemical pathophysiology of Tourette disorder involves:
A. decreased levels of gamma-aminobutyric acid and increased levels of glutamate in
the brain.
B. deficits in the prefrontal cortex-mediated executive functions of the brain.
C. imbalances in dopaminergic, serotonergic, and noradrenergic systems in multiple
regions of the brain.
D. overstimulation of noradrenergic activity located in the locus coeruleus of the brain.
Answer: C. imbalances in dopaminergic, serotonergic, and noradrenergic systems in
multiple regions of the brain.
▶ Before implementing evidence-based practice changes, an adult psychiatric and
mental health nurse practitioner's initial action is to:
A. brainstorm with stakeholders and draft a detailed problem list.
B. compare data with internal and external benchmarks, and coordinate ongoing
education.
C. facilitate a collaborative multidisciplinary group to synthesize evidence and compare
key themes.
D. identify potential barriers and facilitators that reflect patients' values and
expectations. Answer: D. identify potential barriers and facilitators that reflect patients'
values and expectations.
▶ 17. Symptoms of anxiety and panic are associated with a low level of which
neurotransmitter?
A. Cortisol
