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HCR 240 PATHOPHYSIOLOGY | EXAM 3 | QUESTIONS & ANSWERS | 2026 LATEST UPDATED| GET A+

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HCR 240 PATHOPHYSIOLOGY | EXAM 3 | QUESTIONS & ANSWERS | 2026 LATEST UPDATED| GET A+

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HCR 240 PATHOPHYSIOLOGY | EXAM 3 | QUESTIONS & ANSWERS |

2026 LATEST UPDATED| GET A+

Triad of Virchow - (answer)Venous stasis

Venous endothelial damage

Hypercoagulable states




What are the 3 factors that are critically important in the development of venous thrombosis

called? - (answer)Triad of Virchow




orthostatic hypotension - (answer)Low blood pressure that occurs upon standing up




Isolated systolic hypertension - (answer)Elevated systolic blood pressure accompanied by normal

diastolic blood pressure




primary hypertension - (answer)High blood pressure, the cause of which is unknown but thought

to maybe be genetic or environmental; also known as essential hypertension




Secondary hypertension - (answer)Is caused by systemic disease that raises peripheral vascular

resistance and/or cardiac output

,Systolic hypertension - (answer)Most significant factor in causing target organ damage




Non-modifiable risk factors of hypertension - (answer)Age, gender, family history




Modifiable risk factors of hypertension - (answer)-↑Sodium (Na+) intake

-Glucose intolerance (diabetes -mellitus)/insulin resistance

-Heavy alcohol use

-Obesity

-Cigarettes

-↓Potassium (K+), magnesium (Mg++), calcium (Ca++)




Hypertension - (answer)Caused by increases in cardiac output or total peripheral resistance, or

both




Any condition that increases heart rate or stroke volume? - (answer)Cardiac output




Effects of primary hypertension - (answer)-Overactivity of the sympathetic nervous system and

renin-angiotensin-aldosterone system (RAAS), and alterations in natriuretic peptides

,-Inflammation, endothelial dysfunction, obesity-related hormones, and insulin resistance




Complicated hypertension - (answer)Hypertrophy and hyperplasia with associated fibrosis of the

tunica intima and media in a process called vascular remodeling




Malignant hypertension (hypertensive crisis) - (answer)-Rapidly progressive hypertension

-Diastolic pressure is usually >140 mmHg

-Can lead to encephalopathy




Clinical manifestations of hypertension - (answer)-Early stages of hypertension have no clinical

manifestations other than elevated blood pressure.

-Called the silent disease




Treatment of hypertension - (answer)-Reducing or eliminating risk factors

-Dietary approaches to stop hypertension (DASH)

-Cessation of smoking

-Exercise program that promotes endurance and relaxation

, Orthosatic hypotension - (answer)Decrease in the systolic and diastolic blood pressures on

standing by 20 mmHg or more and by 10 mmHg or more, respectively




Clinical manifestations of orthostatic hypotension - (answer)Fainting upon standing

Treatment




Treatment of orthostatic hypotension - (answer)Liberalize salt intake, raise the head of the bed,

wear thigh-high stockings, expand volume with mineralocorticoids, and administer

vasoconstrictors




Primary orthostatic hypotension - (answer)-called neurogenic (results from neurologic disorders

affecting autonomic function)

-often chronic

-seen in older adults (Parkinson disease)




Secondary orthostatic hypotension - (answer)acute and associated with:

-altered body chemistry

-drug action (antihypertensive or antidepressants)

-prolonged immobility caused by illness

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