MMSC 423 HEMATOLOGY FINAL EXAM
SCRIPT 2026 COMPREHENSIVE QUESTIONS
AND ANSWERS VERIFIED A+
●● What is the buffy coat? Answer: A component of blood that contains
leukocytes and platelets, accounting for less than 1% of total blood.
●● What is hemostasis? Answer: The arrest of bleeding by spontaneous
formation of a hemostatic platelet plug.
●● What are the major elements of plasma? Answer: Water, proteins,
antibodies, lipids, carbohydrates, electrolytes, clotting factors, enzymes,
vitamins, and hormones.
●● Serum Answer: obtained from coagulated blood and lacks fibrinogen
●● Plasma Answer: obtained from anticoagulated blood and contains
fibrinogen.
●● What is vasoconstriction? Answer: The narrowing of blood vessels
caused by muscular walls tightening, reducing blood flow and increasing
blood pressure.
, ●● What is thrombocytopenia? Answer: An abnormally low platelet
count leading to poor blood clotting and increased bleeding risk.
●● What is thrombocytosis? Answer: An abnormally high platelet count.
●● What are procoagulants? Answer: Substances that promote
coagulation, including vWF, TAFI, P-selectin, PAI-1, tissue factor, and
collagen.
●● What are anticoagulants? Answer: Substances that inhibit
coagulation, such as heparin sulfate, TPA, ECPR, TFPI,
thrombinmodulin, nitrous oxide, and PGI2.
●● How are platelets produced? Answer: Platelets are shed from
megakaryocytes in the bone marrow.
●● What is the lifespan of platelets? Answer: 7-10 days.
●● What is a normal platelet count? Answer: 150,000-450,000 uL.
●● What is the peripheral zone of a platelet? Answer: The stimulus
receptor/transmitter region including the glycocalyx, platelet membrane,
open canalicular zone, and submembrane region.
SCRIPT 2026 COMPREHENSIVE QUESTIONS
AND ANSWERS VERIFIED A+
●● What is the buffy coat? Answer: A component of blood that contains
leukocytes and platelets, accounting for less than 1% of total blood.
●● What is hemostasis? Answer: The arrest of bleeding by spontaneous
formation of a hemostatic platelet plug.
●● What are the major elements of plasma? Answer: Water, proteins,
antibodies, lipids, carbohydrates, electrolytes, clotting factors, enzymes,
vitamins, and hormones.
●● Serum Answer: obtained from coagulated blood and lacks fibrinogen
●● Plasma Answer: obtained from anticoagulated blood and contains
fibrinogen.
●● What is vasoconstriction? Answer: The narrowing of blood vessels
caused by muscular walls tightening, reducing blood flow and increasing
blood pressure.
, ●● What is thrombocytopenia? Answer: An abnormally low platelet
count leading to poor blood clotting and increased bleeding risk.
●● What is thrombocytosis? Answer: An abnormally high platelet count.
●● What are procoagulants? Answer: Substances that promote
coagulation, including vWF, TAFI, P-selectin, PAI-1, tissue factor, and
collagen.
●● What are anticoagulants? Answer: Substances that inhibit
coagulation, such as heparin sulfate, TPA, ECPR, TFPI,
thrombinmodulin, nitrous oxide, and PGI2.
●● How are platelets produced? Answer: Platelets are shed from
megakaryocytes in the bone marrow.
●● What is the lifespan of platelets? Answer: 7-10 days.
●● What is a normal platelet count? Answer: 150,000-450,000 uL.
●● What is the peripheral zone of a platelet? Answer: The stimulus
receptor/transmitter region including the glycocalyx, platelet membrane,
open canalicular zone, and submembrane region.
