The Immune System 5th Edition
by Peter Parham
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, Table of content
1. Elements of the Immune System and Their Roles in Defense
2. Innate Immunity: The Immediate Response to Infection
3. Innate Immunity: The Induced Response to Infection
4. Antibody Structure and the Generation of B-Cell Diversity
5. Antigen Recognition by T Lymphocytes
6. The Development of B Lymphocytes
7. The Development of T Lymphocytes
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8. T Cell-Mediated Immunity
9. Immunity Mediated by B Cells and Antibodies
10. Preventing Infection at Mucosal Surfaces
11. Immunological Memory and Vaccination
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12. Natural Killer Cells
13. Unconventional Lymphoid Cells
14. Failures of the Body’s Defenses
15. Allergy and the Immune Response to Parasites
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16. Transplantation of Tissues and Organs
17. Disruption of Healthy Tissue by the Adaptive Immune Response
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18. Cancer, Immunity, and Immunotherapy
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THE IMMUNE SYSTEM, FOURTH EDITION
CHAPTER 1: ELEMENTS OF THE IMMUNE SYSTEM
AND THEIR ROLES IN DEFENSE
© 2015 GARLAND SCIENCE
1–1 The last cases of smallpox were reported in the .
a. 1950s
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b. 1960s
c. 1970s
d. 1980s
e. 1990s.
1–2 The first line of defense against microorganisms that infect the body is referred to as
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.
a. opportunistic immunity
b. innate immunity
c. adaptive immunity
d. primary immunity
e. central immunity.
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1–3 Which of the following pairs is mismatched?
a. innate immunity: highly specialized defenses
b. secondary immune response: immunological memory
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c. hematopoiesis: bone marrow
d. phagocytosis: uptake and killing of microbes
e. lymphocyte recirculation: continuous transport between blood and lymph.
1–4 All of the following are examples of chemical barriers of innate immunity except .
a. lactic acid
b. normal microbiota
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c. lysozyme
d. fatty acids
e. proteases.
1–5 When effector lymphocytes secrete , an inflammatory response ensues.
a. lysozyme
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b. defensins
c. lymph
d. sebum
e. cytokines.
1–6 The thin layer of cells that makes up the interior lining of the blood vessels is called the
.
a. mucosa
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b. epithelium
c. endothelium
d. connective tissue
e. lymphoid tissue.
1–7 Identify the incorrect statement regarding hematopoiesis.
a. Hematopoiesis is a continuous process that occurs throughout one’s lifetime.
b. The location for hematopoiesis differs with age.
c. Self renewal is necessary to replenish the supply of hematopoietic stem cells.
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d. Most hematopoiesis occurs in the bone marrow after birth.
e. Leukocytes, but not erythrocytes, must go through hematopoiesis in order to develop.
1–8 The progenitors of macrophages are .
a. megakaryocytes
b. dendritic cells
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c. monocytes
d. neutrophils
e. erythrocytes
f. M cells.
1–9 act as cellular messengers by delivering degraded pathogens to lymphoid organs.
a. Plasma cells
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b. Dendritic cells
c. Large granular lymphocytes
d. Mast cells
e. Basophils.
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1–10 Another name for a large granular lymphocyte is a .
a. plasma cell
b. helper T cell
c. monocyte
d. natural killer cell
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e. eosinophil.
1–11 Effector cells that secrete antibodies are known as .
a. natural killer cells
b. cytotoxic T cells
c. helper T cells
d. M cells
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e. plasma cells
f. regulatory T cells.
1–12 Spherical regions in lymph nodes containing areas that are packed densely with
proliferating B cells are called .
a. efferent vessels
b. germinal centers
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