TEST BANK for Introduction to Clinical
Pharmacology updated Edition
Trade - answer-The _______ name is the proprietary name (trademark) for a drug used
exclusively by one company (ex. Motrin, Advil)
Generic - answer-The ________ name is the public, non proprietary name for a chemical
substance approved by the FDA (ex. ibuprofen)
NSAID (non-steroidal anti-inflammatory drugs) - answer-Ibuprofen pharmacotherapeutic
classification?
Anti-inflammatory drug, analgesic, antipyretic - answer-Ibuprofen indication?
Pharmacology - answer-The study of reaction of drugs in the body, including interactions
between drugs
- Includes pharmacodynamics and pharmacokinetics
Pharmacodynamics - answer-The study of the mechanism of action (MOA) of drugs in the body
- Relationship between drug concentration and effect on the body
- Effects can be therapeutic or toxic
- How the drugs affect the body
Analgesic - answer-Drug that relieves pain
1
,Antipyretic - answer-Medication used to reduce a fever
Pharmacokinetics - answer-Study of drug actions as it moves through the body
- Relationship between concentration and time
- The way the body absorbs, distributes, metabolizes, and excretes drugs
- How the body affects the drug
Pharmacodynamics - answer-Ethanol causing slurred speech/ decreased motor skills at
moderate doses is an example of the ________ of the drug
Pharmacokinetics - answer-Ethanol metabolization in the volume of 20 mg/dL/hr in alcohol
naive patients is an example of the ________ of the drug
Pharmacogenomics - answer-The study of genetic variations that cause difference in response
among individuals or populations
- Becomes more relevant as testing becomes cheaper/ easier
Drug - answer-Any substance that brings about a change in biologic function through its
chemical action
- "key"
Receptor - answer-The component of a cell or organism that interacts with the drug
- "lock"
- Initiates the change of biochemical events leading to the drug's observed effect
- Plays a regulatory role in the drug molecule interaction with specific molecules in the
biological system
2
, Proteins - answer-Most receptors are ________
Ligand - answer-Molecule that binds to a receptor
- Ex.) Drug, neurotransmitter, hormone, messenger molecule
Endogenous Ligand - answer-Any substance that is produced within the body and selectively
binds to the type of receptor that is under study
Exogenous Ligand - answer-Any substance, originating from outside the body, that selectively
binds to the type of receptor that is under study
Hormone - answer-A natural substance that is produced in the body that influences the way the
body grows or develops
- Or a drug that is synthesized within the body
- Ex.) Cortisol, testosterone ect
Xenobiotic - answer-A chemical compound that is foreign to a living organism
Toxin - answer-Poisons of biologic origin (ex. snake/ spider venom, botulinum toxin)
- Produce harmful effects
Toxicant - answer-Poisons from non-biological origin
- Ex.) Lead, pharmaceuticals ect
3
Pharmacology updated Edition
Trade - answer-The _______ name is the proprietary name (trademark) for a drug used
exclusively by one company (ex. Motrin, Advil)
Generic - answer-The ________ name is the public, non proprietary name for a chemical
substance approved by the FDA (ex. ibuprofen)
NSAID (non-steroidal anti-inflammatory drugs) - answer-Ibuprofen pharmacotherapeutic
classification?
Anti-inflammatory drug, analgesic, antipyretic - answer-Ibuprofen indication?
Pharmacology - answer-The study of reaction of drugs in the body, including interactions
between drugs
- Includes pharmacodynamics and pharmacokinetics
Pharmacodynamics - answer-The study of the mechanism of action (MOA) of drugs in the body
- Relationship between drug concentration and effect on the body
- Effects can be therapeutic or toxic
- How the drugs affect the body
Analgesic - answer-Drug that relieves pain
1
,Antipyretic - answer-Medication used to reduce a fever
Pharmacokinetics - answer-Study of drug actions as it moves through the body
- Relationship between concentration and time
- The way the body absorbs, distributes, metabolizes, and excretes drugs
- How the body affects the drug
Pharmacodynamics - answer-Ethanol causing slurred speech/ decreased motor skills at
moderate doses is an example of the ________ of the drug
Pharmacokinetics - answer-Ethanol metabolization in the volume of 20 mg/dL/hr in alcohol
naive patients is an example of the ________ of the drug
Pharmacogenomics - answer-The study of genetic variations that cause difference in response
among individuals or populations
- Becomes more relevant as testing becomes cheaper/ easier
Drug - answer-Any substance that brings about a change in biologic function through its
chemical action
- "key"
Receptor - answer-The component of a cell or organism that interacts with the drug
- "lock"
- Initiates the change of biochemical events leading to the drug's observed effect
- Plays a regulatory role in the drug molecule interaction with specific molecules in the
biological system
2
, Proteins - answer-Most receptors are ________
Ligand - answer-Molecule that binds to a receptor
- Ex.) Drug, neurotransmitter, hormone, messenger molecule
Endogenous Ligand - answer-Any substance that is produced within the body and selectively
binds to the type of receptor that is under study
Exogenous Ligand - answer-Any substance, originating from outside the body, that selectively
binds to the type of receptor that is under study
Hormone - answer-A natural substance that is produced in the body that influences the way the
body grows or develops
- Or a drug that is synthesized within the body
- Ex.) Cortisol, testosterone ect
Xenobiotic - answer-A chemical compound that is foreign to a living organism
Toxin - answer-Poisons of biologic origin (ex. snake/ spider venom, botulinum toxin)
- Produce harmful effects
Toxicant - answer-Poisons from non-biological origin
- Ex.) Lead, pharmaceuticals ect
3
