SBB REVIEW SHEET 2026 FULL
QUESTIONS AND ACCURATE
ANSWERS
◉ ATP source for RBCs. Answer: 90% from Glycolysis (Embden-
Meyerhoff pathway)
10% from pentose phosphate pathway
◉ Methemoglobin Reductase Pathway. Answer: necessary to maintain
heme iron in ferrous (Fe2+) state
Deficiency causes accumulation of methemoglobin, nonfunctional from
of Hgb
◉ Leubering Rapaport Shunt. Answer: permits accumulation of 2,3-
DPG
◉ "Tense form" of Hgb. Answer: DEOXYGENATED
widening of beta-chain
lower affinity for O2
expels 2,3-DPG
◉ "Relaxed form" of Hgb. Answer: OXYGENATED
beta-chain pulled together
higher affinity for O2
,expels 2,3-DPG
◉ "Shift Right". Answer: higher P50 value
decreased pH (increased H+ ion), acidosis
increased 2,3-DPG
higher temperature
high pCO2
Seen in compensated anemia
◉ "Shift Left". Answer: lower P50 value
increased pH (decresed H+ ion), alkalosis
decreasede 2,3-DPG
lower temeratures
low pCO2
Seen in storage of RBC
◉ Type 2 precursor. Answer: Gal-GlcNAc
B1-4
◉ Type 1 precursor. Answer: Gal-GlcNAc
B1-3
,Secreted (Se, Le)
◉ Type 2 H antigen transeferase & Sugar. Answer: FUT-1
Alpha-2-L-fucosyltransferase
Fuctose alpha1-2
◉ A antigen transferase & sugar. Answer: D-galactosaminetrasferase
N-acetylgalactosamine alpha1-3
◉ B antigen transferase & sugar. Answer: D-galacotsyltransferase
galactose alpha1-3
◉ Ax subgroup. Answer: weakly positive anti-A
weakly positive anti-A,B
◉ Am subgroup. Answer: Negative anti-A
Secretes A & H
, ◉ Ael subgroup. Answer: Negative anti-A
Secretes H only
◉ Highest expression of H
Lowest expression of H. Answer: O>A2>B>A2B>A1>A1B> H
deficient
◉ Lewis transferase & Sugar. Answer: FUT-3
Fuctose alpha1-4
◉ Type 1 H antigen transferase & sugar. Answer: FUT-2
Fuctose alpha1-2
◉ anti-Le bh vs anti-Le bl. Answer: Anti-Le bh= reacts best with Leb &
H are on rbc
reacts best with group O and A2
does not react with A1 & B
Anti-Le bl= reacts independently of amount of H on rbc
best antisera to use when typing RBC
QUESTIONS AND ACCURATE
ANSWERS
◉ ATP source for RBCs. Answer: 90% from Glycolysis (Embden-
Meyerhoff pathway)
10% from pentose phosphate pathway
◉ Methemoglobin Reductase Pathway. Answer: necessary to maintain
heme iron in ferrous (Fe2+) state
Deficiency causes accumulation of methemoglobin, nonfunctional from
of Hgb
◉ Leubering Rapaport Shunt. Answer: permits accumulation of 2,3-
DPG
◉ "Tense form" of Hgb. Answer: DEOXYGENATED
widening of beta-chain
lower affinity for O2
expels 2,3-DPG
◉ "Relaxed form" of Hgb. Answer: OXYGENATED
beta-chain pulled together
higher affinity for O2
,expels 2,3-DPG
◉ "Shift Right". Answer: higher P50 value
decreased pH (increased H+ ion), acidosis
increased 2,3-DPG
higher temperature
high pCO2
Seen in compensated anemia
◉ "Shift Left". Answer: lower P50 value
increased pH (decresed H+ ion), alkalosis
decreasede 2,3-DPG
lower temeratures
low pCO2
Seen in storage of RBC
◉ Type 2 precursor. Answer: Gal-GlcNAc
B1-4
◉ Type 1 precursor. Answer: Gal-GlcNAc
B1-3
,Secreted (Se, Le)
◉ Type 2 H antigen transeferase & Sugar. Answer: FUT-1
Alpha-2-L-fucosyltransferase
Fuctose alpha1-2
◉ A antigen transferase & sugar. Answer: D-galactosaminetrasferase
N-acetylgalactosamine alpha1-3
◉ B antigen transferase & sugar. Answer: D-galacotsyltransferase
galactose alpha1-3
◉ Ax subgroup. Answer: weakly positive anti-A
weakly positive anti-A,B
◉ Am subgroup. Answer: Negative anti-A
Secretes A & H
, ◉ Ael subgroup. Answer: Negative anti-A
Secretes H only
◉ Highest expression of H
Lowest expression of H. Answer: O>A2>B>A2B>A1>A1B> H
deficient
◉ Lewis transferase & Sugar. Answer: FUT-3
Fuctose alpha1-4
◉ Type 1 H antigen transferase & sugar. Answer: FUT-2
Fuctose alpha1-2
◉ anti-Le bh vs anti-Le bl. Answer: Anti-Le bh= reacts best with Leb &
H are on rbc
reacts best with group O and A2
does not react with A1 & B
Anti-Le bl= reacts independently of amount of H on rbc
best antisera to use when typing RBC
