NPLEX 2 STUDY EXAM QUESTIONS AND
ANSWERS 2026 VERIFIED.
How does Zn affect methylphenidate HCl? - ANS Taking both results in better sx control
than Ritalin alone. They are both proglutamate receptors and "swim in the same direction".
What do you do if you suspect meningitis? - ANS lumbar puncture
DDX encephatitis and meningitis - ANS Encephalitis often has a focal neurological deficit
What dietary consideration is important when prescribing lithium? - ANS Do not put them
on a low-sodium diet. Monitor blood regularly. Possible to get hypothyroidism.
Bottom up paralysis - ANS Guillain-Barre Syndrome
maximum paralysis loss at 2-3 weeks.
symmetric.
increased CSF protein
often follows flu/infection
Top Down paralysis - ANS Botulism (d/t Clostridium botulinum toxin, found in home-
canned foods and honey).
1
,sensation normal.
cramps, diarrhea, dry mouth, diplopia, ptosis, loss of pupillary light reflex. afebrile.
dx by stool analysis.
Gliobastoma multiforme - ANS = Grade 4 astrocytoma.
most aggressive, highly malignant primary brain tumor in adults. Recurs almost 100% after tx.
Rehydration IV Techniques - ANS Choose largest catheter (smallest gauge).
Use isotonic solution (0.9% Normal Saline, Ringer's Lactate, D5W)
NEVER use sterile water or hypertonic solution.
Anaphylaxis IV protocol - ANS 1:1000 epinephrine for peripheral use (IM/subQ,
intratracheal)
1:10,000 epinephrine for IV.
(0.2mg max epinephrine)
50mg max IV dose for 1st Benadryl. Note: usually do epi first, then diphenhydramine.
O2 flow rate for nasal cannula - ANS 1-6 L/min
24-44% O2 concentration
for breathing victims only
O2 flow rate for resuscitation mask - ANS 6-15 L/min
35-55% O2 concentration
breath and non-breathing victims
O2 flow rate for non-rebreather mask - ANS 10-15 L/min
2
, 90+% O2 concentration
breathing victims only
O2 flow rate for Big Valve Mask - ANS 15 L/min
90+% O2 concentration
breathing and non-breathing victims
highest flow option.
2 main symptoms of shock - ANS tachycardia and hypotension
palpation of radial pulse means systolic pulse is at least? - ANS at least 80 mmHg
palpation of femoral pulse means systolic pulse is at least? - ANS at least 70 mmHg
palpation of carotid pulse means systolic pulse is at least? - ANS at least 60 mmHg
Which is worse? Closed or open globe trauma for the eye? - ANS Closed globe is worse, as
it may lead to optic nerve damage which may lead to blindness.
When to use caution with Tramadol HCl? - ANS elevated seizure risk in pts taking SSRIs,
TCAs and other opioids.
Centrally acting synthetic opioid.
THIS RX NOT ON BOARDS!
Adult dose threshold for acetaminophen - ANS 4g qd.
This is the #1 drug toxicity in the world!
3
ANSWERS 2026 VERIFIED.
How does Zn affect methylphenidate HCl? - ANS Taking both results in better sx control
than Ritalin alone. They are both proglutamate receptors and "swim in the same direction".
What do you do if you suspect meningitis? - ANS lumbar puncture
DDX encephatitis and meningitis - ANS Encephalitis often has a focal neurological deficit
What dietary consideration is important when prescribing lithium? - ANS Do not put them
on a low-sodium diet. Monitor blood regularly. Possible to get hypothyroidism.
Bottom up paralysis - ANS Guillain-Barre Syndrome
maximum paralysis loss at 2-3 weeks.
symmetric.
increased CSF protein
often follows flu/infection
Top Down paralysis - ANS Botulism (d/t Clostridium botulinum toxin, found in home-
canned foods and honey).
1
,sensation normal.
cramps, diarrhea, dry mouth, diplopia, ptosis, loss of pupillary light reflex. afebrile.
dx by stool analysis.
Gliobastoma multiforme - ANS = Grade 4 astrocytoma.
most aggressive, highly malignant primary brain tumor in adults. Recurs almost 100% after tx.
Rehydration IV Techniques - ANS Choose largest catheter (smallest gauge).
Use isotonic solution (0.9% Normal Saline, Ringer's Lactate, D5W)
NEVER use sterile water or hypertonic solution.
Anaphylaxis IV protocol - ANS 1:1000 epinephrine for peripheral use (IM/subQ,
intratracheal)
1:10,000 epinephrine for IV.
(0.2mg max epinephrine)
50mg max IV dose for 1st Benadryl. Note: usually do epi first, then diphenhydramine.
O2 flow rate for nasal cannula - ANS 1-6 L/min
24-44% O2 concentration
for breathing victims only
O2 flow rate for resuscitation mask - ANS 6-15 L/min
35-55% O2 concentration
breath and non-breathing victims
O2 flow rate for non-rebreather mask - ANS 10-15 L/min
2
, 90+% O2 concentration
breathing victims only
O2 flow rate for Big Valve Mask - ANS 15 L/min
90+% O2 concentration
breathing and non-breathing victims
highest flow option.
2 main symptoms of shock - ANS tachycardia and hypotension
palpation of radial pulse means systolic pulse is at least? - ANS at least 80 mmHg
palpation of femoral pulse means systolic pulse is at least? - ANS at least 70 mmHg
palpation of carotid pulse means systolic pulse is at least? - ANS at least 60 mmHg
Which is worse? Closed or open globe trauma for the eye? - ANS Closed globe is worse, as
it may lead to optic nerve damage which may lead to blindness.
When to use caution with Tramadol HCl? - ANS elevated seizure risk in pts taking SSRIs,
TCAs and other opioids.
Centrally acting synthetic opioid.
THIS RX NOT ON BOARDS!
Adult dose threshold for acetaminophen - ANS 4g qd.
This is the #1 drug toxicity in the world!
3
