NR 546 Final PRACTICE EXAM Psychopharmacology
Questions And Correct Answers
1. First line treatment for depression: SSRIs
2. Common side effect of SSRIs: sexual dysfunction
3. rapid cycling bipolar disorder: Minimum of 4 episodes a year
4. Goal of antidepressant therapy: complete remission of symptoms
5. Serotonin GI effects: Due to the fact that 90% of 5HT receptors are located in GI tract
6. best tolerated SSRI: Escitalopram (Lexapro) also has fewest CYP interactions
7. Lithium levels: Can be increased by NSAIDS and ACE inhibitors
Can be decreased by catteine and mania
Unattected by amiloride, furosemide, and sulindac
8. Lithium purpose: Ettective treatment for manic episodes, to prevent reoccurrence and to a lower degree is
ettective in depressive episodes
9. Lamotrigine: Well tolerated except for the propensity to cause a rash
10. Monoamines: dopamine, norepinephrine, serotonin
11. Lamotrigine: Is a mood stabilizer
12. Lithium: Well established to prevent suicide in clients with mood disorders
13. Lithium: Has a narrow therapeutic window and requires law draws
14. 1st line treatment for OCD: SSRIs are first line. Benzodiazepines are not!!!
15. Primary action of hallucinogenic drugs such as LSD,mescaline, psilocybin,
and MDMA: Agonism of 5HT2A receptors
Hallucinogens may have additional actions at other serotonin receptors (particularly 5HT1A and 5HT2C) and at other
neurotransmitter systems, and MDMA in particular also blocks the serotonin transporter (SERT)
16. Controls appetite: hypothalamus serves as the brain center that controls appetite by utilizing a complex
set of circuits and regulators. One formulation of how the hypothalamus does this is the notion that there is a major
appetite stimulating pathway whose actions are mediated by two peptides (neuropeptide Y and agouti-related protein)
17. Phentermine: Acts like amphetamine, blocking both the dopamine transporter (DAT) and the norepineph-
rine transporter (NET) and, at high doses, the vesicular monoamine transporter (VMAT)
18. Buprenorphine: Is also approved for <18 year olds
19. Disulfiram caution: Alcohol reaction may occur within two weeks of alcohol ingestion
20. Methadone: Is a full mu-receptor agonist with a long half-life, which can prevent withdrawal symptoms for
24 hours and provide steady control of cravings throughout the day. In addition to its opioid receptor activity, it is also
1/
10
, an antagonist of the N-methyl-D-aspartate (NMDA) receptor.
2/
10
Questions And Correct Answers
1. First line treatment for depression: SSRIs
2. Common side effect of SSRIs: sexual dysfunction
3. rapid cycling bipolar disorder: Minimum of 4 episodes a year
4. Goal of antidepressant therapy: complete remission of symptoms
5. Serotonin GI effects: Due to the fact that 90% of 5HT receptors are located in GI tract
6. best tolerated SSRI: Escitalopram (Lexapro) also has fewest CYP interactions
7. Lithium levels: Can be increased by NSAIDS and ACE inhibitors
Can be decreased by catteine and mania
Unattected by amiloride, furosemide, and sulindac
8. Lithium purpose: Ettective treatment for manic episodes, to prevent reoccurrence and to a lower degree is
ettective in depressive episodes
9. Lamotrigine: Well tolerated except for the propensity to cause a rash
10. Monoamines: dopamine, norepinephrine, serotonin
11. Lamotrigine: Is a mood stabilizer
12. Lithium: Well established to prevent suicide in clients with mood disorders
13. Lithium: Has a narrow therapeutic window and requires law draws
14. 1st line treatment for OCD: SSRIs are first line. Benzodiazepines are not!!!
15. Primary action of hallucinogenic drugs such as LSD,mescaline, psilocybin,
and MDMA: Agonism of 5HT2A receptors
Hallucinogens may have additional actions at other serotonin receptors (particularly 5HT1A and 5HT2C) and at other
neurotransmitter systems, and MDMA in particular also blocks the serotonin transporter (SERT)
16. Controls appetite: hypothalamus serves as the brain center that controls appetite by utilizing a complex
set of circuits and regulators. One formulation of how the hypothalamus does this is the notion that there is a major
appetite stimulating pathway whose actions are mediated by two peptides (neuropeptide Y and agouti-related protein)
17. Phentermine: Acts like amphetamine, blocking both the dopamine transporter (DAT) and the norepineph-
rine transporter (NET) and, at high doses, the vesicular monoamine transporter (VMAT)
18. Buprenorphine: Is also approved for <18 year olds
19. Disulfiram caution: Alcohol reaction may occur within two weeks of alcohol ingestion
20. Methadone: Is a full mu-receptor agonist with a long half-life, which can prevent withdrawal symptoms for
24 hours and provide steady control of cravings throughout the day. In addition to its opioid receptor activity, it is also
1/
10
, an antagonist of the N-methyl-D-aspartate (NMDA) receptor.
2/
10
