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APEA Pre-Predictor 2026/2027 (Actual Exam) – 150+ Questions with Correct Answers & Rationales | Complete NP Board Exam Study Guide ||Complete A+ Guide

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APEA Pre-Predictor 2026/2027 (Actual Exam) – 150+ Questions with Correct Answers & Rationales | Complete NP Board Exam Study Guide ||Complete A+ Guide

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APEA Pre Predictor
(Actual Exam) – 150+
Questions with Correct
Answers & Rationales |
Complete NP Board Exam
Study Guide ||Complete
A+ Guide
Question 1


A 65-year-old male presents with crushing chest pain radiating to the left arm,
diaphoresis, and nausea. What is the priority initial action?


A. Administer morphine
B. Obtain a 12-lead ECG
C. Give aspirin
D. Start IV fluids


Answer: B. Obtain a 12-lead ECG


Rationale:
A 12-lead ECG within 10 minutes is critical to diagnose STEMI vs NSTEMI. While
aspirin is important, diagnosis must be confirmed rapidly to guide reperfusion
therapy.

,Question 2


A patient presents with fatigue, pallor, and spoon-shaped nails. Lab results show
microcytic anemia. What is the most likely diagnosis?


A. Vitamin B12 deficiency
B. Iron deficiency anemia
C. Aplastic anemia
D. Hemolytic anemia


Answer: B. Iron deficiency anemia


Rationale:
Microcytic anemia + koilonychia (spoon nails) strongly indicates iron deficiency.


Question 3


A 28-year-old female presents with dysuria and frequency. Urinalysis shows positive
leukocyte esterase and nitrites. What is the first-line treatment?


A. Amoxicillin
B. Ciprofloxacin
C. Nitrofurantoin
D. Doxycycline


Answer: C. Nitrofurantoin


Rationale:
First-line for uncomplicated UTI includes nitrofurantoin or TMP-SMX.
Fluoroquinolones are avoided unless complicated.

,Question 4


A patient with hypertension and diabetes should be started on which medication for
renal protection?


A. Beta-blocker
B. Calcium channel blocker
C. ACE inhibitor
D. Thiazide diuretic


Answer: C. ACE inhibitor


Rationale:
ACE inhibitors protect against diabetic nephropathy by reducing intraglomerular
pressure.


Question 5


Which condition is associated with elevated TSH and low T4?


A. Hyperthyroidism
B. Subclinical hypothyroidism
C. Primary hypothyroidism
D. Secondary hypothyroidism


Answer: C. Primary hypothyroidism


Rationale:
High TSH + low T4 = thyroid gland failure (primary hypothyroidism).


Question 6

, A 4-year-old child presents with a barking cough and inspiratory stridor. What is the
most likely diagnosis?


A. Epiglottitis
B. Croup
C. Asthma
D. Bronchiolitis


Answer: B. Croup


Rationale:
Classic signs: barking cough + stridor, usually viral.


Question 7


A patient has a fasting glucose of 130 mg/dL on two occasions. What is the
diagnosis?


A. Prediabetes
B. Type 2 Diabetes Mellitus
C. Impaired glucose tolerance
D. Normal


Answer: B. Type 2 Diabetes Mellitus


Rationale:
Fasting glucose ≥126 mg/dL on two occasions = diabetes.


Question 8


Which medication is contraindicated in pregnancy?

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