NUR 521 EXAM 1 QUESTIONS
WITH CORRECT DETAILED
ANSWERS
What transmitter activates 4 subtypes of adrenergic receptors producing sympathetic
responses - Answer- epinepherine
beta 2 - Answer- receptor that works in the lungs and uterus
beta 1 - Answer- receptor that works in the heart and kidneys
prazosin - Answer- adrenergic antagonist
- treats HTN and BPH
- has 1st dose effect, the 1st dose can cause loss of consciousness
- perform CV exam: HR, BP, EKG before prescribing
adrenergic antagonist - Answer- class of drugs that causes direct blockage of
adrenergic receptors
clondidine - Answer- Centrally acting Alpha 2 agonist
- reduces sympathetic outflow to blood vessels and the heart causing decreased HR
and vasodilation
- educate pt to take at bedtime (sedation)
- drowsiness my lessen with time
- abruptly stoping causes rebound HTN
- high abuse potential with other drugs bc it increases euphoria
requip (ropinerole) - Answer- dopamin agonist
selective for D2 and D3 receptors
treats parkinsons and RLS
Levidopa (sinemet) - Answer- Dopaminerigc
Namenda (memantine) - Answer- NMDA receptor antagonist
- works to bind glutamate at receptor sites with allows calcium to come into the cells
- treats alzheimers
Donazepil (Aricept) - Answer- cholinesterase inhibitor
works to stop Ach form found in the brain
- treats alzheimers
, Cholinergic receptor mediate responses to: - Answer- acetylcholine
Nictotinic N (neuronal) - Answer- Promote ganglionic transmission at all ganglia of
sympathetic and parasympathetic nervous system
Promotes release of of epi from adrenal medulla
Nicotinic M (muscle) - Answer- causes contraction of skeletal muscle
Muscarinic - Answer- -located in most internal organs
-(cardiac, respiratory, GI & GU)
-Activation by Ach = excited or inhibits
- wide therapeutic response
What is the function of the Parasympathetic division of the PNS - Answer- think rest and
digest - cholinergic - muscarinic
decrease HR, increase GI movement, constrict eyes (miosis), stimulate salivation,
constrict bronchioles
What is the function of the Sympathetic division of the PNS - Answer- fight or flight
dilates pupils (mydriasis), inhibit salivation, increase HR and contractility, dilate
bronchioles, stop digestion, secrete epi and norepi
What are the functions of the autonomic nervous system - Answer- to regulate
involuntary process
What are the neurotransmitters of the nervous system? - Answer- Ach
Norepinephrine
Epinephrine
What are the receptors of the peripheral nervous system - Answer- Cholinergic
Muscarinic
What are 2 types of Cholinergic drugs? - Answer- Cholinesterase inhibitors - donepezil,
prydostigmine
Muscarinic (Cholinergic) agonist - Bethanechol
What is a contraindicated use of bethanechol? - Answer- hyperthyroidism
causes irregular cardiac rhythms
What is muscarinic (cholinergic) toxicity - Answer- too much cholinergic or
parasympathetic responses
What are s/s of muscarinic toxicity - Answer- D - diaphoresis/diarrhea
U - urination
M - myosis
B - bradycardia
WITH CORRECT DETAILED
ANSWERS
What transmitter activates 4 subtypes of adrenergic receptors producing sympathetic
responses - Answer- epinepherine
beta 2 - Answer- receptor that works in the lungs and uterus
beta 1 - Answer- receptor that works in the heart and kidneys
prazosin - Answer- adrenergic antagonist
- treats HTN and BPH
- has 1st dose effect, the 1st dose can cause loss of consciousness
- perform CV exam: HR, BP, EKG before prescribing
adrenergic antagonist - Answer- class of drugs that causes direct blockage of
adrenergic receptors
clondidine - Answer- Centrally acting Alpha 2 agonist
- reduces sympathetic outflow to blood vessels and the heart causing decreased HR
and vasodilation
- educate pt to take at bedtime (sedation)
- drowsiness my lessen with time
- abruptly stoping causes rebound HTN
- high abuse potential with other drugs bc it increases euphoria
requip (ropinerole) - Answer- dopamin agonist
selective for D2 and D3 receptors
treats parkinsons and RLS
Levidopa (sinemet) - Answer- Dopaminerigc
Namenda (memantine) - Answer- NMDA receptor antagonist
- works to bind glutamate at receptor sites with allows calcium to come into the cells
- treats alzheimers
Donazepil (Aricept) - Answer- cholinesterase inhibitor
works to stop Ach form found in the brain
- treats alzheimers
, Cholinergic receptor mediate responses to: - Answer- acetylcholine
Nictotinic N (neuronal) - Answer- Promote ganglionic transmission at all ganglia of
sympathetic and parasympathetic nervous system
Promotes release of of epi from adrenal medulla
Nicotinic M (muscle) - Answer- causes contraction of skeletal muscle
Muscarinic - Answer- -located in most internal organs
-(cardiac, respiratory, GI & GU)
-Activation by Ach = excited or inhibits
- wide therapeutic response
What is the function of the Parasympathetic division of the PNS - Answer- think rest and
digest - cholinergic - muscarinic
decrease HR, increase GI movement, constrict eyes (miosis), stimulate salivation,
constrict bronchioles
What is the function of the Sympathetic division of the PNS - Answer- fight or flight
dilates pupils (mydriasis), inhibit salivation, increase HR and contractility, dilate
bronchioles, stop digestion, secrete epi and norepi
What are the functions of the autonomic nervous system - Answer- to regulate
involuntary process
What are the neurotransmitters of the nervous system? - Answer- Ach
Norepinephrine
Epinephrine
What are the receptors of the peripheral nervous system - Answer- Cholinergic
Muscarinic
What are 2 types of Cholinergic drugs? - Answer- Cholinesterase inhibitors - donepezil,
prydostigmine
Muscarinic (Cholinergic) agonist - Bethanechol
What is a contraindicated use of bethanechol? - Answer- hyperthyroidism
causes irregular cardiac rhythms
What is muscarinic (cholinergic) toxicity - Answer- too much cholinergic or
parasympathetic responses
What are s/s of muscarinic toxicity - Answer- D - diaphoresis/diarrhea
U - urination
M - myosis
B - bradycardia
