CSO Exam - CH 18 Breast Cancer Questions
with Correct Answers 2025/2026
Breast cancer is the leading cause of cancer death - - CORRECT ANSWER ---2nd
Majority of breast cancer is from cell lining and . - - CORRECT
ANSWER---milk ducts
breast lobules
There is a lower risk of death when breast cancer pt do this. - - CORRECT ANSWER ---PA -- nurses
health study + collaborate women's longevity study
MET -- metabolic equivalent task -- 3 per week
High intake of what 2 things is beneficial? - - CORRECT ANSWER ---fruits + vegs
What percent of women will develop breast cancer if they have the BRAC1 or BRAC2 gene? - -
CORRECT ANSWER ---80%
What is the treatment if caught early stage? - - CORRECT ANSWER ---Lumpectomy --
breast conserving- -- followed by XRT
ER + disease use hormone therapy = SERMS + AI's - - CORRECT ANSWER ---SERMs
(selective estrogen receptor modulators) - tamoxifen, raloxifene, fluvestrant) -- decrease
growth of estrogen-sensitive cells by binding to the estrogen receptor
AI's (aromatase inhibitors)- anastrozole, exemestane, letrozole -- block estrogen receptors
, high-risk post-meno women had 50% reduced risk of developing cancer when using this (breast
cancer prevention trial) - - CORRECT ANSWER ---tamoxifen
NCI study of Tamoxifen vs raloxifene found what - - CORR EC T AN S W E R
-- - both effective in reducing the risk among high risk disease
what monoclonal antibody is used for breast cancers that overproduce HER2 - -
C O R R E C T A N S W E R - - -trastuzumab
AI's but not SERMS are associated with what SE? - - C O R R E C T A N S W E R - - -bone loss -
--
> Ca + Vit D
how to ERD's work? (Estrogen-receptor down-regulators) - - CO R R E C T
AN S W E R -- - block effects of estrogen In breast tissue
how to LHRHs work? (Luteinizing hormone-relasing agents) - - CO R R E C T A N S W E R - - -
Lupron, Depot, Zoladex
shut down ovaries so they do not produce estrogen
incidence of mixed ER/PR cancers - - C O R R E C T A N S W E R - - -ER - PR -
===== 20% ER + PR - ==== 10%
ER - PR + ===== 5%
HER 2 + breast cancer - - C O R R E C T A N S W E R - - -20% of
cancers fast growing + aggressive
Monoclonal antibody -- herceptin
Triple negative breast cancer - - CO R R E C T A N S W E R - - -15-20%
with Correct Answers 2025/2026
Breast cancer is the leading cause of cancer death - - CORRECT ANSWER ---2nd
Majority of breast cancer is from cell lining and . - - CORRECT
ANSWER---milk ducts
breast lobules
There is a lower risk of death when breast cancer pt do this. - - CORRECT ANSWER ---PA -- nurses
health study + collaborate women's longevity study
MET -- metabolic equivalent task -- 3 per week
High intake of what 2 things is beneficial? - - CORRECT ANSWER ---fruits + vegs
What percent of women will develop breast cancer if they have the BRAC1 or BRAC2 gene? - -
CORRECT ANSWER ---80%
What is the treatment if caught early stage? - - CORRECT ANSWER ---Lumpectomy --
breast conserving- -- followed by XRT
ER + disease use hormone therapy = SERMS + AI's - - CORRECT ANSWER ---SERMs
(selective estrogen receptor modulators) - tamoxifen, raloxifene, fluvestrant) -- decrease
growth of estrogen-sensitive cells by binding to the estrogen receptor
AI's (aromatase inhibitors)- anastrozole, exemestane, letrozole -- block estrogen receptors
, high-risk post-meno women had 50% reduced risk of developing cancer when using this (breast
cancer prevention trial) - - CORRECT ANSWER ---tamoxifen
NCI study of Tamoxifen vs raloxifene found what - - CORR EC T AN S W E R
-- - both effective in reducing the risk among high risk disease
what monoclonal antibody is used for breast cancers that overproduce HER2 - -
C O R R E C T A N S W E R - - -trastuzumab
AI's but not SERMS are associated with what SE? - - C O R R E C T A N S W E R - - -bone loss -
--
> Ca + Vit D
how to ERD's work? (Estrogen-receptor down-regulators) - - CO R R E C T
AN S W E R -- - block effects of estrogen In breast tissue
how to LHRHs work? (Luteinizing hormone-relasing agents) - - CO R R E C T A N S W E R - - -
Lupron, Depot, Zoladex
shut down ovaries so they do not produce estrogen
incidence of mixed ER/PR cancers - - C O R R E C T A N S W E R - - -ER - PR -
===== 20% ER + PR - ==== 10%
ER - PR + ===== 5%
HER 2 + breast cancer - - C O R R E C T A N S W E R - - -20% of
cancers fast growing + aggressive
Monoclonal antibody -- herceptin
Triple negative breast cancer - - CO R R E C T A N S W E R - - -15-20%
