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Introduction to Genetic Analysis
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Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A.
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Wassarman
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12th Edition
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,Table of Contents
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Chapter ss 01 ss The Genetics Revolution
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Chapter ss 02 ss Single Gene Inheritance
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Chapter ss 03 ss Independent Assortment of Genes ss ss ss 26
Chapter ss 04 ss Mapping Eukaryote Chromosomes by Recombination
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Chapter ss 05 ss Gene Interaction
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Chapter ss 06 ss The Genetics of Bacteria and Their Viruses
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Chapter ss 07 ss DNA Structure and Replication
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Chapter ss 08 ss RNA Transcription Processing and Decay
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Chapter ss 09 ss Proteins and Their Synthesis
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Chapter 10 Gene Isolation and Manipulation
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Chapter ss 11 ss Regulation of Gene Expression in Bacteria and Their Viruses
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Chapter ss 12 ss Regulation of Gene Expression in Eukaryotes
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Chapter ss 13 ss The Genetic Control of Development
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Chapter ss 14 ss Genomes and Genomics ss ss 192
Chapter ss 15 ss DNA Damage Repair and Recombination
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Chapter ss 16 ss The Dynamic Genome Transposable Elements
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Chapter ss 17 ss Large Scale Chromosomal Changes
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Chapter 18 Population Genetics
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Chapter 19 The Inheritance of Complex Traits
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Chapter 20 Evolution of Genes and Traits
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, Test s s Bank s s - s s Introduction s s to s s Genetic s s Analysis, s s 12th s s Edition s s (Griffiths, s s 2021)
Chapter 01: The Genetics Revolution
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1. The early 1900s was an important period for genetics due to which of the following major events?
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a. the rediscovery of Gregor Mendel's scientific findings
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b. Watson and Crick solving the structure of DNA
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c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
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d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore
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Boveri hypothesizing that chromosomes are the hereditary elements
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e. All of the answer options are correct.
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ANSWER: e s s s s
2. A sample of normal double-stranded DNA was found to have a guanine content of 18%.
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ssWhat is the expected proportion of adenine?
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a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b s s s s
3. In one strand of DNA, the nucleotide sequence is 5'-ATGC-3'. The complementary
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sssequence in the other strand must be
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a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b s s s s
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
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a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e s s s s
5. Which of the following is/are TRUE about genes?
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a. Genes are located on chromosomes.ss ss ss ss
b. Genes come in variants known as alleles.
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c. Genes usually encode protein products.
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d. All of the answer options are correct.
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e. None of the answer options is correct.
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ANSWER: d s s s s
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, Test s s Bank s s - s s Introduction s s to s s Genetic s s Analysis, s s 12th s s Edition s s (Griffiths, s s 2021)
6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats,
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2n = 38, while in common mice, 2n = 40. Based on this information, we can conclude
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ssthat wild-cat cells have
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a. less DNA than common-mouse cells.
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b. smaller genomes than common-mouse cells. ss ss ss ss
c. fewer DNA molecules than common-mouse cells.
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d. fewer genes than common-mouse cells.
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e. fewer sets of chromosomes than common-mouse cells.
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ANSWER: c s s s s
7. Which of the following is a component of DNA?
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a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d s s s s
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
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a. It is a double-helical structure.
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b. Sugar–phosphate backbone is always toward the outside of the DNA. ss ss ss ss ss ss ss ss ss
c. There are two hydrogen bonds between A and T and three hydrogen bonds between C and G.
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d. There are four types of nitrogenous bases.
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e. All of the answer options are correct.
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ANSWER: e s s s s
9. Which of the following is a CORRECT representation of the central dogma?
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a. RNA → DNA → protein ss ss ss ss
b. protein → DNA → RNA ss ss ss ss
c. DNA → RNA → protein ss ss ss ss
d. DNA → protein → DNA ss ss ss ss
e. None of the answer options is correct.
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ANSWER: c s s s s
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all
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the puppies produced by this dog don't have a tail. If the lack of tail is caused by a
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ssgenetic mutation, where has this mutation most likely taken place?
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a. in Cindy's gametes
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b. in the cells that should normally have given rise to Cindy's tail
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c. in the cells that should normally have given rise to Cindy's and her puppies' tails
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d. in all of Cindy's cells (including her gametes)
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e. in a gamete of one of Cindy's parents
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ANSWER: a s s s s
11. Which of the following features makes a species suitable as a model organism?
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