CMN 572 - UNIT 4 EXAM QUESTIONS
AND ANSWERS
Which is more potent: Creams or ointments? - Correct Answers -Ointments
McPhee p 100
Dangers of using topical corticosteroids around the eyes? - Correct Answers -Glaucoma
or cataracts!
McPhee p 100
How many grams of topical corticosteroid is needed to cover the entire body surface of
an adult? - Correct Answers -20 - 30 g
McPhee p 100
Emollients are most effective when applied to __________ - Correct Answers -Wet skin
McPhee p 100
Best drying agent for weepy dermatoses? - Correct Answers -WATER, applied as
repeated compresses for 15 - 30 minutes.
McPhee p 100
Lotion additives that work well as antipruritics? - Correct Answers -Camphor and
menthol (0.5%)
Pramoxine hydrochloride 1%
McPhee p 100
Side effect of topical doxepin? - Correct Answers -drowsiness
McPhee p 100
Agents of choice for pruritis when due to histamines (e.g. urticaria)? - Correct Answers -
Systemic H1 blockers, such as:
- Hydroxyzine
McPhee p 100
,Systemic agents OTHER than antihistamines that may treat pruritus better? - Correct
Answers -- *Antidepressants* like doxepin, mirtazapine (Remeron), and paroxetine
(Paxil)
- Agents that act either *centrally or peripherally directly on the neurons that perceive or
modulate pruritus* like gabapentin, pregabalin, and duloxetine (Cymbalta).
McPhee p 105
Minimum daily SPF for fair skinned people? - Correct Answers -30 SPF
McPhee p 106
Which topical antibiotics have the greatest potential for sensitization? - Correct Answers
-Neomycin and bacitracin
McPhee p 106
Definition of a *benign mole* (melanocytic nevi) - Correct Answers -Small (*less than 6
mm*) macule or papue with a well-defined border and homogenous beige or pink to
dark brown pigment.
McPhee p 106
Populations with an increased risk for melanoma? - Correct Answers -+ Patients with ≥
50 nevi with ≥ 1 atypical moles and one mole ≥ 8 mm in size
+ Patients with any number of atypical moles
McPhee p 107
What are blue nevi? - Correct Answers -+ Small, slightly elevated blue-black lesins that
favor the dorsal hands.
+ Common in patients of asian descent
McPhee p 107
Definition of freckles and lentignes? - Correct Answers -Flat brown macule, typically
between 3 mm and 5 mm in diameter.
Freckles -- kids
Lengtines -- adults (age spots)
McPhee p 108
What are seborrheic keratoses? - Correct Answers -+ Benign papules and plaques,
beige to brown or even black, 3 - 20 mm in iameter, with a velvety or warty surface.
+ Look "pasted on"
, McPhee p 108
Leading cause of death due to skin disease? - Correct Answers -Malignant melanoma
McPhee p 109
Most important prognostic factor with regard to melanomas? - Correct Answers -Tumor
thickness!
10 year survival rate:
+ < 1 mm = 95%
+ 1 - 2 mm = 80%
+ 2 - 4 mm = 55%
+ > 4 mm = 30%
(NOTE: If lymph nodes are involved, the 5 year survival rate is 62%. With distant
metastases, it is 16%.)
McPhee p 109
Different types of melanomas - Correct Answers -+ *Lentigo malignant melanoma* -
Chronically sun-exposed skin of older people
+ *Superficial spreadking malignant melanoma* - 2/3 of all melanomas on intermittently
sun-exposed skin.
+ *Nodular malignant melanomas
+ * Acral-lentiginous melanomas* - Arising on palms, soles and nail beds
+ *Ocular melanoma*
+ *Malignant melanomas on mucous membranes"
McPhee p 109
Clinical features of pigmented lesions suspicious for melanoma - Correct Answers -
Irregular notched border where the pigment appears to be spreading into the normal
surrounding skin
McPhee p 109
Most important reason for close evaluation and referral of a mole? - Correct Answers -
EVOLUTION
McPhee p 109
Diagnostic criteria for atopic dermatitis? - Correct Answers -+ Pruritus
+ Typical morphology and distribution (e.g. flexural lichenification, hand eczema, nipple
eczema and eyeid eczema in adults)
AND ANSWERS
Which is more potent: Creams or ointments? - Correct Answers -Ointments
McPhee p 100
Dangers of using topical corticosteroids around the eyes? - Correct Answers -Glaucoma
or cataracts!
McPhee p 100
How many grams of topical corticosteroid is needed to cover the entire body surface of
an adult? - Correct Answers -20 - 30 g
McPhee p 100
Emollients are most effective when applied to __________ - Correct Answers -Wet skin
McPhee p 100
Best drying agent for weepy dermatoses? - Correct Answers -WATER, applied as
repeated compresses for 15 - 30 minutes.
McPhee p 100
Lotion additives that work well as antipruritics? - Correct Answers -Camphor and
menthol (0.5%)
Pramoxine hydrochloride 1%
McPhee p 100
Side effect of topical doxepin? - Correct Answers -drowsiness
McPhee p 100
Agents of choice for pruritis when due to histamines (e.g. urticaria)? - Correct Answers -
Systemic H1 blockers, such as:
- Hydroxyzine
McPhee p 100
,Systemic agents OTHER than antihistamines that may treat pruritus better? - Correct
Answers -- *Antidepressants* like doxepin, mirtazapine (Remeron), and paroxetine
(Paxil)
- Agents that act either *centrally or peripherally directly on the neurons that perceive or
modulate pruritus* like gabapentin, pregabalin, and duloxetine (Cymbalta).
McPhee p 105
Minimum daily SPF for fair skinned people? - Correct Answers -30 SPF
McPhee p 106
Which topical antibiotics have the greatest potential for sensitization? - Correct Answers
-Neomycin and bacitracin
McPhee p 106
Definition of a *benign mole* (melanocytic nevi) - Correct Answers -Small (*less than 6
mm*) macule or papue with a well-defined border and homogenous beige or pink to
dark brown pigment.
McPhee p 106
Populations with an increased risk for melanoma? - Correct Answers -+ Patients with ≥
50 nevi with ≥ 1 atypical moles and one mole ≥ 8 mm in size
+ Patients with any number of atypical moles
McPhee p 107
What are blue nevi? - Correct Answers -+ Small, slightly elevated blue-black lesins that
favor the dorsal hands.
+ Common in patients of asian descent
McPhee p 107
Definition of freckles and lentignes? - Correct Answers -Flat brown macule, typically
between 3 mm and 5 mm in diameter.
Freckles -- kids
Lengtines -- adults (age spots)
McPhee p 108
What are seborrheic keratoses? - Correct Answers -+ Benign papules and plaques,
beige to brown or even black, 3 - 20 mm in iameter, with a velvety or warty surface.
+ Look "pasted on"
, McPhee p 108
Leading cause of death due to skin disease? - Correct Answers -Malignant melanoma
McPhee p 109
Most important prognostic factor with regard to melanomas? - Correct Answers -Tumor
thickness!
10 year survival rate:
+ < 1 mm = 95%
+ 1 - 2 mm = 80%
+ 2 - 4 mm = 55%
+ > 4 mm = 30%
(NOTE: If lymph nodes are involved, the 5 year survival rate is 62%. With distant
metastases, it is 16%.)
McPhee p 109
Different types of melanomas - Correct Answers -+ *Lentigo malignant melanoma* -
Chronically sun-exposed skin of older people
+ *Superficial spreadking malignant melanoma* - 2/3 of all melanomas on intermittently
sun-exposed skin.
+ *Nodular malignant melanomas
+ * Acral-lentiginous melanomas* - Arising on palms, soles and nail beds
+ *Ocular melanoma*
+ *Malignant melanomas on mucous membranes"
McPhee p 109
Clinical features of pigmented lesions suspicious for melanoma - Correct Answers -
Irregular notched border where the pigment appears to be spreading into the normal
surrounding skin
McPhee p 109
Most important reason for close evaluation and referral of a mole? - Correct Answers -
EVOLUTION
McPhee p 109
Diagnostic criteria for atopic dermatitis? - Correct Answers -+ Pruritus
+ Typical morphology and distribution (e.g. flexural lichenification, hand eczema, nipple
eczema and eyeid eczema in adults)
