CARN LATEST 2026 EXAM QUESTIONS AND SOLUTIONS
GRADED A+
✔✔A 22-year-old woman is brought into the emergency department by EMS with a
blood pressure of 180/102 mmHg and heart rate of 110/min. She is agitated and
appears to have paranoid delusions of people chasing her. Her behavior is hypersexual,
and her speech is incoherent. Psychomotor agitation is present. Which of the following
substances is most likely to cause the patient's presentation? - ✔✔Methamphetamine
✔✔_________ therapy- patients with depression.
________ therapy- employed in SUD.
__________ therapy- patients with BiP and SUD
________ ________- PTSD & SUD - ✔✔Interpersonal
Supportive
Integrated
Seeking safety
✔✔Cocaine blocks the reuptake of what 3 NT? - ✔✔dopamine, NE, and serotonin at the
synapse.
✔✔The vasoconstriction experienced while on cocaine is caused by what NT? -
✔✔increase in NE
✔✔PCP
(Name 3) reuptake is blocked
What 3 receptor stimulation NTs are increased:
Out of the 3 which one leads to lethargy and coma - ✔✔Dopamine & NE, serotonin
Acetylcholine, GABA, Sigma
Sigma
✔✔The inhibitory reuptake of dopamine and NE while someone is on PCP leads to: -
✔✔HTN/tachy
agitation
bronchodilation
✔✔Relapse is most likely to occur at the _______stages of recovery. - ✔✔early
✔✔What happens when one person enables another person's addictions? - ✔✔Co-
dependency
,✔✔The comorbidity of personality disorders with panic disorder is strongly associated
with _______ attempts - ✔✔suicide
✔✔Serotonin syndrome is caused by toxic levels of serotonin. It presents with:
SHIVERS
- _________
- Hyperreflexia/clonus
- Increase temp
- Vital signs (HTN/HR)
- Encephalopathy (______)
- _________
- S___________
dilated pupils and diarrhea(DD) - ✔✔Shivers
AMS
Restlessness
sweating
✔✔Serotonergic drugs include: - ✔✔triptans
MAOIs
TCA
buspirone
amphetamines,
cocaine,
levodopa,
dextromethorphan, and
several opioids
✔✔GABA is the main ________ NT of the CNS - ✔✔inhibitory
✔✔Benzos work by potentiating the effects of GABA by _______ the frequency of the
GABA chloride channel opening - ✔✔increasing
✔✔Alcohol withdrawal is characterized by
________ glutamatergic neurotransmission &
__________GABA functioning - ✔✔excessive
decreased
✔✔Becoming withdrawn and dysphoric is the rebound effect of _______commonly
called comedown or crash. - ✔✔cocaine
✔✔The tachyphylaxis following administration of indirect-acting sympathomimetic
amines such as amphetamines results from what? - ✔✔the rapid emptying of synaptic
vesicles containing the NTs
, ✔✔Which opioids has both agonist and antagonist activity? - ✔✔Nalbuphine
✔✔Buprenorphine can displace most _____ ______ opiates from mu receptors. -
✔✔full agonist
✔✔Methylnaltrexone is the quaternary amine of naltrexone that does not cross the BBB
and is a GI-specific opioid ________ that can be prescribed to reverse refractory opioid-
induced __________ - ✔✔antagonist
constipation
✔✔What type of laxatives are contraindicated in opioid-induced constipation - ✔✔Bulk-
forming laxatives, such as psyllium
✔✔A social work client reports that he is "addicted to exercise" and can't spend a day
where he does not exercise. The production of which of the following substances leads
to an addictive cycle in this individual? - ✔✔Beta-endorphins
✔✔clinical diagnosis of alcoholic hepatitis is determined in a patient with:
- rapid development/worsening of _______ + _____-related complications
- serum total bili > ___
-____ &_____ elevated > 1.5x the upper limit of normal
but < 400 with AST/ALT > ___. - ✔✔jaundice, liver
3
ALT and AST
2
✔✔______ is more specific for liver injury - ✔✔AST
✔✔Nicotine binds_______to nicotinic-_______ receptors - ✔✔selectively; cholinergic
✔✔The mechanism of action of LSD is the activation of ________ receptors -
✔✔serotonin
✔✔Lisdexamfetamine dimesylate (Vyvanse) is the first FDA-approved medication to
treat moderate to severe what? - ✔✔binge-eating disorder.
✔✔IV Flumazenil works _________
Can provoke a________ especially in a patient with a chronic history of benzo use. -
✔✔immediately
seizure,
GRADED A+
✔✔A 22-year-old woman is brought into the emergency department by EMS with a
blood pressure of 180/102 mmHg and heart rate of 110/min. She is agitated and
appears to have paranoid delusions of people chasing her. Her behavior is hypersexual,
and her speech is incoherent. Psychomotor agitation is present. Which of the following
substances is most likely to cause the patient's presentation? - ✔✔Methamphetamine
✔✔_________ therapy- patients with depression.
________ therapy- employed in SUD.
__________ therapy- patients with BiP and SUD
________ ________- PTSD & SUD - ✔✔Interpersonal
Supportive
Integrated
Seeking safety
✔✔Cocaine blocks the reuptake of what 3 NT? - ✔✔dopamine, NE, and serotonin at the
synapse.
✔✔The vasoconstriction experienced while on cocaine is caused by what NT? -
✔✔increase in NE
✔✔PCP
(Name 3) reuptake is blocked
What 3 receptor stimulation NTs are increased:
Out of the 3 which one leads to lethargy and coma - ✔✔Dopamine & NE, serotonin
Acetylcholine, GABA, Sigma
Sigma
✔✔The inhibitory reuptake of dopamine and NE while someone is on PCP leads to: -
✔✔HTN/tachy
agitation
bronchodilation
✔✔Relapse is most likely to occur at the _______stages of recovery. - ✔✔early
✔✔What happens when one person enables another person's addictions? - ✔✔Co-
dependency
,✔✔The comorbidity of personality disorders with panic disorder is strongly associated
with _______ attempts - ✔✔suicide
✔✔Serotonin syndrome is caused by toxic levels of serotonin. It presents with:
SHIVERS
- _________
- Hyperreflexia/clonus
- Increase temp
- Vital signs (HTN/HR)
- Encephalopathy (______)
- _________
- S___________
dilated pupils and diarrhea(DD) - ✔✔Shivers
AMS
Restlessness
sweating
✔✔Serotonergic drugs include: - ✔✔triptans
MAOIs
TCA
buspirone
amphetamines,
cocaine,
levodopa,
dextromethorphan, and
several opioids
✔✔GABA is the main ________ NT of the CNS - ✔✔inhibitory
✔✔Benzos work by potentiating the effects of GABA by _______ the frequency of the
GABA chloride channel opening - ✔✔increasing
✔✔Alcohol withdrawal is characterized by
________ glutamatergic neurotransmission &
__________GABA functioning - ✔✔excessive
decreased
✔✔Becoming withdrawn and dysphoric is the rebound effect of _______commonly
called comedown or crash. - ✔✔cocaine
✔✔The tachyphylaxis following administration of indirect-acting sympathomimetic
amines such as amphetamines results from what? - ✔✔the rapid emptying of synaptic
vesicles containing the NTs
, ✔✔Which opioids has both agonist and antagonist activity? - ✔✔Nalbuphine
✔✔Buprenorphine can displace most _____ ______ opiates from mu receptors. -
✔✔full agonist
✔✔Methylnaltrexone is the quaternary amine of naltrexone that does not cross the BBB
and is a GI-specific opioid ________ that can be prescribed to reverse refractory opioid-
induced __________ - ✔✔antagonist
constipation
✔✔What type of laxatives are contraindicated in opioid-induced constipation - ✔✔Bulk-
forming laxatives, such as psyllium
✔✔A social work client reports that he is "addicted to exercise" and can't spend a day
where he does not exercise. The production of which of the following substances leads
to an addictive cycle in this individual? - ✔✔Beta-endorphins
✔✔clinical diagnosis of alcoholic hepatitis is determined in a patient with:
- rapid development/worsening of _______ + _____-related complications
- serum total bili > ___
-____ &_____ elevated > 1.5x the upper limit of normal
but < 400 with AST/ALT > ___. - ✔✔jaundice, liver
3
ALT and AST
2
✔✔______ is more specific for liver injury - ✔✔AST
✔✔Nicotine binds_______to nicotinic-_______ receptors - ✔✔selectively; cholinergic
✔✔The mechanism of action of LSD is the activation of ________ receptors -
✔✔serotonin
✔✔Lisdexamfetamine dimesylate (Vyvanse) is the first FDA-approved medication to
treat moderate to severe what? - ✔✔binge-eating disorder.
✔✔IV Flumazenil works _________
Can provoke a________ especially in a patient with a chronic history of benzo use. -
✔✔immediately
seizure,