NR 507 MIDTERM Exam 2026 NR507
Advanced Pathophysiology - cardiac,
pulmonary, hematology, renal Actual
Exam Expected Questions and Answers
() (Verified Answers)-
Chamberlain
Hematopoiesis - ANSWER-blood cell formation
Fetus- liver and spleen
Adult- bone marrow
Anemia - ANSWER-A condition in which the blood is deficient in red blood cells, in
hemoglobin, or in total volume.
Erythropoiesis - ANSWER-formation of red blood cells
In kidney in response to hypoxia
macrocytic normochromic anemia - ANSWER-Large RBC's, normal hemoglobin
Folic acid or Vitamin B12 deficiency
,microcytic hypochromic anemia - ANSWER-small, abnormally shaped erythrocytes
that are not able to carry normal hemoglobin
Thalassemia- mediterranean
normocytic normochromic anemia - ANSWER-Characterized by red cells that are
relatively normal in size and normal hemoglobin
Aplastic, hemorrhagic, hemolytic, sickle cell
iron deficiency anemia - ANSWER-anemia resulting when there is not enough iron
to build hemoglobin for red blood cells
Affects children, poverty, child bearing age
Erythrocytes - ANSWER-red blood cells
Most abundant cell in the body
Responsible for tissue oxygenation
Mitotic division- 100-120 days
sickle cell anemia - ANSWER-A genetic disorder in which erythroctyes take on an
abnormal curved or "sickle" shape (Hb-s)
Thalassemia - ANSWER-Inherited defect in the ability to produce hemoglobin,
usually seen in persons of Mediterranean background.
pernicious anemia - ANSWER-Lack of mature erythrocytes caused by inability to
absorb vitamin B12 into the bloodstream
, hemolytic anemia - ANSWER-Characterized by an inadequate number of
circulating red blood cells due to the premature destruction of red blood cells by
the spleen
Pancytopenia- reduction in all 3 types of blood cells (RBC, WBC, Plt)
Erythropoietin (EPO) - ANSWER-Hormone secreted by the kidney to stimulate the
production of red blood cells by bone marrow
In response to hypoxia
In the fetus the liver produces this
Hemoglobin - ANSWER-Iron-containing protein in red blood cells that carries
oxygen for delivery to cells
4 molecules of O2
Made of polypeptide, heme, iron
anemia due to gastrectomy - ANSWER-Iron def anemia is major cause after this
Removal of stomach often leads to marked decrease in production of gastric acid.
This acid is necessary to convert dietary iron to a form that is more readily
absorbed by the duodenum
hemolytic anemia causes - ANSWER-Sickle cell disease, ABO or Rh incompatibility,
drug induced
Role of macrophages - ANSWER-Innate:
Advanced Pathophysiology - cardiac,
pulmonary, hematology, renal Actual
Exam Expected Questions and Answers
() (Verified Answers)-
Chamberlain
Hematopoiesis - ANSWER-blood cell formation
Fetus- liver and spleen
Adult- bone marrow
Anemia - ANSWER-A condition in which the blood is deficient in red blood cells, in
hemoglobin, or in total volume.
Erythropoiesis - ANSWER-formation of red blood cells
In kidney in response to hypoxia
macrocytic normochromic anemia - ANSWER-Large RBC's, normal hemoglobin
Folic acid or Vitamin B12 deficiency
,microcytic hypochromic anemia - ANSWER-small, abnormally shaped erythrocytes
that are not able to carry normal hemoglobin
Thalassemia- mediterranean
normocytic normochromic anemia - ANSWER-Characterized by red cells that are
relatively normal in size and normal hemoglobin
Aplastic, hemorrhagic, hemolytic, sickle cell
iron deficiency anemia - ANSWER-anemia resulting when there is not enough iron
to build hemoglobin for red blood cells
Affects children, poverty, child bearing age
Erythrocytes - ANSWER-red blood cells
Most abundant cell in the body
Responsible for tissue oxygenation
Mitotic division- 100-120 days
sickle cell anemia - ANSWER-A genetic disorder in which erythroctyes take on an
abnormal curved or "sickle" shape (Hb-s)
Thalassemia - ANSWER-Inherited defect in the ability to produce hemoglobin,
usually seen in persons of Mediterranean background.
pernicious anemia - ANSWER-Lack of mature erythrocytes caused by inability to
absorb vitamin B12 into the bloodstream
, hemolytic anemia - ANSWER-Characterized by an inadequate number of
circulating red blood cells due to the premature destruction of red blood cells by
the spleen
Pancytopenia- reduction in all 3 types of blood cells (RBC, WBC, Plt)
Erythropoietin (EPO) - ANSWER-Hormone secreted by the kidney to stimulate the
production of red blood cells by bone marrow
In response to hypoxia
In the fetus the liver produces this
Hemoglobin - ANSWER-Iron-containing protein in red blood cells that carries
oxygen for delivery to cells
4 molecules of O2
Made of polypeptide, heme, iron
anemia due to gastrectomy - ANSWER-Iron def anemia is major cause after this
Removal of stomach often leads to marked decrease in production of gastric acid.
This acid is necessary to convert dietary iron to a form that is more readily
absorbed by the duodenum
hemolytic anemia causes - ANSWER-Sickle cell disease, ABO or Rh incompatibility,
drug induced
Role of macrophages - ANSWER-Innate:
