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Cardiovascular Embryology Notes – Heart Development, Fetal Circulation & Congenital Defects

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Comprehensive and well-structured embryology notes on the cardiovascular system, ideal for medical and health science students. This document covers the development of the heart and vascular system, including: Formation of the cardiogenic field and heart tube Cardiac looping and chamber development Septation of the heart (atria, ventricles, outflow tract) Development of valves and conduction system Aortic arches and vascular development Also includes: Fetal circulation and postnatal changes Molecular regulation of heart development (NKX2.5, TBX5, etc.) Clinical correlations (congenital heart defects, septal defects, Tetralogy of Fallot) Clear, organized, and ideal for exam preparation and quick revision.

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Desarrollo del Aparato Cardiovascular

, Establecimiento y Estructuración del
Campo Cardiogénico Primario
• El sistema vascular surge a mitad de la 3.ª semana, cuando el embrión ya no se nutre por
difusión.
• Las células cardiacas progenitoras migran del epiblasto al mesodermo esplácnico, formando el
campo cardiogénico primario (CCP) → origen de aurículas, ventrículo izquierdo y parte del
derecho.
• El campo cardiogénico secundario (CCS) forma el resto del ventrículo derecho y el tracto de
salida (cono y tronco arterial)
• La lateralidad (izquierda-derecha) guía la torsión del corazón y la disposición de la aorta y
arteria pulmonar.
• El endodermo faríngeo induce mioblastos cardíacos e islotes sanguíneos, que originan vasos y
hematocitos por vasculogénesis.
• Los islotes se fusionan en un tubo cardíaco en herradura, base del futuro corazón y cavidad
pericárdica.

,

Connected book
 image
Thomas W. Sadler, Jan Langman Langman\'s Medical Embryology
Publisher: 2000 ISBN: 9781118910801 Edition: Unknown

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