NURS 623 MARYVILLE EXAM 3 EXAM SCRIPT
2026 TEST PAPER QUESTIONS AND
SOLUTIONS GRADED A+
◉ MOA of corticosteroids drugs. Answer: drugs that suppress
inflammation by mimicking glucocorticoid hormones
Inhibit interleikin one, tumor necrosis factor and other cytokines,
impairs phagocytosis, impairs lymphocytes, and inhibits tissue
repair
◉ indications for cortocosteriod use. Answer: Allergy or
hypersensitivity, respiratory, shock, rheumatology, neurology,
hepatic, neoplastic... basicly every organ is covered if there is an
issue.
◉ withdrawal from corticorsteriod symptoms. Answer: malaise,
myalgia, headache, nausea, fevers, hypotension and relapse of
symptoms (pain, inflammation, ashtma)
◉ what must you do with corticosteriods to prevent withdrawal.
Answer: Must taper them down, you can have possible adrenal crisis
if you do not.
,◉ corticosteriod considerations. Answer: suppression patients
response to infections- no live viral vaccines, and have increased
susceptibility to disease.
If used over 6 months: Increase blood glucose, impair immune
function (get vaccines) , impair wound healing, GI complaints
(report black tarry stools) , osteoporosis (decreases calcium),
anxiety/insomnia, sodium & fluid retention 9monitor weight and
fluid retention)
If on 1gram or more also prescribe PPI (omeprazole) to prevent PUD
contraindicated with active infection and hypersensitivity
◉ What are the adverse effects of corticosteroids if administered for
six months or more?. Answer: The main thing you want to worry
about is osteoporosis
It can also worsen diabetic control
Patients should report any tarry black stools or abdominal pain.
◉ NSAIDS. Answer: nonsteroidal anti-inflammatory drugs
,Ibprofen, aspirin, torsdol, naproxin, Mobic
◉ Arachidonic Acid Cascade. Answer: Cell membrane ►
Arachinidonic acid ► Cycloxygenerase (COX)► prostaglandin's
Or
Cell membrane ► Arachinidonic acid ► Lipoxygenase► Leukotrines
◉ NSAID mechanism of action. Answer: • NSAIDs inhibit the
enzymes COX I and II
• Results in reduction in formation of prostaglandin precursors and
thromboxanes from arachidonic acid
COX1- ibuprofen, naproxen, aspirin, when this is inhibited you are
also inhibiting the prostaglandins that protect the stomach
COX2 - celebrex more stomach proctective
◉ Drug interactions with NSAIDS. Answer: Pretty much anything
that is highly protien bound. Do not give together with
ACE inhibitors - counteracts antihypertensive effect
, BetaBlockers - counteracts antihypertensive effect
lithium - increases lithium levels
Anticoagulants - increases bleeding
Antidiabetics- increases hypoglycemic effect
◉ Black box warning for NSAIDS. Answer: May cause an increased
risk of serious cardiovascular thrombotic events:
•Patients with cardiovascular disease or with risk factors for
cardiovascular disease may be a greater risk. **
•Myocardial-infarction
•Stroke which can be fatal.**
•This risk may increase with duration of use.
NSAIDs can also cause an increased risk of serious gastrointestinal
adverse effects including
•Bleeding**
•Ulceration
•Perforation the stomach or intestines which can be fatal.
2026 TEST PAPER QUESTIONS AND
SOLUTIONS GRADED A+
◉ MOA of corticosteroids drugs. Answer: drugs that suppress
inflammation by mimicking glucocorticoid hormones
Inhibit interleikin one, tumor necrosis factor and other cytokines,
impairs phagocytosis, impairs lymphocytes, and inhibits tissue
repair
◉ indications for cortocosteriod use. Answer: Allergy or
hypersensitivity, respiratory, shock, rheumatology, neurology,
hepatic, neoplastic... basicly every organ is covered if there is an
issue.
◉ withdrawal from corticorsteriod symptoms. Answer: malaise,
myalgia, headache, nausea, fevers, hypotension and relapse of
symptoms (pain, inflammation, ashtma)
◉ what must you do with corticosteriods to prevent withdrawal.
Answer: Must taper them down, you can have possible adrenal crisis
if you do not.
,◉ corticosteriod considerations. Answer: suppression patients
response to infections- no live viral vaccines, and have increased
susceptibility to disease.
If used over 6 months: Increase blood glucose, impair immune
function (get vaccines) , impair wound healing, GI complaints
(report black tarry stools) , osteoporosis (decreases calcium),
anxiety/insomnia, sodium & fluid retention 9monitor weight and
fluid retention)
If on 1gram or more also prescribe PPI (omeprazole) to prevent PUD
contraindicated with active infection and hypersensitivity
◉ What are the adverse effects of corticosteroids if administered for
six months or more?. Answer: The main thing you want to worry
about is osteoporosis
It can also worsen diabetic control
Patients should report any tarry black stools or abdominal pain.
◉ NSAIDS. Answer: nonsteroidal anti-inflammatory drugs
,Ibprofen, aspirin, torsdol, naproxin, Mobic
◉ Arachidonic Acid Cascade. Answer: Cell membrane ►
Arachinidonic acid ► Cycloxygenerase (COX)► prostaglandin's
Or
Cell membrane ► Arachinidonic acid ► Lipoxygenase► Leukotrines
◉ NSAID mechanism of action. Answer: • NSAIDs inhibit the
enzymes COX I and II
• Results in reduction in formation of prostaglandin precursors and
thromboxanes from arachidonic acid
COX1- ibuprofen, naproxen, aspirin, when this is inhibited you are
also inhibiting the prostaglandins that protect the stomach
COX2 - celebrex more stomach proctective
◉ Drug interactions with NSAIDS. Answer: Pretty much anything
that is highly protien bound. Do not give together with
ACE inhibitors - counteracts antihypertensive effect
, BetaBlockers - counteracts antihypertensive effect
lithium - increases lithium levels
Anticoagulants - increases bleeding
Antidiabetics- increases hypoglycemic effect
◉ Black box warning for NSAIDS. Answer: May cause an increased
risk of serious cardiovascular thrombotic events:
•Patients with cardiovascular disease or with risk factors for
cardiovascular disease may be a greater risk. **
•Myocardial-infarction
•Stroke which can be fatal.**
•This risk may increase with duration of use.
NSAIDs can also cause an increased risk of serious gastrointestinal
adverse effects including
•Bleeding**
•Ulceration
•Perforation the stomach or intestines which can be fatal.
