TEST BANK FOR BASIC AND CLINICAL PHARMACOLOG
m m m m m m
Y 16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1-
m m m m m m m
66/COMPLETE GUIDE 2024-2025
m m
,CHm1.mIntroduction:mThemNaturemofmDrugsm&mDrugmDevelopmentm&mRegulation
1.
Amnursemworkingminmradiologymadministersmiodinemtomamhospitalmclientm
whomismhavingmamcomputedmtomographym(CT)mscan.mThemnursingmattendan
tmworkingmonmthemoncologymunitmadministersmchemotherapymtomhospitalmcli
entsmwhomhavemcancer.mAtmthemPublicmHealthmDepartment,mamnursingmatten
dantmadministersmammeasles-mumps-mrubellam(MMR)mvaccinemtomam14-
month-
oldmchildmasmamroutinemimmunization.mWhichmbranchmofmpharmacologymbe
stmdescribesmthemactionsmofmallmthree
nursingmattendants?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ACCURATEmCHOICE:- B
Reasoningm:->>>>>>
Pharmacologymismthemstudymofmthembiologicmeffectsmofmchemicals.mNursingm
attendantsmareminvolvedmwithmclinicalmpharmacologymormpharmacotherapeuti
cs,mwhichmismambranchmofmpharmacologymthatmdealsmwithmthemusesmofmdrugsm
tomtreat,mprevent,mandmdiagnosemdisease.mThemradiologymnursingmattendantmis
madministeringmamdrugmtomhelpmdiagnose mamdisease.mThemoncologymnursingm
attendantmismadministeringmamdrugmtomhelpmtreatmamdisease.mPharmacoecono
micsmincludesmanymcostsminvolvedminmdrugmtherapy.
Pharmacodynamicsminvolvesmhowmamdrugmaffectsmthembodymand
pharmacokineticsmismhowmthembodymactsmonmthembody.
2.
WhenminvolvedminmphasemIIImdrugmevaluationmstudies,m
whatmresponsibilitiesmwouldmthemnursingmattendantmhave
?
A) Workingmwithmanimalsmwhomaremgivenmexperimentalmdrugs
B) Choosingmappropriatemhospitalmclientsmtombeminvolvedminmthemdrugm study
C) Monitoringmandmobservingmhospitalmclientsmcloselymformadversem effects
D) Conductingmresearchmtomdeterminemeffectivenessmofmthem drug
,ACCURATEmCHOICE:- C
Reasoning:->>>>>>
PhasemIIImstudiesminvolvemusemofmamdrugminmamvastmclinicalmpopulationminm
whichmhospitalmclientsmaremaskedmtomrecordmanymsymptomsmtheymexperienc
emwhilemtakingmthemdrugs.mNursingmattendantsmmaymbemresponsiblemformhel
pingmcollectmandmanalyzemtheminformationmtombemsharedmwithmthemFoodmand
mDrugmAdministrationm(FDA)mbutmwouldmnotmconductmresearchmindependen
tlymbecausemnursingmattendantsmdomnotmprescribemmedications.mUsemofmani
malsminmdrugmtestingmismdoneminmthempreclinicalmtrials.mSelectmhospitalmclie
ntsmwhomareminvolvedminmphasemIImstudiesmtomparticipateminmstudiesmwherem
themparticipantsmhavemthemdiseasemthemdrugmismintendedmtomtreat.mThesemho
spitalmclientsmaremmonitoredmcloselymformdrugmactionmandmadversemeffects.m
PhasemImstudiesminvolvemhealthymhumanmvolunteersmwhomaremusuallympaidm
formtheirmparticipation.mNursingmattendantsmmaymobservemfor
adversemeffectsmandmtoxicity.
3.
Amphysicianmhasmorderedmintramuscularm(IM)minjectionsmofmmorphine,mam
narcotic,meverym4mhoursmasmneededmformpainminmammotormvehiclemaccidentmvi
ctim.mThemnursingmattendantmismawaremthismdrugmhasmamhighmabusempotential
.mUndermwhatmcategorymwouldmmorphinembemclassified?
A) SchedulemI
B) SchedulemII
C) SchedulemIII
D) SchedulemIV
ACCURATEmCHOICE:- B
Reasoning:->>>>>>
NarcoticsmwithmamhighmabusempotentialmaremclassifiedmasmSchedulemIImdrugs
mbecausemofmsevere mdependencemliability. mSchedulemImdrugsmhavemhighmabu
sempotentialmandmnomacceptedmmedicalmuse.mSchedulemIIImdrugsmhavemamles
sermabusempotentialmthanmIImandmanmacceptedmmedicalmuse.mSchedulemIVmdru
gsmhavemlowmabusempotentialmandmlimitedmdependencemliability.
4.
Whatmconceptmismconsideredmwhenmgenericmdrugsmaremsubstitutedmform
brandmnamemdrugs?
A) Bioavailability
, Pagem5mofm822
B) Criticalmconcentration
C) Distribution
D) Half-life
ACCURATEmCHOICE:-A
Reasoning:->>>>>>
Bioavailabilitymismthemportionmofmamdosemofmamdrugmthatmreachesmthemsyste
micmcirculationmandmismavailablemtomactmonmbodymcells.mBindersmusedminma
mgeneric mdrugmmaymnotmbemthemsamemasmthose musedminmthe mbrandmname mdr
ug.mTherefore,mthemwaymthembodymbreaksmdownmandmusesmthemdrugmmaymd
iffer,mwhichmmaymeliminatemamgenericmdrugmsubstitution.mCriticalmconcentr
ationmismthemamountmofmamdrugmthatmismneededmtomcausemamtherapeuticmeffec
tmandmshouldmnotmdiffermbetweenmgenericmandmbrandmnamemmedications.mD
istributionmismthemphasemofmpharmacokinetics,mwhichminvolvesmthemmovem
entmofmamdrugmtomthembodysmtissuesmandmismthemsameminmgenericmandmbrand
mnamemdrugs.mAmdrugsmhalf-
lifemismthemtimemitmtakesmformthemamountmofmdrugmtomdecreasemtomhalfmthemp
eakmlevel,mwhichmshouldmnotmchangemwhenmsubstitutingmamgenericm medica
tion.
5.
Amnursingmattendantmismassessingmthemhospitalmclientsmhomemmedicationmuse.mAft
er
listeningmtomthemhospitalmclientmlistmcurrentmmedications,mthemnursingmatte
ndantmasksmwhatmprioritymquestion?
A) Domyoumtakemanymgenericmmedications?
B) Aremanymofmthesemmedicationsmorphanmdrugs?
C) Aremthesemmedicationsmsafemtomtakemduringm pregnancy?
D) Domyoumtakemanymover-the-countermmedications?
ACCURATEmCHOICE:- D
Reasoning:->>>>>>
Itmismimportantmformthemnursingmattendantmtomspecificallymquestionmusemofm
over-mthe-
countermmedicationsmbecausemhospitalmclientsmmaymnotmconsidermthemmimp
ortant.mThemhospitalmclientmismunlikelymtomknowmthemmeaningmofmorphanmd
rugsmunlessmtheymtoomaremprimarymhealthmcaremproviders.mSafetymduringmpr
egnancy,musemofmamgenericmmedication,mormclassificationmofmorphanmdrugsm
aremthingsmthemhospitalmclientmwouldmbemunablemtomanswermbutmcouldmbemf
oundminmreferencembooksmifmthemnursingmattendantmwishesmtomresearchmthe
m.
m m m m m m
Y 16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1-
m m m m m m m
66/COMPLETE GUIDE 2024-2025
m m
,CHm1.mIntroduction:mThemNaturemofmDrugsm&mDrugmDevelopmentm&mRegulation
1.
Amnursemworkingminmradiologymadministersmiodinemtomamhospitalmclientm
whomismhavingmamcomputedmtomographym(CT)mscan.mThemnursingmattendan
tmworkingmonmthemoncologymunitmadministersmchemotherapymtomhospitalmcli
entsmwhomhavemcancer.mAtmthemPublicmHealthmDepartment,mamnursingmatten
dantmadministersmammeasles-mumps-mrubellam(MMR)mvaccinemtomam14-
month-
oldmchildmasmamroutinemimmunization.mWhichmbranchmofmpharmacologymbe
stmdescribesmthemactionsmofmallmthree
nursingmattendants?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ACCURATEmCHOICE:- B
Reasoningm:->>>>>>
Pharmacologymismthemstudymofmthembiologicmeffectsmofmchemicals.mNursingm
attendantsmareminvolvedmwithmclinicalmpharmacologymormpharmacotherapeuti
cs,mwhichmismambranchmofmpharmacologymthatmdealsmwithmthemusesmofmdrugsm
tomtreat,mprevent,mandmdiagnosemdisease.mThemradiologymnursingmattendantmis
madministeringmamdrugmtomhelpmdiagnose mamdisease.mThemoncologymnursingm
attendantmismadministeringmamdrugmtomhelpmtreatmamdisease.mPharmacoecono
micsmincludesmanymcostsminvolvedminmdrugmtherapy.
Pharmacodynamicsminvolvesmhowmamdrugmaffectsmthembodymand
pharmacokineticsmismhowmthembodymactsmonmthembody.
2.
WhenminvolvedminmphasemIIImdrugmevaluationmstudies,m
whatmresponsibilitiesmwouldmthemnursingmattendantmhave
?
A) Workingmwithmanimalsmwhomaremgivenmexperimentalmdrugs
B) Choosingmappropriatemhospitalmclientsmtombeminvolvedminmthemdrugm study
C) Monitoringmandmobservingmhospitalmclientsmcloselymformadversem effects
D) Conductingmresearchmtomdeterminemeffectivenessmofmthem drug
,ACCURATEmCHOICE:- C
Reasoning:->>>>>>
PhasemIIImstudiesminvolvemusemofmamdrugminmamvastmclinicalmpopulationminm
whichmhospitalmclientsmaremaskedmtomrecordmanymsymptomsmtheymexperienc
emwhilemtakingmthemdrugs.mNursingmattendantsmmaymbemresponsiblemformhel
pingmcollectmandmanalyzemtheminformationmtombemsharedmwithmthemFoodmand
mDrugmAdministrationm(FDA)mbutmwouldmnotmconductmresearchmindependen
tlymbecausemnursingmattendantsmdomnotmprescribemmedications.mUsemofmani
malsminmdrugmtestingmismdoneminmthempreclinicalmtrials.mSelectmhospitalmclie
ntsmwhomareminvolvedminmphasemIImstudiesmtomparticipateminmstudiesmwherem
themparticipantsmhavemthemdiseasemthemdrugmismintendedmtomtreat.mThesemho
spitalmclientsmaremmonitoredmcloselymformdrugmactionmandmadversemeffects.m
PhasemImstudiesminvolvemhealthymhumanmvolunteersmwhomaremusuallympaidm
formtheirmparticipation.mNursingmattendantsmmaymobservemfor
adversemeffectsmandmtoxicity.
3.
Amphysicianmhasmorderedmintramuscularm(IM)minjectionsmofmmorphine,mam
narcotic,meverym4mhoursmasmneededmformpainminmammotormvehiclemaccidentmvi
ctim.mThemnursingmattendantmismawaremthismdrugmhasmamhighmabusempotential
.mUndermwhatmcategorymwouldmmorphinembemclassified?
A) SchedulemI
B) SchedulemII
C) SchedulemIII
D) SchedulemIV
ACCURATEmCHOICE:- B
Reasoning:->>>>>>
NarcoticsmwithmamhighmabusempotentialmaremclassifiedmasmSchedulemIImdrugs
mbecausemofmsevere mdependencemliability. mSchedulemImdrugsmhavemhighmabu
sempotentialmandmnomacceptedmmedicalmuse.mSchedulemIIImdrugsmhavemamles
sermabusempotentialmthanmIImandmanmacceptedmmedicalmuse.mSchedulemIVmdru
gsmhavemlowmabusempotentialmandmlimitedmdependencemliability.
4.
Whatmconceptmismconsideredmwhenmgenericmdrugsmaremsubstitutedmform
brandmnamemdrugs?
A) Bioavailability
, Pagem5mofm822
B) Criticalmconcentration
C) Distribution
D) Half-life
ACCURATEmCHOICE:-A
Reasoning:->>>>>>
Bioavailabilitymismthemportionmofmamdosemofmamdrugmthatmreachesmthemsyste
micmcirculationmandmismavailablemtomactmonmbodymcells.mBindersmusedminma
mgeneric mdrugmmaymnotmbemthemsamemasmthose musedminmthe mbrandmname mdr
ug.mTherefore,mthemwaymthembodymbreaksmdownmandmusesmthemdrugmmaymd
iffer,mwhichmmaymeliminatemamgenericmdrugmsubstitution.mCriticalmconcentr
ationmismthemamountmofmamdrugmthatmismneededmtomcausemamtherapeuticmeffec
tmandmshouldmnotmdiffermbetweenmgenericmandmbrandmnamemmedications.mD
istributionmismthemphasemofmpharmacokinetics,mwhichminvolvesmthemmovem
entmofmamdrugmtomthembodysmtissuesmandmismthemsameminmgenericmandmbrand
mnamemdrugs.mAmdrugsmhalf-
lifemismthemtimemitmtakesmformthemamountmofmdrugmtomdecreasemtomhalfmthemp
eakmlevel,mwhichmshouldmnotmchangemwhenmsubstitutingmamgenericm medica
tion.
5.
Amnursingmattendantmismassessingmthemhospitalmclientsmhomemmedicationmuse.mAft
er
listeningmtomthemhospitalmclientmlistmcurrentmmedications,mthemnursingmatte
ndantmasksmwhatmprioritymquestion?
A) Domyoumtakemanymgenericmmedications?
B) Aremanymofmthesemmedicationsmorphanmdrugs?
C) Aremthesemmedicationsmsafemtomtakemduringm pregnancy?
D) Domyoumtakemanymover-the-countermmedications?
ACCURATEmCHOICE:- D
Reasoning:->>>>>>
Itmismimportantmformthemnursingmattendantmtomspecificallymquestionmusemofm
over-mthe-
countermmedicationsmbecausemhospitalmclientsmmaymnotmconsidermthemmimp
ortant.mThemhospitalmclientmismunlikelymtomknowmthemmeaningmofmorphanmd
rugsmunlessmtheymtoomaremprimarymhealthmcaremproviders.mSafetymduringmpr
egnancy,musemofmamgenericmmedication,mormclassificationmofmorphanmdrugsm
aremthingsmthemhospitalmclientmwouldmbemunablemtomanswermbutmcouldmbemf
oundminmreferencembooksmifmthemnursingmattendantmwishesmtomresearchmthe
m.
